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\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u306f\u3001\u7a7a\u8179\u6642\u306b\u306f\u8d85\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u3068\u4e2d\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u304b\u3089\u306a\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u591a\u304f\u542b\u3080\u30ea\u30dd\u86cb\u767d\u3001\u975e\u7a7a\u8179\u6642\u306b\u306f\u3053\u308c\u3089\u4e21\u30ea\u30dd\u86cb\u767d\u3068\u30ab\u30a4\u30ed\u30df\u30af\u30ed\u30f3\u6b8b\u7559\u7269\u304b\u3089\u306a\u308b\u30ea\u30dd\u86cb\u767d\u306b\u542b\u307e\u308c\u308b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u3053\u3068\u3067\u3042\u308b\u3002\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb-LDL-C-HDL-C\u3067\u8a08\u7b97\u3055\u308c\u308b\u3002 <\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_font_size=&#8221;8px&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p style=\"font-weight: 400;\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<ol>\n<li style=\"font-weight: 400;\"><span>Sabatine M\u3001Giugliano R\u3001Wiviott S\u3001\u4ed6\uff1a\u8102\u8cea\u3068\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u6e1b\u5c11\u306b\u304a\u3051\u308b\u30a8\u30dc\u30ed\u30af\u30de\u30d6\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3002New Engl J Med 2015; Published online 15 March, DOI:10.1056\/NEJMoa1500858.  <\/span><br \/><span class=\"ref ref2\">2.<\/span><span> Robinson J, Farnier M, Krempf M et al; Efficacy and safety of alirocumab in reducing lipids and cardiovascular events.New Engl J Med 2015; \u30aa\u30f3\u30e9\u30a4\u30f3\u72483\u670815\u65e5\u767a\u884c, DOI: 10.1056\/MEJMoa1501031 <\/span><br \/><span class=\"ref ref3\">3.<\/span><span> Raal FJ, Giugliano RP, Sabatine MS et al. PCSK9\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u30a8\u30dc\u30ed\u30af\u30de\u30d6\uff08AMG 145\uff09\u306b\u3088\u308b\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u306e\u6e1b\u5c11\uff1a4\u3064\u306e\u7b2cII\u76f8\u8a66\u9a13\u306b\u304a\u3051\u308b1,300\u4eba\u4ee5\u4e0a\u306e\u60a3\u8005\u306e\u30d7\u30fc\u30eb\u89e3\u6790\u3002J Am Coll Cardiol 2014;63:1278-88.  <\/span><br \/><span class=\"ref ref4\">4.<\/span><span> Khera AV, Everett BM, Caulfield MP et al. \u30ea\u30dd\u86cb\u767d\uff08a\uff09\u6fc3\u5ea6\u3001\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3001\u6b8b\u5b58\u8840\u7ba1\u30ea\u30b9\u30af\uff1aJUPITER\u8a66\u9a13\uff08Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin\uff09\u306e\u89e3\u6790\u3002Circulation 2014;129:635-42.  <\/span><br \/><span class=\"ref ref5\">5.<\/span><span> Varbo A, Freiberg J, Nordestgaard B. 90,000\u4eba\u306e\u4e00\u822c\u96c6\u56e3\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u75be\u60a3\u304a\u3088\u3073\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306e\u5bc4\u4e0e\u56e0\u5b50\u3068\u3057\u3066\u306e\u6975\u7aef\u306a\u975e\u671d\u98df\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb vs \u6975\u7aef\u306aLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3002Clin Chem2015;61:533-543. <\/span><br \/><span class=\"ref ref6\">6.<\/span><span> Nordestgaard BG, Varbo A. \u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3068\u5fc3\u8840\u7ba1\u75be\u60a3\u3002Lancet 2014;384:626-35. <\/span><\/li>\n<\/ol>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R3i\u793e\u8aac\u6b8b\u7559\u30ea\u30b9\u30af\u8ad6\u4e89\u306e\u706b\u7a2e\uff1aLDL-C\u3092\u4e0b\u3052\u308b\u304b\u3001\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4e0b\u3052\u308b\u304b\uff1f \u30df\u30b7\u30a7\u30eb\u30fb\u30a8\u30eb\u30de\u30f3\u30b9\u6559\u6388 [&hellip;]<\/p>\n","protected":false},"author":258497324,"featured_media":0,"parent":254286,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_crdt_document":"","jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-254506","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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