{"id":254419,"date":"2025-01-25T13:42:03","date_gmt":"2025-01-25T12:42:03","guid":{"rendered":"https:\/\/r3i.org\/%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-%e6%ae%8b%e5%ad%98%e3%83%aa%e3%83%9d%e8%9b%8b%e7%99%bd%e3%81%af%e5%a4%a7%e5%8b%95%e8%84%88%e5%bc%81%e7%8b%ad%e7%aa%84%e7%97%87%e3%81%ae%e3%83%aa\/"},"modified":"2025-02-16T22:42:47","modified_gmt":"2025-02-16T21:42:47","slug":"%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-%e6%ae%8b%e5%ad%98%e3%83%aa%e3%83%9d%e8%9b%8b%e7%99%bd%e3%81%af%e5%a4%a7%e5%8b%95%e8%84%88%e5%bc%81%e7%8b%ad%e7%aa%84%e7%97%87%e3%81%ae%e3%83%aa","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e3%83%a9%e3%83%b3%e3%83%89%e3%83%9e%e3%83%bc%e3%82%af-%e6%ae%8b%e5%ad%98%e3%83%aa%e3%83%9d%e8%9b%8b%e7%99%bd%e3%81%af%e5%a4%a7%e5%8b%95%e8%84%88%e5%bc%81%e7%8b%ad%e7%aa%84%e7%97%87%e3%81%ae%e3%83%aa\/","title":{"rendered":"\u30e9\u30f3\u30c9\u30de\u30fc\u30af-\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;1px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_2_text_color=&#8221;gcid-primary-color&#8221; header_5_text_color=&#8221;gcid-secondary-color&#8221; text_orientation=&#8221;center&#8221; width=&#8221;99%&#8221; custom_margin=&#8221;|-147px||||&#8221; custom_padding=&#8221;|0px||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}&#8221; sticky_enabled=&#8221;0&#8243;]<h2><span>\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b<\/span><\/h2>\n<h5><span>2 2020\u5e746\u6708<\/span><\/h5>\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\">\n<div class=\"summary\"><span>Copenhagen General Population Study\u306e\u30c7\u30fc\u30bf\u306b\u3088\u308b\u3068\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08TG\uff09\u3068\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5024\u304c\u9ad8\u304f\u306a\u308b\u3068\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u3002<\/span><\/div>\n<div class=\"authors\"><span>Kaltoft M, Langsted A, Nordestgaard BG.\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u30b3\u30da\u30f3\u30cf\u30fc\u30b2\u30f3\u4e00\u822c\u4eba\u53e3\u7814\u7a76\u306b\u304a\u3051\u308b\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u3002Eur Heart J 2020. doi: 10.1093\/eurheartj\/ehaa172   <\/span><\/div>\n<div class=\"authors\"><span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"authors\">\n<p><strong>\u7814\u7a76\u6982\u8981<\/strong><\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\" width=\"17%\"><strong>\u76ee\u7684<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\" width=\"83%\">\u8840\u6f3f\u4e2dTG\u304a\u3088\u3073\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u9ad8\u5024\u304c\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u4e0a\u6607\u3068\u89b3\u5bdf\u4e0a\u304a\u3088\u3073\u907a\u4f1d\u5b66\u7684\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u30c7\u30b6\u30a4\u30f3<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u30e1\u30f3\u30c7\u30eb\u7121\u4f5c\u70ba\u5316\u8a66\u9a13<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td valign=\"top\" bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u96c6\u56e3<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u672c\u7814\u7a76\u3067\u306f\u3001Copenhagen General Population Study\u306e108,559\u4eba\u306e\u30c7\u30fc\u30bf\u3092\u7528\u3044\u305f\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u6210\u679c\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u767a\u75c7\u3067\u3042\u3063\u305f\u3002\u65e2\u77e5\u306e\u5148\u5929\u6027\u5927\u52d5\u8108\u5f01\u5947\u5f62\u3092\u6709\u3059\u308b\u60a3\u8005\u306f\u9664\u5916\u3055\u308c\u305f\u3002 <\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u65b9\u6cd5\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u8840\u6f3f\u4e2dTG\u3001\u6b8b\u4f59\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304b\u3089\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d[LDL] \u3001\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u9664\u3044\u305f\u3082\u306e\uff09\u304c\u6e2c\u5b9a\u3055\u308c\u305f\u3002\u8840\u6f3f\u4e2dTG\u304a\u3088\u3073\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5897\u52a0\u307e\u305f\u306f\u6e1b\u5c11\u3092\u5f15\u304d\u8d77\u3053\u3059ANGPTL3\u3001ANGPTL4\u3001APOA5\u3001APOC3\u3001LPL\u304a\u3088\u3073TRIB1\u907a\u4f1d\u5b50\u306e16\u306e\u5909\u7570\u4f53\u3092\u7528\u3044\u3066\u5bfe\u7acb\u907a\u4f1d\u5b50\u30b9\u30b3\u30a2\u3092\u4f5c\u6210\u3057\u305f\u3002TG\u304a\u3088\u3073\u30ec\u30e0\u30ca\u30f3\u30c8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u3068\u306e\u89b3\u5bdf\u7684\u95a2\u9023\u306f\u3001\u5e74\u9f62\u304a\u3088\u3073\u6027\u5225\u3067\u8abf\u6574\u3057\u305fCox\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u56de\u5e30\u3001\u307e\u305f\u306f\u5e74\u9f62\u3001\u6027\u5225\u3001\u55ab\u7159\u72b6\u6cc1\u3001\u55ab\u7159\u7bb1\u5e74\u6570\u3001\u53ce\u7e2e\u671f\u8840\u5727\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u3001\u6559\u80b2\u5e74\u6570\u3067\u591a\u56e0\u5b50\u8abf\u6574\u3057\u305fCox\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u56de\u5e30\u3092\u7528\u3044\u3066\u7b97\u51fa\u3057\u305f\u3002TG\u306f1mmol\/L\u5909\u5316\u3054\u3068\u306b6\u7fa4\u306b\u5206\u985e\u3055\u308c\u305f\uff1a&lt;1.0 mmol\/L\uff08&lt;89 mg\/dL\uff09\u30011.0-1.9 mmol\/L\uff0889-176 mg\/dL\uff09\u30012.0-2.9 mmol\/L\uff08177-265 mg\/dL\uff09\u30013.0-3.9 mmol\/L\uff08266-353 mg\/dL\uff09\u30014.0-4.9 mmol\/L\uff08354-442 mg\/dL\uff09\u30015.0 mmol\/L\u4ee5\u4e0a\uff08443 mg\/dL\uff09\u3002\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f0.5mmol\/L\u5909\u5316\u30675\u7fa4\u306b\u5206\u985e\u3055\u308c\u305f\uff1a&lt;0.5mmol\/L\uff08&lt;\u30fb19mg\/dL\uff09\u30010.5-0.9mmol\/L\uff0819-38mg\/dL\uff09\u30011.0-1.4mmol\/L\uff0839-57mg\/dL\uff09\u30011.5-1.9mmol\/L\uff0858-76mg\/dL\uff09\u30012.0mmol\/L\u4ee5\u4e0a\uff0877mg\/dL\u4ee5\u4e0a\uff09\u3002\u907a\u4f1d\u7684\u5bfe\u7acb\u907a\u4f1d\u5b50\u30b9\u30b3\u30a2\u3068\u306e\u95a2\u9023\u306f\u3001\u5e74\u9f62\u304a\u3088\u3073\u6027\u5225\u3092\u5171\u5909\u91cf\u3068\u3057\u305f\u30ed\u30b8\u30b9\u30c6\u30a3\u30c3\u30af\u56de\u5e30\u306b\u3088\u308a\u7b97\u51fa\u3057\u305f\u3002\u56e0\u679c\u95a2\u4fc2\u3092\u5b9a\u91cf\u5316\u3059\u308b\u305f\u3081\u306b\u3001\u5bfe\u7acb\u907a\u4f1d\u5b50\u30b9\u30b3\u30a2\u3092\u9053\u5177\u5909\u6570\u3068\u3057\u305f\u9053\u5177\u5909\u6570\u89e3\u6790\u304c\u884c\u308f\u308c\u305f\u3002        <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u7d50\u679c<\/strong><\/p>\n<table width=\"640\">\n<tbody>\n<tr>\n<td width=\"513\">\n<p>\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306f\u3001\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u50248.7\u5e74\uff08\u7bc4\u56f20\u301c14\u5e74\uff09\u306e\u9593\u306b1593\u4eba\u306b\u767a\u751f\u3057\u305f\u3002<\/p>\n<p><em>\u89b3\u5bdf\u30ea\u30b9\u30af<\/em><\/p>\n<p>TG\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u5897\u52a0\u306f\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u305f<strong>\uff08\u88681<\/strong>\uff09\u3002TG&lt;2.0 mmol\/L (&lt;177 mg\/dL)\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u3001TG 2.0-4.9 mmol\/L (177- 442 mg\/dL)\u306e\u4eba\u3067\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u306f31\uff05\u5897\u52a0\u3057\u3001TG 5 mmol\/L (443mg\/dL)\u4ee5\u4e0a\u306e\u4eba\u3067\u306f64\uff05\u5897\u52a0\u3057\u305f\u3002\u30ea\u30b9\u30af\u306f\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u9ad8\u304f\u306a\u308b\u306b\u3064\u308c\u3066\u540c\u69d8\u306b\u5897\u52a0\u3057\u305f\u3002  <\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u88681. \u8840\u6f3f\u4e2d\u306e\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u30ea\u30b9\u30af\u3068\u306e\u89b3\u5bdf\u7684\u95a2\u9023\u6027<\/strong><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"study-table\">\n<tbody>\n<tr>\n<td width=\"137\">\n<p>\u53ef\u5909<\/p>\n<\/td>\n<td width=\"161\">\n<p>mmol\/L (mg\/dL)<\/p>\n<\/td>\n<td width=\"200\">\n<p>\u30cf\u30b6\u30fc\u30c9\u6bd4\uff0895\uff05CI\uff09<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>TG<\/p>\n<\/td>\n<td width=\"161\">\n<p>&lt;1 (&lt;89)<\/p>\n<\/td>\n<td width=\"200\">\n<p>\u53c2\u8003<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>1.0-1.9 (89-176)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.02 (0.87 &#8211; 1.19)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>2.0-2.9 (177-265)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.22 (1.02 -1.46)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>3.0-3.9 (266-353)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.40 (1.11 &#8211; 1.77)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>4.0-4.9 (354-442)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.29 (0.88 &#8211; 1.90)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>\u22655 (\u2265443)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.52 (1.02 &#8211; 2.27)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"200\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb<\/p>\n<\/td>\n<td width=\"161\">\n<p>&lt;0.5 (&lt;19)<\/p>\n<\/td>\n<td width=\"200\">\n<p>\u53c2\u8003<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>0.5-0.9 (19-38)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.06 (0.92 &#8211; 1.22)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>1.0-1.4 (39-57)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.31 (1.11 &#8211; 1.56)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>1.5-1.9 (58-76)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.43 (1.12 &#8211; 1.84)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>&nbsp;<\/p>\n<\/td>\n<td width=\"161\">\n<p>\u22652.0 (\u226577)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.48 (0.91 &#8211; 2.43)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span>TG\u304c1mmol\/L\uff0889mg\/dL\uff09\u5897\u52a0\u3059\u308b\u3054\u3068\u306b\u3001\u307e\u305f\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c0.39mmol\/L\uff0815mg\/dL\uff09\u5897\u52a0\u3059\u308b\u3054\u3068\u306b\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u89b3\u5bdf\u4e0a\u306e\u30ea\u30b9\u30af\u306f1.1\u500d\u5897\u52a0\u3057\u305f\uff08\u30cf\u30b6\u30fc\u30c9\u6bd4\u306f\u305d\u308c\u305e\u308c1.09\u300195\uff05\u4fe1\u983c\u533a\u95931.05-1.14\u30011.10\u300195\uff05\u4fe1\u983c\u533a\u95931.05-1.15\uff09\u3002<\/span><\/p>\n<table width=\"640\">\n<tbody>\n<tr>\n<td width=\"513\">\n<p><em>\u907a\u4f1d\u7684\u30ea\u30b9\u30af<\/em><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"513\">\n<p>\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u306f\u5bfe\u7acb\u907a\u4f1d\u5b50\u30b9\u30b3\u30a2\u304c\u9ad8\u304f\u306a\u308b\u306b\u3064\u308c\u3066\u5897\u52a0\u3057\u305f<strong>\uff08\u88682\uff09<\/strong>\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u88682.\u8840\u6f3f\u4e2d\u306e\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u30ea\u30b9\u30af\u3068\u306e\u907a\u4f1d\u7684\u95a2\u9023 <\/strong><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"authors\">\n<table class=\"study-table\">\n<tbody>\n<tr>\n<td width=\"137\">\n<p>\u52a0\u91cd\u5bfe\u7acb\u907a\u4f1d\u5b50\u30b9\u30b3\u30a2\u7fa4<\/p>\n<\/td>\n<td width=\"161\">\n<p>TG\u5897\u52a0\u7387\uff08\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5897\u52a0\u7387\uff09<\/p>\n<\/td>\n<td width=\"200\">\n<p>\u30cf\u30b6\u30fc\u30c9\u6bd4\uff0895\uff05CI\uff09<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>1<\/p>\n<\/td>\n<td width=\"161\">\n<p>\u53c2\u8003<\/p>\n<\/td>\n<td width=\"200\">\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>2<\/p>\n<\/td>\n<td width=\"161\">\n<p>20 (18)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.11 (1.02 &#8211; 1.21)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>3<\/p>\n<\/td>\n<td width=\"161\">\n<p>35 (31)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.21 (1.13 &#8211; 1.31)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"137\">\n<p>4<\/p>\n<\/td>\n<td width=\"161\">\n<p>63 (55)<\/p>\n<\/td>\n<td width=\"200\">\n<p>1.31 (1.06 &#8211; 1.60)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"authors\">\n<div>\n<p><strong><span>TG\u304c1mmol\/L\uff0889mg\/dL\uff09\u5897\u52a0\u3059\u308b\u3054\u3068\u306b\u3001\u307e\u305f\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c0.39mmol\/L\uff0815mg\/dL\uff09\u5897\u52a0\u3059\u308b\u3054\u3068\u306b\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u304c1.6\u500d\u5897\u52a0\u3057\u305f\uff08\u30ea\u30b9\u30af\u6bd4\u306f\u305d\u308c\u305e\u308c1.62\u300195\uff05\u4fe1\u983c\u533a\u95931.15-2.29\u30011.62\u300195\uff05\u4fe1\u983c\u533a\u95931.15-2.29\uff09\u3002<\/span><\/strong><\/p>\n<p><strong><\/strong><\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7d50\u8ad6<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u9ad8TG\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001\u89b3\u5bdf\u7684\u306b\u3082\u907a\u4f1d\u7684\u306b\u3082\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u4e0a\u6607\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div>\n<p><strong>\u30b3\u30e1\u30f3\u30c8<\/strong><\/p>\n<p>\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306f\u3001\u9ad8\u9f62\u5316\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u307e\u3059\u307e\u3059\u4e00\u822c\u7684\u306b\u306a\u3063\u3066\u304a\u308a\u300180\u6b73\u306e\u9ad8\u9f62\u8005\u306e\u6700\u592710\uff05\u304c\u7f79\u60a3\u3057\u3066\u3044\u308b\u3002\u3044\u3063\u305f\u3093\u75c7\u72b6\u304c\u51fa\u308c\u3070\u3001\u6cbb\u7642\u306e\u9078\u629e\u80a2\u306f\u9650\u3089\u308c\u3001\u4e88\u5f8c\u306f\u4e0d\u826f\u3067\u3042\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u5371\u967a\u56e0\u5b50\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u306f\u3001\u7ba1\u7406\u6226\u7565\u3092\u6539\u5584\u3059\u308b\u4e0a\u3067\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002\u3053\u308c\u3089\u306e\u5371\u967a\u56e0\u5b50\u306f\u4ed6\u306e\u8840\u7ba1\u75be\u60a3\u306b\u95a2\u4e0e\u3059\u308b\u3082\u306e\u3068\u985e\u4f3c\u3057\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u6cbb\u7642\u6cd5\u306e\u7121\u4f5c\u70ba\u5316\u8a66\u9a13\u3067\u306f\u3001\u75be\u60a3\u306e\u9032\u884c\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u306f\u307b\u3068\u3093\u3069\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f(2-4)\u3002   <\/p>\n<p>\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u306b\u304a\u3051\u308bTG\u30ea\u30c3\u30c1\u306a\u6b8b\u4f59\u30ea\u30dd\u86cb\u767d\u306e\u539f\u56e0\u7684\u5f79\u5272\u304c\u8a8d\u8b58\u3055\u308c\u308b\u306b\u3064\u308c\uff085,6\uff09\u3001\u3053\u308c\u3089\u306e\u30ea\u30dd\u86cb\u767d\u304c\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u308b\u3002\u3053\u306e\u7591\u554f\u306f\u4eca\u56de\u306e\u7814\u7a76\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u305f\u3002\u7814\u7a76\u8005\u3089\u306fCopenhagen General Population Study\u306e\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u6cd5\u3092\u7528\u3044\u3001\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u3068\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u3068\u306e\u95a2\u9023\u3092\u691c\u8a3c\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u8840\u6f3f\u4e2d\u306eTG\u304a\u3088\u3073\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u3044\u307b\u3069\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u89b3\u5bdf\u7684\u306b\u3082\u907a\u4f1d\u7684\u306b\u3082\u793a\u3055\u308c\u3001\u3053\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u9032\u5c55\u306bTG\u3092\u591a\u304f\u542b\u3080\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u306e\u4e0a\u6607\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u305f\u3002\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75c5(7)\u3067\u793a\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001\u708e\u75c7\u306e\u4fc3\u9032\u3092\u542b\u3080\u3068\u601d\u308f\u308c\u308b\u304c\u3001\u3053\u306e\u7814\u7a76\u3067\u306f\u305d\u306e\u57fa\u790e\u306b\u3042\u308b\u6a5f\u5e8f\u306b\u3064\u3044\u3066\u306e\u6d1e\u5bdf\u306f\u5f97\u3089\u308c\u3066\u3044\u306a\u3044\u3002    <\/p>\n<\/div>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr>\n<td valign=\"top\" bgcolor=\"#E9E9E9\" width=\"13%\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/td>\n<td valign=\"top\" bgcolor=\"#FFFFFF\" width=\"87%\">\n<p>1.Joseph J, Naqvi SY, Giri J, Goldberg S. Aortic stenosis: Pathophysiology, diagnosis, and therapy.Am J Med 2017;130:253-63. <\/p>\n<p>2.\u77f3\u7070\u6c88\u7740\u6027\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306b\u304a\u3051\u308b\u96c6\u4e2d\u7684\u8102\u8cea\u4f4e\u4e0b\u7642\u6cd5\u306e\u7121\u4f5c\u70ba\u8a66\u9a13\u3002N Engl J Med 2005;352:2389-97.  <\/p>\n<p>3.\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306b\u304a\u3051\u308b\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u3068\u30a8\u30bc\u30c1\u30df\u30d6\u306b\u3088\u308b\u96c6\u4e2d\u7684\u8102\u8cea\u4f4e\u4e0b\u7642\u6cd5\u3002N Engl J Med 2008;359:1343-56.  <\/p>\n<p>4.Chan KL, Teo K, Dumesnil JG, et al. <\/p>\n<p>\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u9032\u884c\u306b\u5bfe\u3059\u308b\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f3\u306b\u3088\u308b\u8102\u8cea\u4f4e\u4e0b\u306e\u52b9\u679c\uff1a\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u9032\u884c\u89b3\u5bdf\uff1a\u30ed\u30b9\u30d0\u30b9\u30bf\u30c1\u30f3\u306e\u52b9\u679c\u6e2c\u5b9a\uff08ASTRONOMER\uff09\u8a66\u9a13\u306e\u7d50\u679c\u3002Circulation 2010;121:306-14. <\/p>\n<p>5.Nordestgaard BG, Varbo A. \u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3068\u5fc3\u8840\u7ba1\u75be\u60a3\u3002Lancet 2014;384:626-35. <\/p>\n<p>6.Laufs U, Parhofer KG, Ginsberg HN, Hegele RA.\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u30ec\u30d3\u30e5\u30fc\u3002Eur Heart J 2020;41:99-109c.  <\/p>\n<p>7.Varbo A, Benn M, Tybj\u00e6rg-Hansen A, Nordestgaard BG.\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607\u306f\u3001\u4f4e\u60aa\u6027\u5ea6\u306e\u708e\u75c7\u3068\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u4e21\u65b9\u3092\u5f15\u304d\u8d77\u3053\u3059\u304c\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607\u306f\u3001\u708e\u75c7\u3092\u4f34\u308f\u305a\u306b\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002Circulation 2013;128:1298-309.  <\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b 2 2020\u5e746\u6708 Copenhagen General Po [&hellip;]<\/p>\n","protected":false},"author":258497325,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_crdt_document":"","jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-254419","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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