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\u3057\u304b\u3057\u3001\u3053\u306e\u5fc3\u8840\u7ba1\u7cfb\u3078\u306e\u6709\u76ca\u6027\u306f\u3001\u90e8\u5206\u7684\u306b\u306fTG\u4f4e\u4e0b\u4ee5\u5916\u306e\u52b9\u679c\u306b\u8d77\u56e0\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u5ff5\u982d\u306b\u7f6e\u304f\u3053\u3068\u304c\u91cd\u8981\u3067\u3042\u308b\u3002REDUCE-IT\u304b\u3089\u5f97\u3089\u308c\u305f2\u3064\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3053\u308c\u3092\u88cf\u4ed8\u3051\u3066\u3044\u308b\u3002\u7b2c\u4e00\u306b\u3001REDUCE-IT\u306b\u304a\u3051\u308bTG\u4f4e\u4e0b\u306e\u5927\u304d\u3055\uff08\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u30891\u5e74\u5f8c\u307e\u3067\u306e\u6e1b\u5c11\u306e\u4e2d\u592e\u502418.3\uff05\u300139.0mg\/dL\uff09\u306f\u3001\u5fc3\u8840\u7ba1\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306b\u57fa\u3065\u304f\u671f\u5f85\u5024\u3088\u308a\u3082\u5c0f\u3055\u304b\u3063\u305f\u3053\u3068\u3067\u3042\u308b\u3002 <\/span>7<\/sup>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u85ac\u7406\u5b66\u306b\u95a2\u3059\u308b\u73fe\u5728\u306e\u77e5\u898b\u306b\u57fa\u3065\u3051\u3070\u3001\u3053\u308c\u3089\u306e\u975e\u8102\u8cea\u4f5c\u7528\u306e\u5019\u88dc\u3068\u3057\u3066\u306f\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3001\u6297\u4e0d\u6574\u8108\u4f5c\u7528\u3001\u6297\u8840\u6813\u4f5c\u7528\u306a\u3069\u304c\u8003\u3048\u3089\u308c\u308b\u3002<\/span>8<\/sup><\/span><\/p>\n

STRENGTH\u306e\u7d50\u679c\u304c\u306a\u3044\u4ee5\u4e0a\u3001\u3053\u308c\u3089\u306e\u8aac\u660e\u306f\u63a8\u6e2c\u306e\u57df\u3092\u51fa\u306a\u3044\u3002\u81e8\u5e8a\u533b\u306f\u3001\u81ea\u5206\u306a\u308a\u306e\u7d50\u8ad6\u3092\u51fa\u3059\u305f\u3081\u306b\u3001STRENGTH\u306e\u30c7\u30fc\u30bf\u306e\u516c\u8868\u3092\u5fc3\u5f85\u3061\u306b\u3057\u3066\u3044\u308b\u3053\u3068\u3060\u308d\u3046\u3002 <\/span><\/p>\n

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\u53c2\u8003\u6587\u732e<\/strong><\/p>\n

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  1. Bhatt DL\u3001Steg PG\u3001Miller M\u3001\u4ed6\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u3002N Engl J Med 2019;380:11-22. <\/span>
    2.<\/span> Bhatt DL\u3001Steg PG\u3001Miller M\u3001\u4ed6\uff1a\u7dcf\u865a\u8840\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u52b9\u679c\uff1aREDUCE-IT\u3088\u308a\u3002J Am Coll Cardiol 2019;73:2791-802. <\/span>
    3.<\/span> \u6df7\u5408\u578b\u8102\u8cea\u7570\u5e38\u75c7\u3092\u5bfe\u8c61\u3068\u3057\u305f Epanova \u306e\u7b2c III \u76f8 STRENGTH \u8a66\u9a13\u306e\u6700\u65b0\u60c5\u5831\u3002\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9 2020\u5e741\u670813\u65e5     https:\/\/www.astrazeneca.com\/media-centre\/press-releases\/2020\/update-on-phase-iii-strength-trial-for-epanova-in-mixed-dyslipidaemia-13012020.html<\/a> <\/span>
    4.<\/span> Nicholls SJ, Lincoff AM, Bash D, et al. \u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u9ad8\u5024\u3001\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u5024\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3051\u308b\u30aa\u30e1\u30ac3\u30ab\u30eb\u30dc\u30f3\u9178\u306e\u8a55\u4fa1\uff1aSTRENGTH\u8a66\u9a13\u306e\u6839\u62e0\u3068\u30c7\u30b6\u30a4\u30f3\u3002Clin Cardiol 2018;41:1281-8. <\/span>
    5.<\/span> Aung T, Halsey J, Kromhout D, et al. \u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u4f7f\u7528\u3068\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\uff1a77 917\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f10\u8a66\u9a13\u306e\u30e1\u30bf\u89e3\u6790\u3002JAMA Cardiol 2018;3:225-34. <\/span>
    6.<\/span> Hu Y, Hu FB, Manson JE.\u6d77\u6d0b\u6027\u30aa\u30e1\u30ac3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u5fc3\u8840\u7ba1\u75be\u60a3\uff1a127 477\u4eba\u306e\u53c2\u52a0\u8005\u3092\u542b\u308013\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u6700\u65b0\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3002J Am Heart Assoc 2019;8 <\/span>19<\/sup>:e0135<\/span>43.<\/span> <\/span>
    7.<\/span> Bhatt DL\u3001Steg PG\u3001Miller M\u3001\u4ed6\uff1a\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4e09\u5206\u4f4d\u3092\u8d85\u3048\u305f\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u521d\u56de\u304a\u3088\u3073\u5168\u865a\u8840\u30a4\u30d9\u30f3\u30c8\u306e\u6e1b\u5c11\u3002J Am Coll Cardiol 2019;74:1159-61. <\/span>
    8.<\/span> Boden WE, Bhatt DL, Toth PP, et al. REDUCE-IT\u8a66\u9a13\u306b\u304a\u3051\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u521d\u56de\u304a\u3088\u3073\u7dcf\u30a4\u30d9\u30f3\u30c8\u306e\u9855\u8457\u306a\u6e1b\u5c11\uff1a\u306a\u305c\u3053\u306e\u7d50\u679c\u304c\u8102\u8cea\u7570\u5e38\u75c7\u6cbb\u7642\u85ac\u306e\u65b0\u6642\u4ee3\u3092\u5207\u308a\u958b\u304f\u306e\u304b\u3002Eur Heart J 2019 ;doi: 10.1093\/eurheartj\/ehz778. [Epub ahead of print]<\/span><\/li>\n<\/ol>\n

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