{"id":254429,"date":"2025-01-23T23:43:45","date_gmt":"2025-01-23T22:43:45","guid":{"rendered":"https:\/\/r3i.org\/%e7%94%bb%e6%9c%9f%e7%9a%84-%e5%9b%bd%e9%9a%9b%e3%83%9d%e3%83%aa%e3%82%ad%e3%83%a3%e3%83%83%e3%83%97%e8%a9%a6%e9%a8%93-3%ef%bc%88tips-3%ef%bc%89%e3%81%a7%e3%80%81%e4%b8%80%e6%ac%a1%e4%ba%88%e9%98%b2\/"},"modified":"2025-02-16T22:46:07","modified_gmt":"2025-02-16T21:46:07","slug":"%e7%94%bb%e6%9c%9f%e7%9a%84-%e5%9b%bd%e9%9a%9b%e3%83%9d%e3%83%aa%e3%82%ad%e3%83%a3%e3%83%83%e3%83%97%e8%a9%a6%e9%a8%93-3%ef%bc%88tips-3%ef%bc%89%e3%81%a7%e3%80%81%e4%b8%80%e6%ac%a1%e4%ba%88%e9%98%b2","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e7%94%bb%e6%9c%9f%e7%9a%84-%e5%9b%bd%e9%9a%9b%e3%83%9d%e3%83%aa%e3%82%ad%e3%83%a3%e3%83%83%e3%83%97%e8%a9%a6%e9%a8%93-3%ef%bc%88tips-3%ef%bc%89%e3%81%a7%e3%80%81%e4%b8%80%e6%ac%a1%e4%ba%88%e9%98%b2\/","title":{"rendered":"\u753b\u671f\u7684-\u56fd\u969b\u30dd\u30ea\u30ad\u30e3\u30c3\u30d7\u8a66\u9a13-3\uff08TIPS-3\uff09\u3067\u3001\u4e00\u6b21\u4e88\u9632\u60a3\u8005\u306b\u304a\u3044\u3066\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u4f75\u7528\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;1px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_2_text_color=&#8221;gcid-primary-color&#8221; header_5_text_color=&#8221;gcid-secondary-color&#8221; text_orientation=&#8221;center&#8221; width=&#8221;99%&#8221; custom_margin=&#8221;|-147px||||&#8221; custom_padding=&#8221;|0px||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}&#8221; sticky_enabled=&#8221;0&#8243;]<h2><span>International Polycap Study-3\uff08TIPS-3\uff09\u3067\u306f\u3001\u4e00\u6b21\u4e88\u9632\u60a3\u8005\u306b\u304a\u3044\u3066\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u4f75\u7528\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/span><\/h2>\n<h5><span>2021\u5e743\u670822\u65e5<\/span><\/h5>\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\"><span>\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607\u3068\u9ad8\u8840\u5727\u3092\u6a19\u7684\u3068\u3057\u305f\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u4f75\u7528\u7642\u6cd5\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u65e2\u5f80\u306e\u306a\u3044\u4e2d\u7b49\u5ea6\u30ea\u30b9\u30af\u306e\u4eba\u306b\u304a\u3044\u3066\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u309231\uff05\u6e1b\u5c11\u3055\u305b\u305f\u3002<\/span><\/div>\n<div class=\"authors\"><span>Yusuf S, Joseph P, Dans A, et al. \u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u306e\u306a\u3044\u4eba\u306b\u304a\u3051\u308b\u30a2\u30b9\u30d4\u30ea\u30f3\u4f75\u7528\u307e\u305f\u306f\u975e\u4f75\u7528\u306e\u30dd\u30ea\u30d4\u30eb\u3002N Engl J Med 2021; 384:216-228.  <\/span><\/div>\n<div class=\"authors\"><span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"authors\">\n<p><strong>\u7814\u7a76\u6982\u8981<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div>\n<div>\n<div>\n<div>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\" width=\"17%\"><strong>\u76ee\u7684<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\" width=\"83%\">\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f340mg\uff0c\u30a2\u30c6\u30ce\u30ed\u30fc\u30eb100mg\uff0c\u30d2\u30c9\u30ed\u30af\u30ed\u30ed\u30c1\u30a2\u30b8\u30c925mg\uff0c\u30e9\u30df\u30d7\u30ea\u30eb10mg\u3092\u542b\u3080\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f375mg\u306e\u4f75\u7528\u307e\u305f\u306f\u975e\u4f75\u7528\u306b\u3088\u308a\uff0c\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u306a\u3044\u4e2d\u7b49\u5ea6\u30ea\u30b9\u30af\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u6e1b\u5c11\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3059\u308b\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3002\u540c\u610f\u5f8c\u3001\u9069\u683c\u88ab\u9a13\u8005\u306f3\u301c4\u9031\u9593\u306e\u30e9\u30f3\u30a4\u30f3\u30d5\u30a7\u30fc\u30ba\u3092\u53d7\u3051\u3001\u4f4e\u7528\u91cf\u30dd\u30ea\u30d4\u30eb\u3068\u4f4e\u7528\u91cf\u30a2\u30b9\u30d4\u30ea\u30f3\u3092\u6bce\u65e5\u6295\u4e0e\u3055\u308c\u305f\u3002\u8a66\u9a13\u85ac\u306b\u8010\u5bb9\u6027\u3092\u793a\u3057\u305f\u88ab\u9a13\u8005\u306f\u30012\u00d72\u00d72\u306e\u8981\u56e0\u8a08\u753b\u306b\u3088\u308a\u3001\u30dd\u30ea\u30d4\u30eb\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u9023\u65e5\u6295\u4e0e\u3001\u30a2\u30b9\u30d4\u30ea\u30f3\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u9023\u65e5\u6295\u4e0e\u3001\u30dd\u30ea\u30d4\u30eb\uff0b\u30a2\u30b9\u30d4\u30ea\u30f3\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u9023\u65e5\u6295\u4e0e\u306b\u7121\u4f5c\u70ba\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u3002\u7121\u4f5c\u70ba\u5272\u308a\u4ed8\u3051\u306f\u4e2d\u592e\u7121\u4f5c\u70ba\u5316\u30d7\u30ed\u30bb\u30b9\u3092\u7528\u3044\u3001\u65bd\u8a2d\u3054\u3068\u306b\u5c64\u5225\u5316\u3055\u308c\u305f\u3002\u88ab\u9a13\u8005\u306f6\u9031\u9593\u5f8c\u30013\u30f5\u6708\u5f8c\u30016\u30f5\u6708\u5f8c\u30019\u30f5\u6708\u5f8c\u30011\u5e74\u5f8c\u3001\u305d\u306e\u5f8c\u306f6\u30f5\u6708\u9593\u9694\u3067\u8a66\u9a13\u7d42\u4e86\u307e\u3067\u8ffd\u8de1\u3055\u308c\u305f\u3002    <\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td valign=\"top\" bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u5bfe\u8c61\u8005<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">50\u6b73\u4ee5\u4e0a\uff08\u7537\u6027\uff09\u304a\u3088\u307355\u6b73\u4ee5\u4e0a\uff08\u5973\u6027\uff09\u3067INTERHEART\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\u226710\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u306a\u3044\u88ab\u9a13\u8005\u3001\u307e\u305f\u306f65\u6b73\u4ee5\u4e0a\u3067INTERHEART\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\u22675\u306e\u7537\u5973\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u6210\u679c\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\n<p>&#8211; \u30dd\u30ea\u30d4\u30eb\u5358\u72ec\u3068\u30dd\u30ea\u30d4\u30eb\uff0b\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u6bd4\u8f03\u3067\u306f\u3001\u4e3b\u8981\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u5fc3\u8840\u7ba1\u7cfb\u306e\u539f\u56e0\u306b\u3088\u308b\u6b7b\u4ea1\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u8607\u751f\u5fc3\u505c\u6b62\u3001\u5fc3\u4e0d\u5168\u3001\u8840\u884c\u518d\u5efa\u8853\u306e\u8907\u5408\u3068\u3057\u305f\u3002<\/p>\n<p>&#8211; \u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u6bd4\u8f03\u3067\u306f\u3001\u4e3b\u8981\u8ee2\u5e30\u306f\u5fc3\u8840\u7ba1\u7cfb\u306e\u539f\u56e0\u306b\u3088\u308b\u6b7b\u4ea1\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3067\u3042\u3063\u305f\u3002<\/p>\n<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u65b9\u6cd5\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u672c\u8a66\u9a13\u306fintention-to-treat\u30d9\u30fc\u30b9\u3067\u89e3\u6790\u3055\u308c\u305f\u3002\u4e3b\u8981\u89e3\u6790\u306f\u3001Cox\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3001\u4e3b\u8981\u8ee2\u5e30\u30a4\u30d9\u30f3\u30c8\u304c\u78ba\u8a8d\u3055\u308c\u308b\u307e\u3067\u306e\u671f\u9593\u3068\u3057\u305f\u3002 <\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7d50\u679c<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\n<p>\u5408\u8a085713\u4eba\uff08\u5e73\u5747\u5e74\u9f6263.9\u6b73\u3001\u5973\u602753\uff05\uff09\u304c\u7121\u4f5c\u70ba\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u3002INTERHEART\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\u306e\u5e73\u5747\u306f16.8\u3067\u3042\u308a\u3001\u4e2d\u7b49\u5ea6\u30ea\u30b9\u30af\u306e\u96c6\u56e3\u3068\u4e00\u81f4\u3057\u305f\u3002\u307b\u3068\u3093\u3069\u306e\u88ab\u9a13\u8005\u304c\u30a4\u30f3\u30c9\uff0848\uff05\uff09\u3068\u30d5\u30a3\u30ea\u30d4\u30f3\uff0829\uff05\uff09\u3067\u52df\u96c6\u3055\u308c\u305f\u3002\u30dd\u30ea\u30d4\u30eb\uff08\u5358\u72ec\u307e\u305f\u306f\u30a2\u30b9\u30d4\u30ea\u30f3\u3068\u306e\u4f75\u7528\uff09\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u5358\u72ec\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3092\u301c19mg\/dL\u3001\u53ce\u7e2e\u671f\u8840\u5727\u30925.8mmHg\u4f4e\u4e0b\u3055\u305b\u305f\u3002   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   <\/p>\n<\/div>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr>\n<td valign=\"top\" bgcolor=\"#E9E9E9\" width=\"13%\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/td>\n<td valign=\"top\" bgcolor=\"#FFFFFF\" width=\"87%\">\n<p>1.Truelove M, Patel A, Bompoint S, et al. \u5fc3\u8840\u7ba1\u7cfb\u30dd\u30ea\u30d4\u30eb\u6226\u7565\u304c\u9320\u5264\u8ca0\u62c5\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3002Cardiovasc Ther 2015; 33:347-52.  <\/p>\n<p>2.Wald NJ, Law MR.\u5fc3\u8840\u7ba1\u75be\u60a3\u309280\uff05\u4ee5\u4e0a\u6e1b\u5c11\u3055\u305b\u308b\u6226\u7565\u3002BMJ 2003; 326:1419. <\/p>\n<p>3.\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\uff08WHO\uff09\u3002\u5fc3\u8840\u7ba1\u75be\u60a3\u3002\u30d5\u30a1\u30af\u30c8\u30b7\u30fc\u30c8\u3002https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cardiovascular-diseases-(cvds)   <\/p>\n<p>4.\u56fd\u969b\u30dd\u30ea\u30ad\u30e3\u30c3\u30d7\u8a66\u9a13-3\uff08TIPS-3\uff09\uff1a\u30c7\u30b6\u30a4\u30f3\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u7279\u5fb4\u3001\u5b9f\u65bd\u4e0a\u306e\u8ab2\u984c\u3002Am Heart J 2018; 206:72-79.  <\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" bgcolor=\"#E9E9E9\"><strong>\u30ad\u30fc\u30ef\u30fc\u30c9<\/strong><\/td>\n<td valign=\"top\" bgcolor=\"#FFFFFF\">\u30dd\u30ea\u30d4\u30eb\uff1b\u4e00\u6b21\u4e88\u9632\uff1b\u56fd\u969b\u30dd\u30ea\u30ad\u30e3\u30c3\u30d7\u8a66\u9a13-3\uff08TIPS-3\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>International Polycap Study-3\uff08TIPS-3\uff09\u3067\u306f\u3001\u4e00\u6b21\u4e88\u9632\u60a3\u8005\u306b\u304a\u3044\u3066\u30dd\u30ea\u30d4\u30eb\u3068 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