{"id":254589,"date":"2024-12-27T18:39:16","date_gmt":"2024-12-27T17:39:16","guid":{"rendered":"https:\/\/r3i.org\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-07-23-%e8%84%b3%e5%8d%92%e4%b8%ad%e6%ae%8b%e5%ad%98%e3%83%aa%e3%82%b9%e3%82%af%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b\/"},"modified":"2025-02-22T16:05:03","modified_gmt":"2025-02-22T15:05:03","slug":"%e7%a4%be%e8%aa%ac-07-23-%e8%84%b3%e5%8d%92%e4%b8%ad%e6%ae%8b%e5%ad%98%e3%83%aa%e3%82%b9%e3%82%af%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-07-23-%e8%84%b3%e5%8d%92%e4%b8%ad%e6%ae%8b%e5%ad%98%e3%83%aa%e3%82%b9%e3%82%af%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b\/","title":{"rendered":"\u793e\u8aac 07\/23 – \u8133\u5352\u4e2d\u6b8b\u5b58\u30ea\u30b9\u30af\u3078\u306e\u5bfe\u7b56\u3092\u6c42\u3081\u308b"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Header” _builder_version=”4.27.4″ _module_preset=”35f37621-1062-4ae6-955d-76a3167a2aa8″ background_image=”https:\/\/r3i.org\/wp-content\/uploads\/2024\/12\/pexels-pixabay-267582.jpg&#8221<\/a>; parallax=”on” min_height=”157.9px” min_height_tablet=”100px” min_height_phone=”100px” min_height_last_edited=”on|phone” height=”116px” height_tablet=”153px” height_phone=”130px” height_last_edited=”on|phone” custom_margin_tablet=”” custom_margin_phone=”-17px||||false|false” custom_margin_last_edited=”on|phone” custom_padding=”0vw||0vw||true|false” collapsed=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22background_color_gradient_stops%22%93}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” custom_padding=”1px|||||” global_colors_info=”{}”]<\/p>\n

R3i\u793e\u8aac<\/h2>\n

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2023\u5e747\u6708<\/span><\/h5>\n
\u6b8b\u5b58\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u306b\u5bfe\u3059\u308b\u884c\u52d5\u559a\u8d77<\/span><\/h5>\n
Prof. Jean Charles Fruchart, Prof. Michel Hermans, Prof. Pierre Amarenco
\u7de8\u96c6\u30c7\u30b9\u30af\u304b\u3089<\/h6>\n

\u8133\u5352\u4e2d\u306f\u969c\u5bb3\uff08disability\uff09\u306e\u539f\u56e0\u3068\u3057\u3066\u4e16\u754c\u7b2c\u4e00\u4f4d\u3067\u3042\u308a\u3001\u6b7b\u56e0\u3068\u3057\u3066\u306f\u7b2c\u4e8c\u4f4d\u3067\u3042\u308b\u3002\u4e16\u754c\u306e\u75be\u75c5\u8ca0\u62c5\u7814\u7a76\uff08Global Burden of Disease Study\uff09\u306e\u6700\u65b0\u30c7\u30fc\u30bf\u306b\u3088\u308c\u3070\u3001\u904e\u53bb30\u5e74\u9593\uff081990\uff5e2019\u5e74\uff09\u3067\u8133\u5352\u4e2d\u306e\u7d76\u5bfe\u767a\u751f\u6570\u306f70%\u5897\u52a0\u3057\u3066\u304a\u308a\u300170\u6b73\u4ee5\u4e0a\u3067\u306f\u3055\u3089\u306b\u5897\u52a0\u7387\u304c\u9ad8\u3044\uff081\uff09\u3002\u3055\u3089\u306b\u3001\u8133\u5352\u4e2d\u306e\u75ab\u5b66\u8abf\u67fb\u3067\u306f\u6027\u5dee\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u3002\u7537\u6027\u306f\u751f\u6daf\u306e\u5927\u534a\u306b\u304a\u3044\u3066\u5973\u6027\u3088\u308a\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u304c\u3001\u5973\u6027\u306f\u8133\u5352\u4e2d\u767a\u751f\u7387\u304c\u52a0\u9f62\u3068\u3068\u3082\u306b\u5897\u52a0\u3057\u3001\u7279\u306b85\u6b73\u3092\u904e\u304e\u308b\u3068\u9ad8\u304f\u306a\u308b\u3002\u5973\u6027\u306e\u307b\u3046\u304c\u5bff\u547d\u304c\u9577\u3044\u305f\u3081\u3001\u8133\u5352\u4e2d\u306e\u6cbb\u7642\u7ba1\u7406\u304c\u9032\u6b69\u3057\u305f\u3068\u306f\u3044\u3046\u3082\u306e\u306e\u3001\u8133\u5352\u4e2d\u306e\u7f79\u60a3\u304a\u3088\u3073\u8133\u5352\u4e2d\u306b\u3088\u308b\u6b7b\u4ea1\u306b\u5360\u3081\u308b\u5973\u6027\u306e\u5272\u5408\u306f\u6bd4\u8f03\u7684\u5927\u304d\u3044<\/span>2<\/sup>\u00a0\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u9ad8\u9f62\u671f\u306e\u5ef6\u9577\u306b\u4f34\u3044\u3001\u8133\u5352\u4e2d\u3068\u305d\u308c\u306b\u4f34\u3046\u969c\u5bb3\uff08disability\uff09\u306e\u4e16\u754c\u7684\u306a\u8ca0\u62c5\u304c\u5927\u304d\u304f\u306a\u308b\u3053\u3068\u304b\u3089\u3001\u6539\u3081\u3066\u4e88\u9632\u7ba1\u7406\u306b\u6ce8\u76ee\u3059\u308b\u3053\u3068\u306f\u6709\u610f\u7fa9\u3067\u3042\u308b\u3002<\/span><\/p>\n

\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\uff08TIA\uff09\u3084\u8efd\u5ea6\u306e\u8133\u5352\u4e2d\u306e\u7ba1\u7406\u3082\u3001\u3053\u306e\u884c\u52d5\u559a\u8d77\u306e\u5bfe\u8c61\u3067\u3042\u308b\u3002\u767a\u75c7\u5f8c\u9593\u3082\u306a\u3044\uff087\u65e5\u4ee5\u5185\uff09TIA\u307e\u305f\u306f\u8efd\u5ea6\u306e\u865a\u8840\u6027\u8133\u5352\u4e2d\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u56fd\u969b\u5171\u540c\u524d\u5411\u304d\u89b3\u5bdf\u30ec\u30b8\u30b9\u30c8\u30ea\u3067\u3042\u308bTIA\u30ec\u30b8\u30b9\u30c8\u30ea\u304b\u3089\u5f97\u3089\u308c\u305f\u6700\u65b0\u30c7\u30fc\u30bf\u306f\u3001\u6b8b\u5b58\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u7ba1\u7406\u306e\u8ab2\u984c\u3092\u6d6e\u304d\u5f6b\u308a\u306b\u3057\u305f\u3002TIA\u307e\u305f\u306f\u8efd\u5ea6\u306e\u8133\u5352\u4e2d\u3092\u767a\u75c7\u3057\u305f\u60a3\u8005\u306b\u306f\u3001\u305d\u306e\u5f8c5\u5e74\u9593\u306b\u304b\u306a\u308a\u5927\u304d\u306a\u969c\u5bb3\uff08disability\uff09\u306e\u8ca0\u62c5\u304c\u751f\u3058\u308b\u304c\u3001\u305d\u306e\u307b\u3068\u3093\u3069\u306f\u4fee\u6b63\u53ef\u80fd\u306a\u30ea\u30b9\u30af\u56e0\u5b50\u306b\u3088\u308a\u4e88\u6e2c\u53ef\u80fd\u3067\u3042\u3063\u305f\u3002\u7279\u306b\u3001\u7cd6\u5c3f\u75c5\u3092\u4f75\u767a\u3057\u3066\u3044\u308b\u60a3\u8005\u3067\u306f\u3001\u5f8c\u907a\u969c\u5bb3\u3092\u4f34\u3046\u8133\u5352\u4e2d\u307e\u305f\u306f\u81f4\u6b7b\u7684\u8133\u5352\u4e2d\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c2\u500d\u4ee5\u4e0a\u3067\u3042\u3063\u305f\u00a0<\/span>3<\/sup>\u00a0\u3002\u3055\u3089\u306b\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u306e\u65e2\u5f80\u3092\u6709\u3059\u308b\u60a3\u8005\u306f\u3001\u65e2\u5f80\u306e\u306a\u3044\u60a3\u8005\u3068\u6bd4\u8f03\u3057\u3066\u30015\u5e74\u4ee5\u5185\u306b\u5927\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u304c2\uff5e3\u500d\u3068\u304b\u306a\u308a\u9ad8\u304b\u3063\u305f\u00a0<\/span>4<\/sup>\u00a0\u3002<\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” text_font_size=”14px” hover_enabled=”0″ global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22text_text_color%22%93}” sticky_enabled=”0″]<\/p>\n

\u6b8b\u5b58\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u4f4e\u6e1b\u306e\u53d6\u308a\u7d44\u307f\u306b\u304a\u3044\u3066\u3001\u81e8\u5e8a\u8a66\u9a13\u304c\u5c11\u306a\u3044\u3053\u3068\u304c\u3042\u308b\u7a0b\u5ea6\u306e\u969c\u58c1\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u3053\u308c\u306b\u3064\u3044\u3066\u306f\u3001Pierre Amarenco\u6559\u6388\u304c\u4eca\u5e742\u6708\u306b\u30e2\u30ed\u30c3\u30b3\u306e\u30de\u30e9\u30b1\u30b7\u30e5\u3067\u958b\u50ac\u3055\u308c\u305fResidual Risk Reduction Initiative\uff08\u6b8b\u5b58\u30ea\u30b9\u30af\u4f4e\u6e1b\u30a4\u30cb\u30b7\u30a2\u30c1\u30d6\uff09\u306e\u56fd\u969b\u904b\u55b6\u59d4\u54e1\u4f1a\u306e\u4f1a\u5408\u3067\u53d6\u308a\u4e0a\u3052\u3066\u3044\u308b\uff3b\u52d5\u753b\u30ea\u30f3\u30af\uff3d\u3002\u3068\u306f\u3044\u3048\u3001\u3053\u308c\u307e\u3067\u306b\u5b9f\u65bd\u3055\u308c\u305f\u30e9\u30f3\u30c9\u30de\u30fc\u30af\u8a66\u9a13\u304b\u3089\u3082\u91cd\u8981\u306a\u6559\u8a13\u304c\u5f97\u3089\u308c\u3066\u3044\u308b\u3002\u305d\u306e\u3072\u3068\u3064\u3067\u3042\u308bTreat Stroke to Target\uff08TST\uff09\u8a66\u9a13\u306f\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u306e\u5b9f\u8cea\u7684\u306a\u4f4e\u4e0b\uff08\u76ee\u6a19\u5024\u304a\u3088\u3073LDL-C\u4f4e\u4e0b\u91cf\u306e\u4e21\u65b9\u306e\u4f4e\u4e0b\uff09\u306e\u91cd\u8981\u6027\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u00a0<\/span>5 -7<\/sup>\u00a0\u3002\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u591a\u304f\u307f\u3089\u308c\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u5024\u306e\u4e0a\u6607\u3068\u8840\u6f3f\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u4f4e\u4e0b\u306e2\u3064\u3092\u6a19\u7684\u3068\u3057\u305f\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u306e\u6cbb\u7642\u306b\u3088\u308a\u3001\u8ffd\u52a0\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u304c\u5f97\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001TST\u8a66\u9a13\u3067\u306f\u3001\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306b\u304a\u3044\u3066\u8133\u5352\u4e2d\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u60a3\u8005\u306e\u30ea\u30b9\u30af\u304c36%\u4f4e\u4e0b\u3057\u305f\u00a0<\/span>5<\/sup>\u00a0\u3002<\/span><\/p>\n

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\u51a0\u52d5\u8108\u75be\u60a3\u60a3\u8005\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u7ba1\u7406\u306f\u5927\u304d\u304f\u9032\u6b69\u3057\u305f\u304c\u3001\u8133\u5352\u4e2d\u518d\u767a\u30ea\u30b9\u30af\u304a\u3088\u3073\u305d\u308c\u306b\u4f34\u3046\u8a8d\u77e5\u969c\u5bb3\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u307e\u3060\u591a\u304f\u306e\u8ab2\u984c\u304c\u6b8b\u3063\u3066\u3044\u308b\u3002\u6b8b\u5b58\u708e\u75c7\u30ea\u30b9\u30af\u304a\u3088\u3073\u8840\u6813\u30ea\u30b9\u30af\u3092\u6a19\u7684\u3068\u3057\u305fRIISC-THETIS\uff08Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis\uff09\u00a0<\/span>8<\/sup>\u00a0\u306a\u3069\u306e\u65b0\u3057\u3044\u8a66\u9a13\u306e\u7d50\u679c\u304b\u3089\u3001\u6b8b\u5b58\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u3068\u8133\u306e\u5065\u5eb7\u5897\u9032\u306b\u5f79\u7acb\u3064\u65b0\u305f\u306a\u77e5\u898b\u304c\u5f97\u3089\u308c\u308b\u3053\u3068\u306b\u671f\u5f85\u3057\u305f\u3044\u3002<\/span><\/p>\n

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\u53c2\u8003\u6587\u732e<\/strong><\/p>\n

    \n
  1. GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol 2021;20:795-820.<\/span>
    2.<\/span>\u00a0Eriksson M, \u00c5sberg S, Stibrant Sunnerhagen K, von Euler M. Sex Differences in Stroke Care and Outcome 2005-2018: Observations From the Swedish Stroke Register. Stroke 2021;52:3233-3242.<\/span>
    3.<\/span>\u00a0Hobeanu C, Lavall\u00e9e PC, Charles H et al. Risk of subsequent disabling or fatal stroke in patients with transient ischaemic attack or minor ischaemic stroke: an international, prospective cohort study. Lancet Neurol 2022;21:889-898.<\/span>
    4.<\/span>\u00a0Lavall\u00e9e PC, Charles H, Albers GW et al. Effect of atherosclerosis on 5-year risk of major vascular events in patients with transient ischaemic attack or minor ischaemic stroke: an international prospective cohort study. Lancet Neurol 2023;22:320-329.<\/span>
    5.<\/span>\u00a0Amarenco P, Kim JS, Labreuche J, et al. A comparison of two LDL cholesterol targets after ischemic stroke. N Engl J Med 2020;382(1):9<\/span>
    6.<\/span>\u00a0Amarenco P, Kim JS, Labreuche J, et al. Impact of lower versus higher LDL cholesterol targets on cardiovascular events after ischemic stroke in patients with diabetes. Diabetes 2021;70:1807-1815.<\/span>
    7.<\/span>\u00a0Amarenco P, Kim JS, Labreuche J, et al. Yield of dual therapy with statin and ezetimibe in the Treat Stroke to Target Trial. Stroke 2022; 53:3260-3267.<\/span>
    8.<\/span>\u00a0Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis (RIISC-THETIS). Available at     https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05476991<\/a><\/span><\/li>\n<\/ol>\n

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