{"id":254518,"date":"2024-12-27T18:50:26","date_gmt":"2024-12-27T17:50:26","guid":{"rendered":"https:\/\/r3i.org\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\/"},"modified":"2025-02-22T16:19:42","modified_gmt":"2025-02-22T15:19:42","slug":"%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\/","title":{"rendered":"\u793e\u8aac 04\/23 &#8211; 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center;\"><span>2023\u5e74\u306b\u304a\u3051\u308b\u6b8b\u5b58\u30ea\u30b9\u30af\uff1a\u3069\u3053\u306b\u5411\u304b\u3046\u3079\u304d\u304b\uff1f<\/span><\/h5>\n<h6 style=\"text-align: center;\">Prof. Jean Charles Fruchart, Prof. Michel Hermans, Prof. Pierre Amarenco<br \/>\u7de8\u96c6\u30c7\u30b9\u30af\u304b\u3089<\/h6>\n<p><span>\u5fc3\u8840\u7ba1\u75be\u60a3\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306f\u6982\u5ff5\uff081\uff09\u304b\u3089\u78ba\u7acb\u3055\u308c\u305f\u6a19\u7684\u3078\u3068\u9032\u5316\u3057\u3066\u3044\u308b\u3002\u6700\u8fd1\u306e\u7814\u7a76\u3001\u7279\u306b\u8102\u8cea\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u7814\u7a76\u3067\u306f\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u4f4e\u4e0b\u6cbb\u7642\u306b\u3088\u3063\u3066\u3001\u8133\u5352\u4e2d\u3092\u542b\u3080\u4e3b\u8981\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\uff082,3\uff09\u3002\u305d\u306e\u4ed6\u306e\u8102\u8cea\u30d1\u30e9\u30e1\u30fc\u30bf\u3001\u3068\u308a\u308f\u3051\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9rich\u30ea\u30dd\u86cb\u767d\uff08\u81e8\u5e8a\u73fe\u5834\u3067\u306f\u8840\u6f3f\u4e2d\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u30b5\u30ed\u30b2\u30fc\u30c8\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u4f7f\u7528\uff09\uff084\uff09\u304a\u3088\u3073\u30ea\u30dd\u86cb\u767d\uff08a\uff09\uff085\uff09\u306e\u6cbb\u7642\u6a19\u7684\u3068\u3057\u3066\u306e\u53ef\u80fd\u6027\u306b\u3082\u5927\u304d\u306a\u95a2\u5fc3\u304c\u5bc4\u305b\u3089\u308c\u3066\u3044\u308b\u3002\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9rich\u30ea\u30dd\u86cb\u767d\u306b\u3064\u3044\u3066\u306f\u3001\u9ad8\u7528\u91cf\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u3092\u7528\u3044\u305f1\u8a66\u9a13\uff08REDUCE-IT\uff09\u3067\u6709\u671b\u306a\u6210\u7e3e\u304c\u5f97\u3089\u308c\u3066\u304a\u308a\uff086\uff09\u3001\u540c\u8a66\u9a13\u306e\u7d50\u679c\u3092\u53d7\u3051\u3001\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306eTG\u9ad8\u5024\u306e\u7ba1\u7406\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u63a8\u5968\u4e8b\u9805\u304c\u5909\u66f4\u3055\u308c\u305f\u3002\u3057\u304b\u3057\u3001REDUCE-IT\u3067\u8a8d\u3081\u3089\u308c\u305f\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u76f8\u5bfe\u30ea\u30b9\u30af\u4f4e\u4e0b\u304c\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306b\u3088\u308bTG\u4f4e\u4e0b\u306e\u7a0b\u5ea6\u3068\u76f8\u95a2\u3057\u306a\u304b\u3063\u305f\u3053\u3068\u306f\u3001\u59a5\u5f53\u306a\u7d50\u679c\u3067\u3042\u308b\uff086\uff09\u3002\u3055\u3089\u306b\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9rich\u30ea\u30dd\u86cb\u767d\u5024\u306e\u8abf\u7bc0\u306f\u8907\u96d1\u3067\u3042\u308b\u3053\u3068\u304b\u3089\uff084\uff09\u3001REDUCE-IT\u4ee5\u5916\u306e\u8a66\u9a13\u3067\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3053\u3068\u306f\u3001\u304a\u305d\u3089\u304f\u9a5a\u304f\u3079\u304d\u3053\u3068\u3067\u306f\u306a\u3044\uff087,8\uff09\u3002\u30e1\u30f3\u30c7\u30eb\u7121\u4f5c\u70ba\u5316\u7814\u7a76\u306e\u77e5\u898b\uff089\uff09\u3092\u4e3b\u306a\u6839\u62e0\u3068\u3057\u3066TG\u9ad8\u5024\u306e\u662f\u6b63\u3092\u76ee\u6307\u3059\u65b0\u898f\u306e\u6cbb\u7642\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u958b\u767a\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u308a\u3001TG\u4f4e\u4e0b\u3068\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u3092\u8a73\u7d30\u306b\u691c\u8a0e\u3059\u308b\u6a5f\u4f1a\u304c\u5f97\u3089\u308c\u308b\u3002\u3055\u3089\u306b\u3001\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u9ad8\u5024\u306e\u662f\u6b63\u306b\u3088\u3063\u3066\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3064\u3044\u3066\u306f\u3001\u73fe\u5728\u9032\u884c\u4e2d\u306eLp(a) HORIZON\u8a66\u9a13\u306e\u7d50\u679c\u304c\u5f85\u305f\u308c\u308b\u3068\u3053\u308d\u3067\u3042\u308b\uff0810\uff09\u3002<\/span><\/p>\n<p><span>\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u306f\u591a\u304f\u306e\u56e0\u5b50\u304c\u95a2\u4e0e\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u305d\u306e\u4ed6\u306e\u6a19\u7684\u3082\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002CANTOS\uff08Canakinumab Anti-inflammatory Thrombosis Outcomes Study\uff09\u306f\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3\uff08IL\uff09-1\u03b2\u3092\u6a19\u7684\u3068\u3059\u308b\u5b8c\u5168\u30d2\u30c8\u5316\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3042\u308b\u30ab\u30ca\u30ad\u30cc\u30de\u30d6\u306b\u3088\u308b\u6297\u708e\u75c7\u6cbb\u7642\u306b\u3088\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u6700\u5584\u306e\u6cbb\u7642\uff08LDL-C\u5024\u306e\u5341\u5206\u306a\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u542b\u3080\uff09\u3092\u53d7\u3051\u3066\u3044\u308b\u60a3\u8005\u306e\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3044\u3046proof of concept\uff08\u6982\u5ff5\u5b9f\u8a3c\uff09\u3092\u793a\u3057\u305f\u30e9\u30f3\u30c9\u30de\u30fc\u30af\u8a66\u9a13\u3067\u3042\u3063\u305f\uff0811\uff09\u3002TG\u5024\u306e\u662f\u6b63\u3092\u8a55\u4fa1\u3057\u305f\u8a66\u9a13\u3068\u540c\u69d8\u3001\u6297\u708e\u75c7\u6cbb\u7642\u3092\u8a55\u4fa1\u3057\u305f\u8a66\u9a13\u3067\u3082\u3001\u3059\u3079\u3066\u306e\u8a66\u9a13\u3067\u6709\u671b\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u305f\u308f\u3051\u3067\u306f\u306a\u304b\u3063\u305f\u3002\u4f8b\u3048\u3070\u3001\u5fc3\u7b4b\u6897\u585e\u307e\u305f\u306f\u591a\u679d\u51a0\u52d5\u8108\u75be\u60a3\u306e\u65e2\u5f80\u3092\u6709\u3059\u308b2\u578b\u7cd6\u5c3f\u75c5\u307e\u305f\u306f\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u60a3\u80053,000\u4f8b\u3092\u5bfe\u8c61\u3068\u3057\u3066\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u306e\u52b9\u679c\u3092\u691c\u8a0e\u3057\u305fCIRT\uff08Cardiovascular Inflammation 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a13\u30c7\u30b6\u30a4\u30f3\u3082\u9032\u6b69\u3057\u3064\u3064\u3042\u308b\u3002Residual Risk Reduction Initiative\u306f\u3001\u6b8b\u5b58\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u3092\u76ee\u7684\u3068\u3059\u308b\u63a2\u7d22\u306b\u304a\u3044\u3066\u3001\u6d3b\u6c17\u306b\u6e80\u3061\u305f1\u5e74\u3068\u306a\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u3044\u308b\u3002<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;8px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"font-weight: 400;\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ol>\n<li style=\"font-weight: 400;\"><span>Fruchart JC, Sacks F, Hermans MP, et al. The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia. Am J Cardiol 2008;102(10 Suppl):1K-34K.<\/span><br \/><span class=\"ref ref2\">2.<\/span><span>\u00a0Sabatine MS, Giugliano RP, Keech AC, et al. Evolocumab and clinical outcomes in patients with cardiovascular disease. N Engl J Med 2017; 376:1713\u201322.<\/span><br \/><span class=\"ref ref3\">3.<\/span><span>\u00a0Schwartz GG, Steg PG, Szarek M, et al. Alirocumab and cardiovascular outcomes after acute coronary syndrome. N Engl J Med 2018;379:2097\u2013107.<\/span><br \/><span class=\"ref ref4\">4.<\/span><span>\u00a0Ginsberg HN, Packard CJ, Chapman MJ, et al. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society. Eur Heart J 2021;42:4791-806.<\/span><br \/><span class=\"ref ref5\">5.<\/span><span>\u00a0Kronenberg F, Mora S, Stroes ESG, et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J 2022;43:3925-46.<\/span><br \/><span class=\"ref ref6\">6.<\/span><span>\u00a0Bhatt DL, Steg PG, Miller M, et al. Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia. N Engl J Med 2019;380:11-22.<\/span><\/li>\n<\/ol>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R3i\u793e\u8aac2023\u5e744\u6708 2023\u5e74\u306b\u304a\u3051\u308b\u6b8b\u5b58\u30ea\u30b9\u30af\uff1a\u3069\u3053\u306b\u5411\u304b\u3046\u3079\u304d\u304b\uff1f Prof. Jean Charl [&hellip;]<\/p>\n","protected":false},"author":258497324,"featured_media":0,"parent":254286,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-254518","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u793e\u8aac 04\/23 - 2023\u5e74\u306e\u6b8b\u7559\u30ea\u30b9\u30af\uff1a\u3069\u3053\u3078\u5411\u304b\u3046\u306e\u304b\uff1f - R3I<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u793e\u8aac 04\/23 - 2023\u5e74\u306e\u6b8b\u7559\u30ea\u30b9\u30af\uff1a\u3069\u3053\u3078\u5411\u304b\u3046\u306e\u304b\uff1f - R3I\" \/>\n<meta property=\"og:description\" content=\"R3i\u793e\u8aac2023\u5e744\u6708 2023\u5e74\u306b\u304a\u3051\u308b\u6b8b\u5b58\u30ea\u30b9\u30af\uff1a\u3069\u3053\u306b\u5411\u304b\u3046\u3079\u304d\u304b\uff1f Prof. Jean Charl [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\/\" \/>\n<meta property=\"og:site_name\" content=\"R3I\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-22T15:19:42+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data1\" content=\"4\u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\\\/\",\"url\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\\\/\",\"name\":\"\u793e\u8aac 04\\\/23 - 2023\u5e74\u306e\u6b8b\u7559\u30ea\u30b9\u30af\uff1a\u3069\u3053\u3078\u5411\u304b\u3046\u306e\u304b\uff1f - R3I\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/#website\"},\"datePublished\":\"2024-12-27T17:50:26+00:00\",\"dateModified\":\"2025-02-22T15:19:42+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\\\/#breadcrumb\"},\"inLanguage\":\"ja\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/%e7%a4%be%e8%aa%ac-04-23-2023%e5%b9%b4%e3%81%ae%e6%ae%8b%e7%95%99%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e3%81%a9%e3%81%93%e3%81%b8%e5%90%91%e3%81%8b%e3%81%86%e3%81%ae%e3%81%8b%ef%bc%9f\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/r3i.org\\\/ja\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R3i\u793e\u8aac\",\"item\":\"https:\\\/\\\/r3i.org\\\/ja\\\/r3i%e7%a4%be%e8%aa%ac\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"\u793e\u8aac 04\\\/23 &#8211; 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