{"id":254395,"date":"2025-01-21T13:29:29","date_gmt":"2025-01-21T12:29:29","guid":{"rendered":"https:\/\/r3i.org\/%e7%94%bb%e6%9c%9f%e7%9a%84-%e6%ae%8b%e7%95%99%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%a8%e5%bf%83%e8%a1%80%e7%ae%a1%e8%bb%a2%e5%b8%b0%e3%82%92%e9%96%a2%e9%80%a3\/"},"modified":"2025-02-16T22:36:44","modified_gmt":"2025-02-16T21:36:44","slug":"%e7%94%bb%e6%9c%9f%e7%9a%84-%e6%ae%8b%e7%95%99%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%a8%e5%bf%83%e8%a1%80%e7%ae%a1%e8%bb%a2%e5%b8%b0%e3%82%92%e9%96%a2%e9%80%a3","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e7%94%bb%e6%9c%9f%e7%9a%84-%e6%ae%8b%e7%95%99%e3%82%b3%e3%83%ac%e3%82%b9%e3%83%86%e3%83%ad%e3%83%bc%e3%83%ab%e3%81%a8%e5%bf%83%e8%a1%80%e7%ae%a1%e8%bb%a2%e5%b8%b0%e3%82%92%e9%96%a2%e9%80%a3\/","title":{"rendered":"\u753b\u671f\u7684 – \u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5fc3\u8840\u7ba1\u8ee2\u5e30\u3092\u95a2\u9023\u3065\u3051\u308b\u3088\u308a\u591a\u304f\u306e\u8a3c\u62e0"},"content":{"rendered":"\n[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”1px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_2_text_color=”gcid-primary-color” header_5_text_color=”gcid-secondary-color” text_orientation=”center” width=”99%” custom_margin=”|-147px||||” custom_padding=”|0px||||” hover_enabled=”0″ global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}” sticky_enabled=”0″]

\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5fc3\u8840\u7ba1\u8ee2\u5e30\u3092\u95a2\u9023\u4ed8\u3051\u308b\u3088\u308a\u591a\u304f\u306e\u8a3c\u62e0<\/span><\/h2>\n
2023\u5e749\u670826\u65e5<\/span><\/h5>\n
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\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u7cfb\u306e\u8ee2\u5e30\u306b\u5bfe\u3059\u308b\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u72ec\u7acb\u56e0\u679c\u95a2\u4fc2\uff1a\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u7814\u7a76\u3002Arterioscler Thromb Vasc Biol 2023; doi: 10.1161\/ATVBAHA.123.319297. <\/em><\/p>\n

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\u7814\u7a76\u6982\u8981<\/strong><\/td>\n<\/tr>\n
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\u7814\u7a76\u96c6\u56e3\uff1a<\/strong><\/td>\nCARDIoGRAMplusC4D\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0\uff08Coronary Artery Disease Genome-Wide Replication and Meta-Analysis Plus the Coronary Artery Disease Genetics\uff09\u3001Metastroke\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0\u3001GLGC\uff08Global Lipids Genetics Consortium\uff09\u306b\u304a\u3051\u308b958 434\u4eba\u306e\u88ab\u9a13\u8005\u306e\u8907\u5408\u30b5\u30f3\u30d7\u30eb\u306e\u30c7\u30fc\u30bf\u3002<\/td>\n<\/tr>\n
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\u53c2\u8003\u6587\u732e<\/strong><\/td>\n1.Nordestgaard BG\u3002Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology.Circ Res 2016;118:547-63.
2.Varbo A, Benn M, Tybj\u00e6rg-Hansen A, J\u00f8rgensen AB, Frikke-Schmidt R, Nordestgaard BG.\u865a\u8840\u6027\u5fc3\u75be\u60a3\u306e\u539f\u56e0\u5371\u967a\u56e0\u5b50\u3068\u3057\u3066\u306e\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3002J Am Coll Cardiol 2013; 61:427-36.
3.Jepsen AM, Langsted A, Varbo A, Bang LE, Kamstrup PR, Nordestgaard BG.5414\u4eba\u306e\u865a\u8840\u6027\u5fc3\u75be\u60a3\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5897\u52a0\u304c\u5168\u6b7b\u4ea1\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u306e\u4e00\u90e8\u3092\u8aac\u660e\u3057\u3066\u3044\u308b\u3002Clin Chem 2016; 62:593-604.
4.Ginsberg HN, Packard CJ, Chapman MJ, et al. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.Eur Heart J 2021; 42:4791-806\u3002
5.\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75c5\u306e\u72ec\u7acb\u3057\u305f\u4e88\u6e2c\u56e0\u5b50\u3068\u3057\u3066\u306e\u8840\u6e05\u4f4e\u5bc6\u5ea6\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u30ea\u30c3\u30c1\u30ec\u30e0\u30ca\u30f3\u30c8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u6e2c\u5b9a\uff1a\u53ef\u80fd\u6027\u3068\u9650\u754c\u3002
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8.Nicholls SJ, Lincoff AM, Garcia M, et al. \u9ad8\u7528\u91cf\u30aa\u30e1\u30ac3\u8102\u80aa\u9178vs\u30b3\u30fc\u30f3\u6cb9\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u52b9\u679c\uff1aSTRENGTH\u7121\u4f5c\u70ba\u5316\u81e8\u5e8a\u8a66\u9a13\u3002JAMA 2020; 324: 2268-80. <\/td>\n<\/tr>\n
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