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_builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;8px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"font-weight: 400;\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ol>\n<li style=\"font-weight: 400;\"><span>Jager KJ, Fraser SDS. The ascending rank of chronic kidney disease in the global burden of disease study. Nephrol Dial Transplant 2017;32(suppl_2):ii121-ii128.<\/span><br \/><span class=\"ref ref2\">2.<\/span><span>\u00a0Hill NR, Fatoba ST, Oke JL, et al. Global prevalence of chronic kidney disease \u2013 a systematic review and meta-analysis. Plos One 2016;11<\/span><sup>7<\/sup><span>:e0158765.<\/span><br \/><span class=\"ref ref3\">3.<\/span><span>\u00a0Jha V, Garcia-Garcia G, Iseki K. et al. Chronic kidney disease: global dimension and perspectives. Lancet 2013; 382: 260\u2013272.<\/span><br \/><span class=\"ref ref4\">4.<\/span><span>\u00a0Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 2015;373:2117\u20132128.<\/span><br \/><span class=\"ref ref5\">5.<\/span><span>\u00a0Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med 2017;377: 644\u2013657.<\/span><br \/><span class=\"ref ref6\">6.<\/span><span>\u00a0Wiviott SD, Raz I, Bonaca MP, et al. Dapagliflozin and cardiovascular outcomes in type 2 diabetes. N Engl J Med 2019;380:347\u2013335.<\/span><br \/><span class=\"ref ref7\">7.<\/span><span>\u00a0Perkovic V, Jardine MJ, Neal B, et al. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. N Engl J Med 2019;380:2295-2306.<\/span><br \/><span class=\"ref ref8\">8.<\/span><span>\u00a0Heerspink HJL, Stef\u00e1nsson BV, Correa-Rotter R, et al. Dapagliflozin in patients with chronic kidney disease. N Engl J Med 2020;383:1436-1446.<\/span><br \/><span class=\"ref ref9\">9.<\/span><span>\u00a0EMPA-KIDNEY. <a href=\"https:\/\/www.empakidney.org\/news\/empa-kidney-trial-stops-early-due-to-evidence-of-efficacy\" rel=\"nofollow\">https:\/\/www.empakidney.org\/news\/empa-kidney-trial-stops-early-due-to-evidence-of-efficacy<\/a>.<\/span><br \/><span class=\"ref ref10\">10.<\/span><span>\u00a0Hager MR, Narla AD, Tannock LR. Dyslipidemia in patients with chronic kidney disease. Rev Endocr Metab Disord. 2017;18:29-40.<\/span><br \/><span class=\"ref ref11\">11.<\/span><span>\u00a0Moorhead JF, Chan MK, El-Nahas M, et al. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet 1982;2:1309\u20131311.<\/span><br \/><span class=\"ref ref12\">12.<\/span><span>\u00a0Stanifer JW, Charytan DM, White J, Lokhnygina Y, Cannon CP, Roe MT, Blazing MA. Benefit of ezetimibe added to simvastatin in reduced kidney function. J Am Soc Nephrol. 2017;28:3034-3043.<\/span><br \/><span class=\"ref ref13\">13.<\/span><span>\u00a0Yokote K, Yamashita S, Arai H, Araki E, Suganami H, Ishibashi S, Of The K-Study Group OB. Long-term efficacy and safety of pemafibrate, a novel Selective Peroxisome Proliferator-Activated Receptor-\u03b1 Modulator (SPPARM\u03b1), in dyslipidemic patients with renal impairment. Int J Mol Sci 2019;20<\/span><sup>3<\/sup><span>.<\/span><\/li>\n<\/ol>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R3i\u793e\u8aac\u6162\u6027\u814e\u81d3\u75c5\u306b\u304a\u3051\u308b\u6b8b\u5b58\u8840\u7ba1\u30ea\u30b9\u30af\uff1a\u65b0\u305f\u306a\u9078\u629e\u80a2\u306e\u767b\u5834 Prof. Jean Charles Fruc [&hellip;]<\/p>\n","protected":false},"author":258497324,"featured_media":0,"parent":254286,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_wpcom_ai_launchpad_about_page":false,"_wpcom_ai_launchpad_gallery_page":false,"_wpcom_ai_launchpad_contact_page":false,"_wpcom_ai_launchpad_events_page":false,"_wpcom_ai_launchpad_video_page":false,"_wpcom_ai_launchpad_portfolio_piece":false,"footnotes":""},"class_list":["post-254586","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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