{"id":257475,"date":"2026-03-05T18:14:46","date_gmt":"2026-03-05T17:14:46","guid":{"rendered":"https:\/\/r3i.org\/%e3%83%9e%e3%82%af%e3%83%ad%e8%a1%80%e7%ae%a1%e3%83%aa%e3%82%b9%e3%82%af-reduce-it%e3%81%8b%e3%82%89%e3%81%ae%e6%96%b0%e7%9f%a5%e8%a6%8b%ef%bc%9a%e3%82%a4%e3%82%b3%e3%82%b5%e3%83%9a%e3%83%b3\/"},"modified":"2026-03-09T16:18:15","modified_gmt":"2026-03-09T15:18:15","slug":"%e3%83%9e%e3%82%af%e3%83%ad%e8%a1%80%e7%ae%a1%e3%83%aa%e3%82%b9%e3%82%af-reduce-it%e3%81%8b%e3%82%89%e3%81%ae%e6%96%b0%e7%9f%a5%e8%a6%8b%ef%bc%9a%e3%82%a4%e3%82%b3%e3%82%b5%e3%83%9a%e3%83%b3","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e3%83%9e%e3%82%af%e3%83%ad%e8%a1%80%e7%ae%a1%e3%83%aa%e3%82%b9%e3%82%af-reduce-it%e3%81%8b%e3%82%89%e3%81%ae%e6%96%b0%e7%9f%a5%e8%a6%8b%ef%bc%9a%e3%82%a4%e3%82%b3%e3%82%b5%e3%83%9a%e3%83%b3\/","title":{"rendered":"\u30de\u30af\u30ed\u8840\u7ba1\u30ea\u30b9\u30af \u2013 REDUCE-IT\u304b\u3089\u306e\u65b0\u77e5\u898b\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u304c\u7dcf\u75be\u75c5\u8ca0\u8377\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;1px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_2_text_color=&#8221;gcid-primary-color&#8221; header_5_text_color=&#8221;gcid-secondary-color&#8221; text_orientation=&#8221;center&#8221; width=&#8221;99%&#8221; custom_margin=&#8221;|-147px||||&#8221; custom_padding=&#8221;|0px||||&#8221; global_colors_info=&#8221;{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}&#8221;]<\/p>\n<h2>REDUCE-IT\u304b\u3089\u306e\u65b0\u77e5\u898b\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u304c\u7dcf\u75be\u75c5\u8ca0\u8377\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059<\/h2>\n<h5><span>2026\u5e742\u6708<\/span><\/h5>\n<div>\n<p><em>\u3053\u306e\u89e3\u6790\u7d50\u679c\u306f\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306b\u3088\u308b\u6cbb\u7642\u306f\u3001\u9ad8\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u6709\u3059\u308b\u500b\u4eba\u306b\u304a\u3051\u308b\u5165\u9662\u304a\u3088\u3073\u5165\u9662\u671f\u9593\u3092\u77ed\u7e2e\u3055\u305b\u3001\u81e8\u5e8a\u7684\u304a\u3088\u3073\u60a3\u8005\u4e2d\u5fc3\u7684\u5229\u76ca\u306e\u4e21\u65b9\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3002<\/em><\/p>\n<p><em>Szarek M, Bhatt DL, Miller M, et al. Effects of icosapent ethyl on risk and duration of hospitalizations and death in REDUCE-IT. Eur J Prev Cardiol 2026: doi: 10.1093\/eurjpc\/zwag040. <\/em><\/p>\n<p><em> <\/em><\/p>\n<p><strong>\u7814\u7a76\u6982\u8981<\/strong><\/p>\n<table width=\"641\">\n<tbody>\n<tr>\n<td width=\"103\">\n<p><strong>\u76ee\u7684<\/strong><\/p>\n<\/td>\n<td width=\"522\">\n<p>REDUCE-IT (Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial)\u306b\u304a\u3044\u3066\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304c\u4e0a\u6607\u3057\u305f\u9ad8\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u304c\u7dcf\u5165\u9662\u6570\u304a\u3088\u3073\u5165\u9662\u3084\u6b7b\u4ea1\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"15\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u7814\u7a76\u30c7\u30b6\u30a4\u30f3<\/strong><\/p>\n<\/td>\n<td width=\"522\">\n<p>REDUCE-IT\u306f\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304c\u4e0a\u6607\u3057\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u304c\u78ba\u7acb\u3057\u3066\u3044\u308b\u304b\u3001\u307e\u305f\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u4e2d\u306e\u60a3\u80058,179\u540d\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7121\u4f5c\u70ba\u5316\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u8a66\u9a13\u3067\u3042\u3063\u305f\u3002\u9069\u683c\u60a3\u8005\u306f\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb2g 1\u65e52\u56de\u6295\u4e0e\u7fa4\u307e\u305f\u306f\u9069\u5408\u30d7\u30e9\u30bb\u30dc\u7fa4\u306b\u7121\u4f5c\u70ba\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f(1)\u3002\u672c\u5831\u544a\u306f\u3001\u3053\u306e\u8a66\u9a13\u306e\u4e8b\u5f8c\u89e3\u6790\u306b\u3064\u3044\u3066\u8a18\u8ff0\u3057\u3066\u3044\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"15\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u7814\u7a76\u5bfe\u8c61\u8005<\/strong><\/p>\n<\/td>\n<td width=\"522\">\n<p>REDUCE-IT\u306e\u5bfe\u8c61\u96c6\u56e3\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u7642\u6cd5\u3092\u53d7\u3051\u3066\u304a\u308a\u3001\u78ba\u7acb\u3055\u308c\u305f\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u6709\u3059\u308b\u3001\u3042\u308b\u3044\u306f50\u6b73\u4ee5\u4e0a\u3067\u7cd6\u5c3f\u75c5\u304a\u3088\u30731\u3064\u4ee5\u4e0a\u306e\u8ffd\u52a0\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u6709\u3057\u3001\u7a7a\u8179\u6642\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c91.69\u20135.63 mmol\/L\u3001\u304b\u3064\u4f4e\u5bc6\u5ea6\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb1.06\u20132.59 mmol\/L\u306e\u60a3\u8005\u3067\u3042\u3063\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"15\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee<\/strong><\/p>\n<\/td>\n<td width=\"522\">\n<p>\u7dcf\u5165\u9662\u6570\u304a\u3088\u3073\u5165\u9662\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"15\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u65b9\u6cd5<\/strong><\/p>\n<\/td>\n<td colspan=\"2\" width=\"538\">\n<p>\u65b9\u6cd5 \u7121\u4f5c\u70ba\u5316\u5f8c\u306e\u75c5\u9662\u307e\u305f\u306f\u6551\u6025\u90e8\u3078\u306e\u5165\u9662\u306f\u3001\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\u307e\u305f\u306f\u6709\u5bb3\u4e8b\u8c61\u306e\u3044\u305a\u308c\u304b\u3068\u3057\u3066\u5831\u544a\u3055\u308c\u305f\u3002\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\uff08\u3059\u306a\u308f\u3061\u3001\u5fc3\u8840\u7ba1\u3001\u975e\u5fc3\u8840\u7ba1\u3001\u307e\u305f\u306f\u539f\u56e0\u4e0d\u660e\u306b\u3088\u308b\u6b7b\u4ea1\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u51a0\u52d5\u8108\u8840\u884c\u518d\u5efa\u3001\u5fc3\u4e0d\u6574\u8108\u3001\u4e0d\u5b89\u5b9a\u72ed\u5fc3\u75c7\u3001\u3046\u3063\u8840\u6027\u5fc3\u4e0d\u5168\u3001\u8133\u5352\u4e2d\u3001\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\u3001\u304a\u3088\u3073\u672b\u68a2\u8840\u7ba1\u75be\u60a3\uff09\u306f\u3001\u72ec\u7acb\u3057\u305f\u81e8\u5e8a\u8a55\u4fa1\u59d4\u54e1\u4f1a\u306b\u3088\u3063\u3066\u5224\u5b9a\u3055\u308c\u305f\u3002\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\u3067\u306f\u306a\u3044\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u5165\u9662\u306f\u3001\u5c02\u7528\u306e\u75c7\u4f8b\u5831\u544a\u66f8\u306b\u3066\u6cbb\u9a13\u8cac\u4efb\u533b\u5e2b\u306b\u3088\u308a\u5831\u544a\u3055\u308c\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3055\u3089\u306b\u3001\u5224\u5b9a\u306b\u3088\u3063\u3066\u78ba\u8a8d\u3055\u308c\u306a\u304b\u3063\u305f\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\u306e\u305f\u3081\u306e\u5165\u9662\u306f\u3001\u6709\u5bb3\u4e8b\u8c61\u3068\u3057\u3066\u5206\u985e\u3055\u308c\u305f\u3002 \u7dcf\u5165\u9662\u6570\u306f\u3001\u7dcf\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u7af6\u5408\u30ea\u30b9\u30af\u5468\u8fba\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u89e3\u6790\u3055\u308c\u305f\u3002\u5165\u9662\u304a\u3088\u3073\u6b7b\u4ea1\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u304c\u30bc\u30ed\u3067\u3042\u308b\u53ef\u80fd\u6027\u3001\u304a\u3088\u3073\u8a66\u9a13\u671f\u9593\u4e2d\u306b\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306b\u304a\u3051\u308b\u640d\u5931\u65e5\u6570\u306e\u5272\u5408\u306f\u3001\u30bc\u30ed\u904e\u5270\u30dd\u30a2\u30bd\u30f3\u56de\u5e30\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u89e3\u6790\u3055\u308c\u305f\u3002<br \/>+4<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u4e3b\u306a\u7d50\u679c<\/strong><\/p>\n<\/td>\n<td colspan=\"2\" width=\"538\">\n<p>\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u50245.0\u5e74\u306e\u9593\u306b6,919\u4ef6\u306e\u7dcf\u5165\u9662\u304c\u3042\u308a\u30013,000\u4ef6(43.4%)\u304c\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\u306b\u3088\u308b\u3082\u306e\u30013,919\u4ef6(56.6%)\u304c\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3002\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066313\u4ef6\u5c11\u306a\u3044\u5165\u9662\u3092\u3082\u305f\u3089\u3057\u3001\u3053\u308c\u306f\u5b8c\u5168\u306b\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u3063\u305f\uff08\u30d7\u30e9\u30bb\u30dc\u3088\u308a334\u4ef6\u5c11\u306a\u3044\u5165\u9662\uff09\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u5168\u8ffd\u8de1\u671f\u9593\u306b\u308f\u305f\u308a\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306f\u5165\u9662\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u305f(\u30cf\u30b6\u30fc\u30c9\u6bd40.91, 95%\u4fe1\u983c\u533a\u9593[CI]0.84-0.98, p=0.017)\uff08\u88681\uff09\u3002\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u60a3\u8005\u306f\u3001\u5165\u9662\u3059\u308b\u3053\u3068\u306a\u304f\u8a66\u9a13\u7d42\u4e86\u307e\u3067\u751f\u5b58\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304b\u3063\u305f(\u30aa\u30c3\u30ba\u6bd41.12, 95% CI 1.02-1.22, p=0.016)\u3002\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306e\u4e2d\u3067\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u7fa4\u306e\u60a3\u8005\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u306e\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u640d\u5931\u65e5\u6570\u304c\u6709\u610f\u306b\u5c11\u306a\u304b\u3063\u305f(\u76f8\u5bfe\u30ea\u30b9\u30af0.93, 95% CI 0.93-0.94, p&lt;0.001)\uff08\u88681\uff09\u3002<\/p>\n<p><strong> <\/strong><\/p>\n<p><strong>\u88681. \u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u306b\u3088\u308b\u640d\u5931\u65e5\u6570<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"149\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"106\">\n<p>\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb<\/p>\n<p>(N=4089)<\/p>\n<\/td>\n<td width=\"105\">\n<p>\u30d7\u30e9\u30bb\u30dc<sup><\/sup><\/p>\n<p>(N=4090)<\/p>\n<\/td>\n<td width=\"97\">\n<p>HR\/OR\/RR (95% CI)<sup><\/sup><\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"65\">\n<p>p\u5024<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"149\">\n<p><strong>\u7dcf\u5165\u9662\u6570\u3001<\/strong><\/p>\n<p><strong>n\uff081000\u60a3\u8005\u5e74\u5f53\u305f\u308a\u306e\u30a4\u30d9\u30f3\u30c8\uff09<\/strong><\/p>\n<\/td>\n<td width=\"106\">\n<p>3303 (184.0)<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"105\">\n<p>3616 [203.3]<\/p>\n<\/td>\n<td width=\"97\">\n<p>HR 0.91 (0.94, 0.98)<\/p>\n<\/td>\n<td width=\"65\">\n<p>0.017<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"149\">\n<p>\u5165\u9662\uff08\u6709\u52b9\u6027\u8a55\u4fa1\u9805\u76ee\uff09<\/p>\n<\/td>\n<td width=\"106\">\n<p>1333 (74.3)<\/p>\n<\/td>\n<td width=\"105\">\n<p>1667 (93.7)<\/p>\n<\/td>\n<td width=\"97\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"65\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"149\">\n<p>\u5165\u9662\uff08\u6709\u5bb3\u4e8b\u8c61\uff09<\/p>\n<\/td>\n<td width=\"106\">\n<p>1970 (109.8)<\/p>\n<\/td>\n<td width=\"105\">\n<p>1949 (109.6)<\/p>\n<\/td>\n<td width=\"97\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"65\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"149\">\n<p>\u640d\u5931\u65e5\u6570\uff08\u5165\u9662\u306a\u3057\uff09\u3001n (%)<\/p>\n<\/td>\n<td width=\"106\">\n<p>2434 (59.5)<\/p>\n<\/td>\n<td width=\"105\">\n<p>2330 (57.0)<\/p>\n<\/td>\n<td width=\"97\">\n<p>OR 1.12 (1.02, 1.22)<\/p>\n<\/td>\n<td width=\"65\">\n<p>0.016<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"149\">\n<p>\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306e\u640d\u5931\u65e5\u6570\u3001n\uff08%\uff09\u3002<\/p>\n<\/td>\n<td width=\"106\">\n<p>187 (415)<\/p>\n<\/td>\n<td width=\"105\">\n<p>201 (435)<\/p>\n<\/td>\n<td width=\"97\">\n<p>RR 0.93 (0.93, 0.94)<\/p>\n<\/td>\n<td width=\"65\">\n<p>&lt;0.001<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"103\">\n<p><strong>\u8457\u8005\u306e\u7d50\u8ad6<\/strong><\/p>\n<\/td>\n<td colspan=\"2\" width=\"538\">\n<p>\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306f\u7dcf\u5165\u9662\u6570\u306e\u6e1b\u5c11\u3001\u304a\u3088\u3073\u5165\u9662\u3068\u6b7b\u4ea1\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u306e\u6e1b\u5c11\u3068\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u7dcf\u75be\u75c5\u8ca0\u8377\u3068\u3044\u3046\u60a3\u8005\u4e2d\u5fc3\u306e\u5c3a\u5ea6\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306e\u52b9\u679c\u306b\u95a2\u3059\u308b\u3055\u3089\u306a\u308b\u6d1e\u5bdf\u3092\u63d0\u4f9b\u3057\u305f\u3002<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong> <\/strong><\/p>\n<p><strong> <\/strong><\/p>\n<p><strong>\u30b3\u30e1\u30f3\u30c8<\/strong><\/p>\n<p>REDUCE-IT\u306f\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304c\u4e0a\u6607\u3057\u3066\u3044\u308b\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u4e2d\u306e\u9ad8\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b\u81e8\u5e8a\u7684\u5229\u76ca\u3092\u6c7a\u5b9a\u7684\u306b\u8a3c\u660e\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u521d\u56de\u304a\u3088\u3073\u7dcf\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3055\u305b\u305f(1,2)\u3002REDUCE-IT\u304b\u3089\u306e\u3053\u306e\u6700\u65b0\u306e\u89e3\u6790\u306f\u3001\u3053\u308c\u3089\u306e\u81e8\u5e8a\u7684\u5229\u76ca\u304c\u7dcf\u75be\u75c5\u8ca0\u8377\u306e\u8efd\u6e1b\u3001\u7279\u306b\u5165\u9662\u304a\u3088\u3073\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u306e\u6e1b\u5c11\u306b\u63db\u7b97\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306f\u3001\u60a3\u8005\u304c\u5165\u9662\u3059\u308b\u3053\u3068\u306a\u304f\u8a66\u9a13\u7d42\u4e86\u307e\u3067\u751f\u5b58\u3059\u308b\u53ef\u80fd\u6027\u3092\u9ad8\u3081\u305f\u3002\u3055\u3089\u306b\u3001\u305d\u306e\u5f8c\u5165\u9662\u307e\u305f\u306f\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306b\u304a\u3044\u3066\u3082\u3001\u8a66\u9a13\u671f\u9593\u4e2d\u306e\u3044\u305a\u308c\u304b\u306e\u30a4\u30d9\u30f3\u30c8\u306b\u3088\u308b\u640d\u5931\u65e5\u6570\u306e\u5272\u5408\u306b\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3053\u308c\u3089\u306e\u77e5\u898b\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u7ba1\u7406\u306b\u95a2\u9023\u3059\u308b\u591a\u5927\u306a\u7d4c\u6e08\u7684\u8ca0\u62c5\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u91cd\u8981\u306a\u610f\u5473\u3092\u6301\u3064\u3002\u4f8b\u3048\u3070\u3001\u6b27\u5dde\u9023\u5408(EU)\u3067\u306f\u3001\u3053\u306e\u30b3\u30b9\u30c8\u306f2,820\u5104\u30e6\u30fc\u30ed\u4ee5\u4e0a\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u308b(3)\u3002\u4e88\u9632\u3001\u8a3a\u65ad\u3001\u304a\u3088\u3073\u6cbb\u7642\u306e\u9032\u6b69\u306b\u3088\u308a\u751f\u5b58\u671f\u9593\u304c\u5ef6\u9577\u3059\u308b\u306b\u3064\u308c\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u62b1\u3048\u3066\u751f\u304d\u308b\u4eba\u3005\u306e\u6570\u306f\u5897\u52a0\u3057\u3066\u3044\u308b\u3002\u305d\u306e\u7d50\u679c\u3001\u4e3b\u306a\u30b3\u30b9\u30c8\u8981\u56e0\u306f\u3082\u306f\u3084\u6025\u6027\u3067\u751f\u547d\u3092\u8105\u304b\u3059\u30a8\u30d4\u30bd\u30fc\u30c9\u306e\u6cbb\u7642\u3067\u306f\u306a\u304f\u3001\u6162\u6027\u75be\u60a3\u306e\u7d99\u7d9a\u7684\u306a\u7ba1\u7406\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u5b9f\u969b\u30012023\u5e74\u306b\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306fEU\u52a0\u76df\u56fd\u306e\u5927\u90e8\u5206\u3067\u5165\u9662\u306e\u4e3b\u56e0\u3067\u3042\u308a\u3001920\u4e07\u4ef6\u306e\u5165\u9662\u306e\u539f\u56e0\u3068\u306a\u3063\u3066\u304a\u308a(4)\u3001\u7dcf\u75be\u75c5\u8ca0\u8377\u306b\u5bfe\u3059\u308b\u6700\u3082\u9ad8\u3044\u76f4\u63a5\u30b3\u30b9\u30c8\u3092\u5360\u3081\u3066\u3044\u308b\u3002\u5165\u9662\u671f\u9593\u306e\u9577\u671f\u5316\u306f\u3001\u6cbb\u7642\u3068\u30b1\u30a2\u306b\u95a2\u9023\u3059\u308b\u9ad8\u3044\u76f4\u63a5\u533b\u7642\u8cbb\u3060\u3051\u3067\u306a\u304f\u3001\u751f\u7523\u6027\u306e\u640d\u5931\u3084\u4ecb\u8b77\u8005\u306e\u8ca0\u62c5\u306b\u3088\u308b\u9ad8\u3044\u9593\u63a5\u8cbb\u306b\u3088\u308a\u3001\u5927\u304d\u306a\u793e\u4f1a\u7684\u8ca0\u62c5\u3092\u3082\u305f\u3089\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u4e8b\u5f8c\u89e3\u6790\u306b\u95a2\u9023\u3059\u308b\u6ce8\u610f\u70b9\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u3053\u308c\u3089\u306e\u77e5\u898b\u306f\u91cd\u8981\u306a\u610f\u5473\u3092\u6301\u3061\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b\u6709\u76ca\u306a\u52b9\u679c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u62e1\u5f35\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u3002REDUCE-IT\u306e5\u5e74\u9593\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u306b\u30d7\u30e9\u30bb\u30dc\u7fa4\u306e\u60a3\u8005100\u4eba\u3042\u305f\u308a100\u4ef6\u8fd1\u304f\u306e\u5165\u9662\u304c\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306b\u3088\u308b\u3053\u306e\u7387\u306e\u6e1b\u5c11\u306f\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304c\u4e0a\u6607\u3057\u3066\u3044\u308b\u3053\u308c\u3089\u306e\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u7dcf\u75be\u75c5\u8ca0\u8377\u3078\u306e\u597d\u307e\u3057\u3044\u5f71\u97ff\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ol>\n<li>Bhatt DL\u3001Steg PG\u3001Miller M\u3001\u4ed6\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u3002N Engl J Med 2019;380:11-22.<\/li>\n<li>Bhatt DL, Steg PG, Miller M, et al. Effects of icosapent ethyl on total ischemic events: from REDUCE-IT. J Am Coll Cardiol 2019;73:2791-802.<\/li>\n<li>Luengo-Fernandez R, Walli-Attaei M, Gray A,et al. Economic burden of cardiovascular diseases in the European Union: a population-based cost study. Eur Heart J 2023; 44; 4752-67.<\/li>\n<li>Eurostat (2023), Hospital discharges and length of stay statistics, <a href=\"https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Hospital_discharges_and_length_of_stay_statistics\" rel=\"nofollow\">https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Hospital_discharges_and_length_of_stay_statistics<\/a>.<\/li>\n<\/ol>\n<p><em>Key words: REDUCE-IT; icosapent ethyl, hospitalizations, total disease ab<\/em><\/p>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>REDUCE-IT\u304b\u3089\u306e\u65b0\u77e5\u898b\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u304c\u7dcf\u75be\u75c5\u8ca0\u8377\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059 2026\u5e742\u6708 \u3053\u306e\u89e3\u6790 [&hellip;]<\/p>\n","protected":false},"author":258497325,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_wpcom_ai_launchpad_about_page":false,"_wpcom_ai_launchpad_gallery_page":false,"_wpcom_ai_launchpad_contact_page":false,"_wpcom_ai_launchpad_events_page":false,"_wpcom_ai_launchpad_video_page":false,"_wpcom_ai_launchpad_portfolio_piece":false,"footnotes":""},"class_list":["post-257475","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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