{"id":254491,"date":"2025-01-04T17:28:45","date_gmt":"2025-01-04T16:28:45","guid":{"rendered":"https:\/\/r3i.org\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-03-15-%e8%84%b3%e5%8d%92%e4%b8%ad%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b\/"},"modified":"2025-02-16T22:56:29","modified_gmt":"2025-02-16T21:56:29","slug":"%e7%a4%be%e8%aa%ac-03-15-%e8%84%b3%e5%8d%92%e4%b8%ad%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/r3i%e7%a4%be%e8%aa%ac\/%e7%a4%be%e8%aa%ac-03-15-%e8%84%b3%e5%8d%92%e4%b8%ad%e3%81%b8%e3%81%ae%e5%af%be%e7%ad%96%e3%82%92%e6%b1%82%e3%82%81%e3%82%8b\/","title":{"rendered":"\u793e\u8aac 03\/15 – \u8133\u5352\u4e2d\u3078\u306e\u5bfe\u7b56\u3092\u6c42\u3081\u308b"},"content":{"rendered":"

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R3i\u793e\u8aac<\/h2>\n

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\u4eca\u6708\u306eLandmark\u8a66\u9a13\u3067\u53d6\u308a\u4e0a\u3052\u305fPERFORM\u8a66\u9a13\uff08\u865a\u8840\u6027\u8133\u5352\u4e2d\u307e\u305f\u306f\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\u306e\u65e2\u5f80\u306e\u3042\u308b\u60a3\u8005\u306b\u304a\u3051\u308b\u30c6\u30eb\u30c8\u30ed\u30d0\u30f3\u306b\u3088\u308b\u865a\u8840\u6027\u8133\u8840\u7ba1\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u4e88\u9632\uff09\u304a\u3088\u3073SPARCL\u8a66\u9a13\uff08\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u7a4d\u6975\u7684\u4f4e\u4e0b\u306b\u3088\u308b\u8133\u5352\u4e2d\u4e88\u9632\uff09\u306e\u6700\u8fd1\u306e\u89e3\u6790\u306f\u3001\u3053\u306e\u4e00\u9023\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u52a0\u3048\u3066\u3044\u308b\u3002<\/span>4<\/sup> \u4f4eHDL-C\uff0840mg\/dL\u307e\u305f\u306f1.01mmol\/L\uff09\u3068\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08150mg\/dL\u307e\u305f\u306f1.7mmol\/L\uff09\u3068\u5b9a\u7fa9\u3055\u308c\u308b\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u306f\u3001\u8133\u5352\u4e2d\u307e\u305f\u306f\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\uff08TIA\uff09\u306e\u65e2\u5f80\u304c\u3042\u308a\u3001\u30b9\u30bf\u30c1\u30f3\u3092\u542b\u3080\u6700\u5584\u306e\u5185\u79d1\u7684\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u6b8b\u5b58\u3055\u305b\u308b\u91cd\u8981\u306a\u8981\u56e0\u3067\u3042\u3063\u305f\u3002\u4e21\u8a66\u9a13\u306b\u304a\u3044\u3066\uff0cLDL-C\u3092\u542b\u3080\u4ed6\u306e\u5fc3\u8840\u7ba1\u5371\u967a\u56e0\u5b50\u304c\u6700\u5584\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u6cbb\u7642\u306b\u3088\u3063\u3066\u5341\u5206\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\uff0c\u3053\u306e\u8102\u8cea\u7570\u5e38\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6709\u3059\u308b\u60a3\u8005\u3067\u306f\u8133\u5352\u4e2d\u306e\u518d\u767a\u30ea\u30b9\u30af\u304c36\u301c40\uff05\u5897\u52a0\u3057\u305f\u3002 <\/span><\/p>\n

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\u53c2\u8003\u6587\u732e<\/strong><\/p>\n

    \n
  1. Mozaffarian D, Benjamin EJ, Go AS, et al. \u5fc3\u81d3\u75c5\u3068\u8133\u5352\u4e2d\u306e\u7d71\u8a08-2015\u5e74\u6700\u65b0\u7248\uff1a\u7c73\u56fd\u5fc3\u81d3\u5354\u4f1a\u304b\u3089\u306e\u5831\u544a\u3002Circulation.2015 ;e29-322. <\/span>
    2.<\/span> Park JH, Lee J, Ovbiagele B. \u975e\u4f1d\u7d71\u7684\u8840\u6e05\u8102\u8cea\u5909\u6570\u3068\u8133\u5352\u4e2d\u518d\u767a\u30ea\u30b9\u30af\u3002Stroke 2014;45:3269-74. <\/span>
    3.<\/span> \u9589\u7d4c\u5f8c\u5973\u6027\u306b\u304a\u3051\u308b\u8102\u8cea\u30fb\u30ea\u30dd\u86cb\u767d\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u865a\u8840\u6027\u8133\u5352\u4e2d\u30ea\u30b9\u30af\u3002Stroke 2012;43:958-66. <\/span>
    4.<\/span> Sirimarco G, Labreuche J, Bruckert E et al; PERFORM\u3068SPARCL\u306e\u7814\u7a76\u8005\u3068\u59d4\u54e1\u4f1a\u3092\u4ee3\u8868\u3057\u3066\u3002\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3051\u308b\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u3068\u6b8b\u5b58\u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u3002Stroke 2014;45:1429-36. <\/span>
    5.<\/span> Arsenault BJ\uff0cBarter P\uff0cDeMicco DA\u3089\uff1bTreating to New Targets\uff08TNT\uff09\u7814\u7a76\u8005\u3002\u8102\u8cea\u304a\u3088\u3073\u975e\u8102\u8cea\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306b\u3088\u308b\u3001treating to new targets\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u5b89\u5b9a\u51a0\u52d5\u8108\u60a3\u8005\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u4e88\u6e2c\u3002PLoS One 2014;9(12):e114519. <\/span>
    6.<\/span> Nordestgaard BG, Chapman MJ, Ray K, et al. \u5fc3\u8840\u7ba1\u7cfb\u5371\u967a\u56e0\u5b50\u3068\u3057\u3066\u306e\u30ea\u30dd\u86cb\u767d(a)\uff1a\u73fe\u72b6\u3002Eur Heart J 2010;31:2844-53 <\/span>
    7.<\/span> Raal FJ, Giugliano RP, Sabatine MS et al. PCSK9\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u30a8\u30dc\u30ed\u30af\u30de\u30d6\uff08AMG 145\uff09\u306b\u3088\u308b\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u306e\u6e1b\u5c11\uff1a4\u3064\u306e\u7b2cII\u76f8\u8a66\u9a13\u306e1,300\u4eba\u4ee5\u4e0a\u306e\u60a3\u8005\u306e\u30d7\u30fc\u30eb\u89e3\u6790\u3002J Am Coll Cardiol 2014;63(13):1278-88. <\/span><\/li>\n<\/ol>\n

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