{"id":254423,"date":"2025-01-23T23:54:38","date_gmt":"2025-01-23T22:54:38","guid":{"rendered":"https:\/\/r3i.org\/%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-strength%ef%bc%9a%e3%82%aa%e3%83%a1%e3%82%ac3%e8%84%82%e8%82%aa%e9%85%b8%e3%81%ae%e4%b8%ad%e7%ab%8b%e7%9a%84%e3%82%a2%e3%82%a6%e3%83%88%e3%82%ab\/"},"modified":"2025-02-16T22:45:00","modified_gmt":"2025-02-16T21:45:00","slug":"%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-strength%ef%bc%9a%e3%82%aa%e3%83%a1%e3%82%ac3%e8%84%82%e8%82%aa%e9%85%b8%e3%81%ae%e4%b8%ad%e7%ab%8b%e7%9a%84%e3%82%a2%e3%82%a6%e3%83%88%e3%82%ab","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-strength%ef%bc%9a%e3%82%aa%e3%83%a1%e3%82%ac3%e8%84%82%e8%82%aa%e9%85%b8%e3%81%ae%e4%b8%ad%e7%ab%8b%e7%9a%84%e3%82%a2%e3%82%a6%e3%83%88%e3%82%ab\/","title":{"rendered":"\u30e9\u30f3\u30c9\u30de\u30fc\u30af-STRENGTH\uff1a\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u4e2d\u7acb\u7684\u30a2\u30a6\u30c8\u30ab\u30e0\u8a66\u9a13"},"content":{"rendered":"\n[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”1px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_2_text_color=”gcid-primary-color” header_5_text_color=”gcid-secondary-color” text_orientation=”center” width=”99%” custom_margin=”|-147px||||” custom_padding=”|0px||||” hover_enabled=”0″ global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}” sticky_enabled=”0″]

STRENGTH\uff1a\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u4e2d\u7acb\u7684\u30a2\u30a6\u30c8\u30ab\u30e0\u8a66\u9a13<\/span><\/h2>\n
4 2021\u5e741\u6708<\/span><\/h5>\n
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\u9ad8\u7528\u91cf\u306e\u30aa\u30e1\u30ac-3\u8102\u80aa\u9178\uff08\u30a8\u30a4\u30b3\u30b5\u30da\u30f3\u30bf\u30a8\u30f3\u9178\uff08EPA\uff09\u3068\u30c9\u30b3\u30b5\u30d8\u30ad\u30b5\u30a8\u30f3\u9178\uff08DHA\uff09\u306e\u30ab\u30eb\u30dc\u30f3\u9178\u88fd\u5264\uff09\u306e\u6295\u4e0e\u306f\u3001\u52d5\u8108\u786c\u5316\u6027\u8102\u8cea\u7570\u5e38\u75c7\u3067\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u3092\u6e1b\u5c11\u3055\u305b\u306a\u304b\u3063\u305f\u3002<\/span><\/div>\n
Nicholls SJ, Lincoff AM, Garcia M, et al. \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u9ad8\u7528\u91cf\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3068\u30b3\u30fc\u30f3\u6cb9\u306e\u6bd4\u8f03\u52b9\u679c\uff1aSTRENGTH Randomized Clinical Trial\u3002JAMA 2020; doi: 10.1001\/jama.2020.22258. <\/em><\/div>\n
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\u7814\u7a76\u6982\u8981<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\u76ee\u7684<\/strong><\/td>\nEPA\u3068DHA\u306e\u30ab\u30eb\u30dc\u30f3\u9178\u88fd\u5264\uff08omega-3 CA\uff09\u304c\u3001\u9ad8\u30ea\u30b9\u30af\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u60a3\u8005\u306e\u5fc3\u8840\u7ba1\u8ee2\u5e30\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u8a55\u4fa1\u3059\u308b\u3053\u3068\u3002<\/td>\n<\/tr>\n
\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a<\/strong><\/td>\n\u7121\u4f5c\u70ba\u4e8c\u91cd\u76f2\u691c\u591a\u65bd\u8a2d\u6bd4\u8f03\u8a66\u9a13\u3002\u5bfe\u8c61\u60a3\u8005\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u3092\u542b\u3080\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u305f\u6cbb\u7642\u306b\u52a0\u3048\u3066\u30014g\/\u65e5\u306e\u30aa\u30e1\u30ac3CA\u307e\u305f\u306f\u30b3\u30fc\u30f3\u6cb9\uff08\u3059\u306a\u308f\u3061\u3001\u4e0d\u6d3b\u6027\u6bd4\u8f03\u85ac\uff09\u3092\u6295\u4e0e\u3059\u308b\u7fa4\u306b\u7121\u4f5c\u70ba\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\uff081\uff1a1\uff09\u3002 <\/td>\n<\/tr>\n
\u7814\u7a76\u5bfe\u8c61\u8005\uff1a<\/strong><\/td>\n

\u6b73\u306e\u60a3\u8005 >18\u6b73\u3067\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u5024\u304c\u9ad8\u3044\u3002 <100 mg\/dL (<2.6mmol\/L\uff09\u307e\u305f\u306f\u6700\u5927\u8010\u5bb9\u91cf\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u53d7\u3051\u305f\u8005\uff1b\u304a\u3088\u3073\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\uff08\u3059\u306a\u308f\u3061\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u5024 [TG] 180\u304b\u3089 <500mg\/dL\u304a\u3088\u3073\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb [HDL-C] <\u7537\u602742mg\/dL\u307e\u305f\u306f <\u5973\u6027\u306f47mg\/dL\uff09\u3092\u9069\u683c\u3068\u3057\u305f\u3002\u9ad8\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3068\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u5b9a\u7fa9\u3055\u308c\u305f\uff1a <\/p>\n

– \u78ba\u7acb\u3057\u305f\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\uff08ASCVD\uff09\u306e\u5b58\u5728\uff1b<\/p>\n

– 1\u578b\u307e\u305f\u306f2\u578b\u7cd6\u5c3f\u75c5\u304b\u3064\u7537\u602740\u6b73\u4ee5\u4e0a\u3001\u5973\u602750\u6b73\u4ee5\u4e0a\u3067\u3001\u55ab\u7159\u3001\u9ad8\u8840\u5727\u3001\u9ad8\u611f\u5ea6CRP\uff08hs-CRP\uff092mg\/L\u4ee5\u4e0a\u3001\u307e\u305f\u306f\u4e2d\u7b49\u5ea6\u306e\u30a2\u30eb\u30d6\u30df\u30f3\u5c3f\u5897\u52a0\u306a\u3069\u306e\u5371\u967a\u56e0\u5b50\u30921\u3064\u4ee5\u4e0a\u6709\u3059\u308b\u8005\uff1b <\/p>\n

– \u7537\u6027\u3067\u306f50\u6b73\u4ee5\u4e0a\uff0c\u5973\u6027\u3067\u306f60\u6b73\u4ee5\u4e0a\u306e\u9ad8\u30ea\u30b9\u30af\u4e00\u6b21\u4e88\u9632\u60a3\u8005\u3067\u3042\u3063\u3066\uff0c\u5c11\u306a\u304f\u3068\u30821\u3064\u306e\u8ffd\u52a0\u5371\u967a\u56e0\u5b50\uff0c\u3059\u306a\u308f\u3061\uff0c\u65e9\u767a\u6027\u51a0\u52d5\u8108\u75be\u60a3\u306e\u5bb6\u65cf\u6b74\uff0c\u6162\u6027\u55ab\u7159\uff0chs-CRP\u50242mg\/L\u4ee5\u4e0a\uff0c\u814e\u6a5f\u80fd\u969c\u5bb3\uff0c\u307e\u305f\u306f\u51a0\u52d5\u8108\u30ab\u30eb\u30b7\u30a6\u30e0\u30b9\u30b3\u30a2>300 Agatston units\u3092\u6709\u3059\u308b\u60a3\u8005\u3002<\/td>\n<\/tr>\n

\u8a66\u9a13\u306e\u7d50\u679c<\/strong><\/td>\n\u4e3b\u8981\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u3001\u5fc3\u8840\u7ba1\u6b7b\u3001\u975e\u81f4\u6b7b\u7684\u5fc3\u7b4b\u6897\u585e\u3001\u975e\u81f4\u6b7b\u7684\u8133\u5352\u4e2d\u3001\u51a0\u52d5\u8108\u8840\u884c\u518d\u5efa\u8853\u3001\u5165\u9662\u3092\u8981\u3059\u308b\u4e0d\u5b89\u5b9a\u72ed\u5fc3\u75c7\u306e\u8907\u5408\u3068\u3057\u305f\u3002<\/td>\n<\/tr>\n
\u65b9\u6cd5\uff1a<\/strong><\/td>\n\n

-\u672c\u8a66\u9a13\u306f\u30011600\u306e\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u5224\u5b9a\u304c\u967d\u6027\u3067\u300113000\u4eba\u306e\u60a3\u8005\u3092\u767b\u9332\u3059\u308b\u3088\u3046\u306b\u30c7\u30b6\u30a4\u30f3\u3055\u308c\u3066\u304a\u308a\u3001omega-3 CA\u7fa4\u306b\u304a\u3051\u308b\u76f8\u5bfe\u30ea\u30b9\u30af\u306e15\uff05\u6e1b\u5c11\u3092\u691c\u51fa\u3059\u308b90\uff05\u306e\u691c\u51fa\u529b\u304c\u3042\u308b\u3002\u5b89\u5168\u6027\u89e3\u6790\u96c6\u56e3\u306f\u3001\u8a66\u9a13\u85ac\u3092\u5c11\u306a\u304f\u3068\u30821\u56de\u670d\u7528\u3057\u305f\u60a3\u8005\u3068\u5b9a\u7fa9\u3055\u308c\u305f\u3002\u30cf\u30b6\u30fc\u30c9\u6bd4\uff08HR\uff09\u304a\u3088\u307395\uff05\u4fe1\u983c\u533a\u9593\uff08Cis\uff09\u306e\u63a8\u5b9a\u5024\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u304a\u3088\u3073\u5730\u57df\u306b\u304a\u3051\u308b\u78ba\u7acb\u3055\u308c\u305f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u5171\u5909\u91cf\u3092\u7528\u3044\u305fCox\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u8a08\u7b97\u3055\u308c\u305f\u3002 <\/p>\n

 <\/p>\n<\/td>\n<\/tr>\n

\u7d50\u679c<\/strong><\/td>\n\n

\u672c\u8a66\u9a13\u306f\u3001\u7121\u4f5c\u70ba\u5316\u3055\u308c\u305f13,078\u4f8b\u306e\u60a3\u8005\uff08\u5404\u6cbb\u7642\u306b6539\u4f8b\u304c\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\uff09\u306b\u304a\u3044\u30661384\u306e\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u304c\u8a18\u9332\u3055\u308c\u305f\u5f8c\u3001\u72ec\u7acb\u30c7\u30fc\u30bf\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u59d4\u54e1\u4f1a\u306e\u52e7\u544a\u306b\u57fa\u3065\u304d\u3001\u7121\u76ca\u6027\u3092\u7406\u7531\u306b2020\u5e741\u67088\u65e5\u306b\u65e9\u671f\u7d42\u4e86\u3055\u308c\u305f\u3002<\/p>\n

\u5168\u4f53\u3068\u3057\u3066\u3001\u60a3\u8005\u96c6\u56e3\u306e\u5e73\u5747\u5e74\u9f62\u306f62.5\u6b73\u300135\uff05\u304c\u5973\u6027\u300170\uff05\u304c\u7cd6\u5c3f\u75c5\u300156\uff05\u304c\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306bASCVD\u304c\u78ba\u7acb\u3057\u3066\u3044\u305f\u3002\u60a3\u8005\u306e\u7d0450\uff05\u306f\u9ad8\u5f37\u5ea6\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u305f\u3002\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306e\u8102\u8cea\u4e2d\u592e\u5024\u306fLDL-C\u304c75mg\/dL\u3001TG\u304c240mg\/dL\u3001HDL-C\u304c36mg\/dL\u3067\u3042\u3063\u305f\u3002 <\/p>\n

\u30aa\u30e1\u30ac3 CA\u6295\u4e0e\u7fa4\u3067\u306fTG\u304c19\uff05\u6e1b\u5c11\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001\u30b3\u30fc\u30f3\u6cb9\u6bd4\u8f03\u7fa4\u3067\u306f0.9\uff05\u6e1b\u5c11\u3057\u305f\u3002\u4e3b\u8981\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u30aa\u30e1\u30ac-3 CA\u6295\u4e0e\u7fa4785\u4f8b\uff0812.0\uff05\uff09\u3068\u30b3\u30fc\u30f3\u6cb9\u6295\u4e0e\u7fa4795\u4f8b\uff0812.2\uff05\uff09\u3067\u767a\u751f\u3057\u305f\uff08HR 0.99 [95\uff05CI, 95\uff05CI 0.90-1.09; p= 0.84\uff09\u3002\u4ed6\u306e\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306b\u306f\u6709\u610f\u306a\u5f71\u97ff\u306f\u307f\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u30aa\u30e1\u30ac3 CA\u306b\u3088\u308b\u6cbb\u7642\u306f\u307e\u305f\u3001\u5fc3\u623f\u7d30\u52d5\u306e\u76f8\u5bfe\u30ea\u30b9\u30af\u309269\uff05\u5897\u52a0\u3055\u305b\u305f\uff08HR 1.69\u300195\uff05CI 1.29-2.21\u3001p<0.001\uff09\u3002 <\/p>\n

 <\/p>\n<\/td>\n<\/tr>\n

\u7d50\u8ad6<\/strong><\/td>\n\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30b3\u30fc\u30f3\u6cb9\u3068\u6bd4\u8f03\u3057\u305f\u30aa\u30e1\u30ac-3 CA\u306e\u901a\u5e38\u306e\u80cc\u666f\u7642\u6cd5\u3078\u306e\u8ffd\u52a0\u306f\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u8907\u5408\u8ee2\u5e30\u306b\u6709\u610f\u5dee\u3092\u3082\u305f\u3089\u3055\u306a\u304b\u3063\u305f\u3002\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u3001\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u305f\u3081\u306b\u3053\u306e\u30aa\u30e1\u30ac-3\u8102\u80aa\u9178\u88fd\u5264\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3002 <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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\u30b3\u30e1\u30f3\u30c8<\/strong><\/p>\n

REDUCE-IT\u8a66\u9a13\uff08Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u6291\u5236\u8a66\u9a13\uff09(1)\u3067\u306f\u3001\u9ad8\u7528\u91cf\u306eEPA\u304c\u6709\u610f\u306a\u81e8\u5e8a\u7684\u6709\u7528\u6027\u3092\u793a\u3057\u305f\u304c\u3001STRENGTH\u8a66\u9a13\u3067\u5f97\u3089\u308c\u305f\u3053\u308c\u3089\u306e\u6b8b\u5ff5\u306a\u6240\u898b\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u4e88\u9632\u306b\u304a\u3051\u308b\u30aa\u30e1\u30ac-3\u8102\u80aa\u9178\u306e\u4f7f\u7528\u306b\u3064\u3044\u3066\u591a\u304f\u306e\u7591\u554f\u3092\u6295\u3052\u304b\u3051\u3066\u3044\u308b\u3002\u4eca\u6708\u306eEditorial\u306f\u3001\u3053\u308c\u3089\u306e\u7591\u554f\u306e\u591a\u304f\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3044\u308b\uff1a\u3053\u308c\u3089\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u5f97\u3089\u308c\u305f\u77db\u76fe\u3057\u305f\u6240\u898b\u306f\u3001EPA\u306e\u6295\u4e0e\u91cf\uff08\u304a\u3088\u3073\u6cbb\u7642\u4e2d\u306e\u8840\u4e2d\u6fc3\u5ea6\uff09\u3001\u60a3\u8005\u96c6\u56e3\u3001\u3042\u308b\u3044\u306f\u6bd4\u8f03\u5bfe\u7167\u85ac\u306e\u52b9\u679c\uff08\u3042\u308b\u3044\u306f\u305d\u306e\u6b20\u5982\uff09\u306e\u9055\u3044\u306b\u3088\u3063\u3066\u8aac\u660e\u3067\u304d\u308b\u306e\u3060\u308d\u3046\u304b\uff1f <\/p>\n

STRENGTH\u306b\u304a\u3051\u308b\u6709\u52b9\u6027\u306e\u6b20\u5982\u3060\u3051\u3067\u306a\u304f\u3001\u5b89\u5168\u6027\u306b\u304a\u3044\u3066\u3082\u91cd\u8981\u306a\u61f8\u5ff5\u304c\u3042\u3063\u305f\u3002REDUCE-IT\u3067\u3082\u3001\u5fc3\u623f\u7d30\u52d5\u306e\u767a\u751f\u7387\uff085.3\uff05\u5bfe\u6bd4\u8f03\u7fa43.9\uff05\uff09\u3001\u5fc3\u623f\u7d30\u52d5\u307e\u305f\u306f\u5fc3\u623f\u7c97\u52d5\u306b\u3088\u308b\u5165\u9662\uff083.1\uff05\u5bfe2.1\uff05\u3001p=0.004\uff09\u3068\u3082\u306b\u3001\u540c\u69d8\u306e\u6709\u5bb3\u30b7\u30b0\u30ca\u30eb\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\uff081\uff09\u3002\u3055\u3089\u306b\u3001\u6700\u8fd1\u5fc3\u7b4b\u6897\u585e\u3092\u767a\u75c7\u3057\u305f\u9ad8\u9f62\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305fOMEMI\u8a66\u9a13\uff08OMega-3 fatty acids in Elderly patients with Myocardial Infarction\uff09\u3067\u306f\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\uff081.8g\/\u65e5\uff09\u306f\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u4e88\u9632\u306b\u6709\u76ca\u3067\u306f\u306a\u304f\u3001\u5fc3\u623f\u7d30\u52d5\u306e\u767a\u751f\u7387\u3082\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\uff087.2\uff05\u5bfe\u6bd4\u8f03\u7fa4\u30674.0\uff05\u3001p=0.06\uff09(2)\u3002\u660e\u3089\u304b\u306b\u3001\u30aa\u30e1\u30ac-3\u8102\u80aa\u9178\u3067\u89b3\u5bdf\u3055\u308c\u305f\u5fc3\u623f\u7d30\u52d5\u306b\u5bfe\u3059\u308b\u3053\u306e\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u7279\u306b\u3001\u5fc3\u623f\u7d30\u52d5\u306e\u6709\u75c5\u7387\u306f\u3001\u9ad8\u9f62\u3067\u3042\u308b\u305f\u3081\u306b\u4e88\u60f3\u3055\u308c\u308b\u60a3\u8005\u96c6\u56e3\u306e\u4e2d\u3067\u9ad8\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u304b\u3089\u3067\u3042\u308b(3)\u3002
<\/strong><\/p>\n<\/div>\n\n\n\n\n
\u53c2\u8003\u6587\u732e<\/strong><\/td>\n\n

1.Bhatt DL, Steg PG, Miller M, et al; REDUCE-IT Investigators.\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u3002N Engl J Med 2019;380:11-22. <\/p>\n

2.Kalstad AA, Myhre PL, Laake K, et al, on behalf of the OMEMI Investigators.\u5fc3\u7b4b\u6897\u585e\u5f8c\u306e\u9ad8\u9f62\u60a3\u8005\u306b\u304a\u3051\u308bn-3\u7cfb\u8102\u80aa\u9178\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u52b9\u679c\uff1a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3002Circulation 2020; doi\/10.1161\/CIRCULATIONAHA.120.052209. <\/p>\n

3.\u5fc3\u623f\u7d30\u52d5\u306e\u6709\u75c5\u7387\u3001\u767a\u75c7\u7387\u3001\u751f\u6daf\u30ea\u30b9\u30af\uff1a\u30ed\u30c3\u30c6\u30eb\u30c0\u30e0\u7814\u7a76\u3002Eur Heart J 2006;27:949-53. <\/p>\n<\/td>\n<\/tr>\n

\u30ad\u30fc\u30ef\u30fc\u30c9<\/strong><\/td>\nSTRENGTH; REDUCE-IT; \u30aa\u30e1\u30ac3\u8102\u80aa\u9178; \u5fc3\u623f\u7d30\u52d5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"

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