{"id":254530,"date":"2024-12-30T18:21:54","date_gmt":"2024-12-30T17:21:54","guid":{"rendered":"https:\/\/r3i.org\/r3i%e7%a4%be%e8%aa%ac\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\/"},"modified":"2025-02-22T17:18:28","modified_gmt":"2025-02-22T16:18:28","slug":"%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\/","title":{"rendered":"\u8ad6\u8aac 05\/21 &#8211; 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box_shadow_style=&#8221;preset2&#8243; global_colors_info=&#8221;{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22border_color_all%22%93}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;14px&#8221; header_5_text_color=&#8221;gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf&#8221; header_6_text_color=&#8221;gcid-secondary-color&#8221; hover_enabled=&#8221;0&#8243; inline_fonts=&#8221;Abyssinica SIL&#8221; global_colors_info=&#8221;{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_5_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h5 style=\"text-align: center;\"><span style=\"font-family: 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OUTCOMES\u8a66\u9a13\uff09\u306a\u3069\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3059\u308b\u3053\u3068\u3067\u81e8\u5e8a\u7684\u306a\u30e1\u30ea\u30c3\u30c8\u304c\u5f97\u3089\u308c\u308b\u304c\u3001\u3044\u305a\u308c\u306e\u6226\u7565\u3082\u3053\u306e\u30ea\u30b9\u30af\u3092\u56de\u907f\u3067\u304d\u3066\u306f\u3044\u306a\u3044\u00a0<\/span><sup>1-3<\/sup><span>\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u3053\u306e\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u306f\u3001\u7121\u6570\u306e\u4ed6\u306e\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3053\u308c\u3089\u306e\u8981\u56e0\u306b\u306f\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u591a\u304f\u542b\u3080\u30ea\u30dd\u86cb\u767d\u3084\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u30ec\u30d9\u30eb\u306e\u4e0a\u6607\u306b\u3088\u3063\u3066\u3082\u305f\u3089\u3055\u308c\u308b\u30ea\u30b9\u30af\u306a\u3069\u3001\u8102\u8cea\u95a2\u9023\u306e\u56e0\u5b50\u3084<\/span><sup>4<\/sup><span>\u3001\u8840\u6813\u5f62\u6210\u4fc3\u9032\u56e0\u5b50\u3092\u542b\u3080\u975e\u8102\u8cea\u95a2\u9023\u56e0\u5b50\u306a\u3069\u304c\u3042\u308b\u3002\u76f4\u8fd1\u306e\u5831\u544a\u3067\u306f\u3001NOD-like receptor protein-3\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u3067\u6b8b\u5b58\u30ea\u30b9\u30af\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u30a4\u30f3\u30d5\u30e9\u30de\u30bd\u30fc\u30e0\u306e\u6d3b\u6027\u5316\u306b\u95a2\u3057\u3066,\u305d\u306e\u5f79\u5272\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u00a0<\/span><sup>5,6<\/sup><span>\u3002<\/span><\/p>\n<p><span>\u3057\u304b\u3057\u3001\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u6982\u5ff5\u306f\u78ba\u7acb\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u306e\u3001\u30a4\u30d9\u30f3\u30c8\u518d\u767a\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3092\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u7279\u5b9a\u3059\u3079\u304d\u304b\u306f\u307e\u3060\u660e\u3089\u304b\u3067\u306f\u306a\u3044\u3002\u5b9f\u969b\u3001LDL-C\u4f4e\u4e0b\u4f5c\u7528\u306e\u9ad8\u3044\u6cbb\u7642\u6cd5\u304c\u65e5\u5e38\u81e8\u5e8a\u3067\u5c0e\u5165\u3055\u308c\u305f\u7d50\u679c\u3001\u6b8b\u5b58\u30ea\u30b9\u30af\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u306eLDL-C\u5f79\u5272\u306f\u3069\u306e\u7a0b\u5ea6\u304b\u3001\u3042\u308b\u3044\u306f\u81e8\u5e8a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u4ed6\u306e\u8102\u8cea\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u65b9\u304c\u3088\u308a\u9069\u5207\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u306f\u4e0d\u78ba\u5b9f\u3067\u3042\u308b\u3002\u3053\u306e\u3088\u3046\u306a\u7591\u554f\u306f\u3001\u73fe\u5728\u5229\u7528\u53ef\u80fd\u306a\u6cbb\u7642\u6cd5\u306e\u52b9\u679c\u304c\u9650\u754c\u306b\u9054\u3057\u305f\u3068\u304d\u306b\u3001\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3057\u3001\u500b\u5225\u5316\u6cbb\u7642\u3092\u9032\u3081\u308b\u4e0a\u3067\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002\u4eca\u6708\u306e\u30d5\u30a9\u30fc\u30ab\u30b9\u3067\u7d39\u4ecb\u3059\u308b\u7814\u7a76\u306f\u3001\u3053\u306e\u7591\u554f\u3092\u6839\u62e0\u306b\u5b9f\u65bd\u3055\u308c\u3066\u3044\u308b\u3002<\/span><\/p>\n<p><span>\u8457\u8005\u3089\u306f\u3001\u524d\u5411\u304d\u89b3\u5bdf\u7814\u7a76\u3067\u3042\u308bCopenhagen General Practice Study\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u800513,015\u4f8b\u306e\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001LDL-C\u3001\u975e\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08non-HDL-C\uff09\u3001\u30a2\u30dd\u30ea\u30dd\u86cb\u767d\uff08apo\uff09B\u304c\u3001\u8102\u8cea\u306b\u95a2\u9023\u3057\u305f\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u3069\u306e\u3088\u3046\u306b\u6a5f\u80fd\u3059\u308b\u304b\u3092\u8a55\u4fa1\u3057\u305f<\/span><sup>7<\/sup><span>\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u4e00\u81f4\u30fb\u4e0d\u4e00\u81f4\uff08\u30b3\u30f3\u30b3\u30fc\u30c0\u30f3\u30b9\u3001\u30c7\u30a3\u30b9\u30b3\u2015\u30c0\u30f3\u30b9\uff09\u89e3\u6790\u3092\u7528\u3044\u3066\u3001\u4e2d\u592e\u5024\u304b\u3089\u306e\u5909\u5316\u306e\u65b9\u5411\u6027\uff08LDL-C\u304c\u4e2d\u592e\u5024\u3092\u4e0b\u56de\u308a\u3001non-HDL-C\u307e\u305f\u306fapoB\u304c\u4e2d\u592e\u5024\u3092\u4e0a\u56de\u308b\u5834\u5408\u3001\u307e\u305f\u306f\u305d\u306e\u9006\u306e\u5834\u5408\uff09\u306b\u5fdc\u3058\u3066\u3001\u3053\u308c\u3089\u306e\u95a2\u9023\u5909\u6570\u306e\u4fa1\u5024\u304c\u3069\u3046\u5909\u5316\u3059\u308b\u304b\u3092\u691c\u8a0e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u672c\u5831\u544a\u3067\u306fLDL-C\u3067\u306f\u306a\u304f\u3001apoB\u307e\u305f\u306fnon-HDL-C\u306e\u4e0a\u6607\u306e\u307b\u3046\u304c\u3001\u7dcf\u6b7b\u4ea1\u304a\u3088\u3073\u5fc3\u7b4b\u6897\u585e\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3002\u8457\u8005\u3089\u306f\u3001LDL-C\u5024\u304c\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u308b\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u306f\u3001non-HDL-C\u3088\u308a\u3082apoB\u306e\u65b9\u304c\u3088\u308a\u6b63\u78ba\u306a\u6b8b\u5b58\u30ea\u30b9\u30af\u306e\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b\u53ef\u80fd\u6027\u3092\u793a\u5506\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u306f\u904e\u53bb\u306e\u5831\u544a<\/span><sup>8,9<\/sup><span>\u3068\u3082\u4e00\u90e8\u3067\u4e00\u81f4\u3057\u3066\u3044\u308b\u3002<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column 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better\u300d\u306e\u30d1\u30e9\u30c0\u30a4\u30e0\u306b\u5f93\u3063\u3066\u3001\u6cbb\u7642\u4ecb\u5165\u306e\u5bfe\u8c61\u3068\u306a\u308b\u512a\u5148\u7684\u306a\u30ea\u30dd\u86cb\u767d\u3067\u3042\u308b\u3053\u3068\u306b\u5909\u308f\u308a\u306f\u306a\u3044<\/span><sup>10<\/sup><span>\u00a0\u3002\u3057\u304b\u3057\u3001\u672c\u7814\u7a76\u306e\u7d50\u679c\u306f\u3001\u30ea\u30b9\u30af\u8a55\u4fa1\u306b\u304a\u3044\u3066LDL-C\u6fc3\u5ea6\u306e\u307f\u3092\u8003\u616e\u3059\u308b\u3053\u3068\u306e\u9650\u754c\u3082\u793a\u3057\u3066\u3044\u308b\u3002LDL-C\u6fc3\u5ea6\u304c\u5341\u5206\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u308b\u9ad8\u30ea\u30b9\u30af\u306e\u60a3\u8005\u3067\u306f\u3001non-HDL-C\u307e\u305f\u306fapoB\u306e\u3044\u305a\u308c\u304b\u304c\u3001\u6b8b\u5b58\u3059\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u3088\u308a\u7684\u78ba\u306b\u53cd\u6620\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u3053\u308c\u3089\u306e\u30de\u30fc\u30ab\u30fc\u304c\u4f55\u3092\u8868\u3057\u3066\u3044\u308b\u304b\u3092\u8003\u3048\u308b\u3068\u3001\u3053\u308c\u306f\u79d1\u5b66\u7684\u306b\u3082\u7406\u306b\u304b\u306a\u3063\u3066\u3044\u308b\u3002non-HDL-C\u306f\u3001LDL-C\u3092\u542b\u3080\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u30ea\u30dd\u86cb\u767d\u8cea\u306e\u7dcf\u91cf\u3092\u793a\u3059\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308a\u3001\u4e00\u65b9\u3001apoB\u306f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u306eapoB\u542b\u6709\u30ea\u30dd\u86cb\u767d\u8cea\uff08\u3053\u308c\u3089\u306e\u30ea\u30dd\u86cb\u767d\u8cea\u306f\u3001\u305d\u308c\u305e\u308c1\u3064\u306eapoB\u5206\u5b50\u3092\u542b\u3080\uff09\u306e\u5faa\u74b0\u6570\u3092\u76f4\u63a5\u6e2c\u5b9a\u3059\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u7cd6\u5c3f\u75c5\u3001\u80a5\u6e80\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u3092\u4f34\u3046\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u3092\u6709\u3059\u308b\u9ad8\u30ea\u30b9\u30af\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u306f\u3001\u4e21\u65b9\u306e\u691c\u67fb\u3092\u884c\u3046\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308a\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u591a\u304f\u542b\u3080\u30ea\u30dd\u86cb\u767d\u306e\u4ee3\u8b1d\u7523\u7269\u3067\u3042\u308b\u30ec\u30e0\u30ca\u30f3\u30c8\u30ea\u30dd\u86cb\u767d\u306b\u542b\u307e\u308c\u308b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306b\u8d77\u56e0\u3059\u308b\u6b8b\u5b58\u30ea\u30b9\u30af\u3092\u8003\u616e\u3057\u305f\u6cbb\u7642\u6226\u7565\u304c\u53ef\u80fd\u306b\u306a\u308b\u3002<\/span><\/p>\n<p><span>\u7d50\u8ad6\u3068\u3057\u3066\u3001\u6b8b\u5b58\u3059\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u5bfe\u51e6\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u65b0\u305f\u306a\u6cbb\u7642\u6a19\u7684\u3060\u3051\u3067\u306a\u304f\u3001\u305d\u306e\u30ea\u30b9\u30af\u3092\u7279\u5b9a\u3059\u308b\u305f\u3081\u306e\u65b0\u305f\u306a\u6226\u7565\u3082\u5fc5\u8981\u3067\u3042\u308b\u3002\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u539f\u56e0\u3068\u306a\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u591a\u304f\u542b\u3080\u30ea\u30dd\u86cb\u767d\u3068\u30ea\u30dd\u86cb\u767d(a)\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u51fa\u73fe\u306b\u3088\u308a\u3001\u3053\u306e2\u3064\u306e\u8981\u7d20\u306f\u307e\u3059\u307e\u3059\u91cd\u8981\u306b\u306a\u3063\u3066\u304f\u308b\u3060\u308d\u3046\u3002<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;8px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"font-weight: 400;\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ol>\n<li style=\"font-weight: 400;\">\n<div class=\"article\">Ridker PM, Everett BM, Thuren T, et al. Antiinflammatory therapy with canakinumab for atherosclerotic disease. N Engl J Med 2017;377:1119\u201331.<br \/><span class=\"ref ref2\">2.<\/span>\u00a0Sabatine MS, Giugliano RP, Keech AC, et al. Evolocumab and clinical outcomes in patients with cardiovascular disease. N Engl J Med 2017;376:1713\u201322<br \/><span class=\"ref ref3\">3.<\/span>\u00a0Schwartz GG, Steg PG, Szarek M, et al. Alirocumab and cardiovascular outcomes after acute coronary syndrome. N Engl J Med 2018;379:2097\u2013107.<br \/><span class=\"ref ref4\">4.<\/span>\u00a0Hoogeveen RC, Ballantyne CM. Residual cardiovascular risk at low LDL: remnants, lipoprotein(a), and inflammation. Clin Chem 2021;67:143-53.<br \/><span class=\"ref ref5\">5.<\/span>\u00a0Schunk SJ, Kleber ME, M\u00e4rz W, et al. Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J 2021: doi: 10.1093\/eurheartj\/ehab107. Online ahead of print.<br \/><span class=\"ref ref6\">6.<\/span>\u00a0Papac-Milicevic N, J Binder CJ. Can a single genetic variant explain residual cardiovascular risk by modifying NLRP3 expression? Eur Heart J 2021; doi: 10.1093\/eurheartj\/ehab201. Online ahead of print.<br \/><span class=\"ref ref7\">7.<\/span>\u00a0Johannesen CDL, Mortensen MB, Langsted A, Nordestgaard BG. Apolipoprotein B and non-HDL cholesterol better reflect residual risk than LDL cholesterol in statin-treated patients. J Am Coll Cardiol 2021;77:1439-50.<br \/><span class=\"ref ref8\">8.<\/span>\u00a0Sniderman AD, Islam S, Yusuf S, McQueen MJ. Discordance analysis of Apolipoprotein B and non-high density lipoprotein cholesterol as markers of cardiovascular risk in the INTERHEART study. Atherosclerosis 2012;225:444-9.<br \/><span class=\"ref ref9\">9.<\/span>\u00a0Boekholdt SM, Arsenault BJ, Mora S, et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA 2012;307:1302-9.<br \/><span class=\"ref ref10\">10.<\/span>\u00a0Mach F, Baigent C, Catapano AL, et al. 2019 ESC\/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J 2020;41:111\u201388.<\/div>\n<\/li>\n<\/ol>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R3i \u7de8\u96c6\u8a18\u4e8b2021\u5e745\u6708 \u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\uff1a\u3069\u306e\u3088\u3046\u306b\u7279\u5b9a\u3059\u308b\u304b\uff1f Prof. Jean Charles [&hellip;]<\/p>\n","protected":false},"author":258497324,"featured_media":0,"parent":254286,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-254530","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u8ad6\u8aac 05\/21 - \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u6b8b\u5b58\uff1a\u3069\u306e\u3088\u3046\u306b\u8b58\u5225\u3059\u308b\u304b\uff1f - R3I<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u8ad6\u8aac 05\/21 - \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u6b8b\u5b58\uff1a\u3069\u306e\u3088\u3046\u306b\u8b58\u5225\u3059\u308b\u304b\uff1f - R3I\" \/>\n<meta property=\"og:description\" content=\"R3i \u7de8\u96c6\u8a18\u4e8b2021\u5e745\u6708 \u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\uff1a\u3069\u306e\u3088\u3046\u306b\u7279\u5b9a\u3059\u308b\u304b\uff1f Prof. Jean Charles [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\/\" \/>\n<meta property=\"og:site_name\" content=\"R3I\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-22T16:18:28+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data1\" content=\"4\u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\\\/\",\"url\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\\\/\",\"name\":\"\u8ad6\u8aac 05\\\/21 - \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u6b8b\u5b58\uff1a\u3069\u306e\u3088\u3046\u306b\u8b58\u5225\u3059\u308b\u304b\uff1f - R3I\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/#website\"},\"datePublished\":\"2024-12-30T17:21:54+00:00\",\"dateModified\":\"2025-02-22T16:18:28+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\\\/#breadcrumb\"},\"inLanguage\":\"ja\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e8%ab%96%e8%aa%ac-05-21-%e5%bf%83%e8%a1%80%e7%ae%a1%e7%b3%bb%e3%83%aa%e3%82%b9%e3%82%af%e3%81%ae%e6%ae%8b%e5%ad%98%ef%bc%9a%e3%81%a9%e3%81%ae%e3%82%88%e3%81%86%e3%81%ab%e8%ad%98%e5%88%a5%e3%81%99\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/r3i.org\\\/ja\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R3i\u793e\u8aac\",\"item\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"\u8ad6\u8aac 05\\\/21 &#8211; 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