{"id":254370,"date":"2025-01-21T23:09:26","date_gmt":"2025-01-21T22:09:26","guid":{"rendered":"https:\/\/r3i.org\/%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-%e7%b3%96%e5%b0%bf%e7%97%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%a8%e6%ad%bb\/"},"modified":"2025-02-16T22:31:25","modified_gmt":"2025-02-16T21:31:25","slug":"%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-%e7%b3%96%e5%b0%bf%e7%97%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%a8%e6%ad%bb","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-%e7%b3%96%e5%b0%bf%e7%97%85%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%a8%e6%ad%bb\/","title":{"rendered":"\u30d5\u30a9\u30fc\u30ab\u30b9 – \u7cd6\u5c3f\u75c5\u306b\u304a\u3051\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3068\u6b7b\u4ea1\u30ea\u30b9\u30af"},"content":{"rendered":"\n[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”1px|||||” global_colors_info=”{}”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_2_text_color=”gcid-primary-color” header_5_text_color=”gcid-secondary-color” text_orientation=”center” width=”99%” custom_margin=”|-147px||||” custom_padding=”|0px||||” hover_enabled=”0″ global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}” sticky_enabled=”0″]

\u30d5\u30a9\u30fc\u30ab\u30b9 –\u7cd6\u5c3f\u75c5\u306b\u304a\u3051\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3068\u6b7b\u4ea1\u30ea\u30b9\u30af<\/span><\/h2>\n
2022 \u5e74 2 \u6708 21 \u65e5<\/span><\/h5>\n

NHANES\uff08National Health and Nutrition Examination Surveys\uff09\u306b\u3088\u308b\u3053\u306e\u5831\u544a\u3067\u306f\u3001\u7a7a\u8179\u6642\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u5024\u304c\u9ad8\u3044\u307b\u3069\u7cd6\u5c3f\u75c5\u306b\u95a2\u9023\u3057\u305f\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/em><\/p>\n

Wadstr\u00f6m BN, Wang Y. \u9ad8\u3044\u7a7a\u8179\u6642\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306f\u3001\u7c73\u56fd\u6210\u4eba\u306b\u304a\u3051\u308b\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u30ea\u30b9\u30af\u306e\u4e0a\u6607\u3092\u4e88\u6e2c\u3059\u308b\u3002Lipids in Health and Disease 2021;20:181. <\/em><\/p>\n

\u7814\u7a76\u6982\u8981<\/b><\/p>\n\n\n\n\n\n\n\n
\u76ee\u7684<\/strong><\/td>\n\u7a7a\u8179\u6642\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08TG\uff09\u3068\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u7387\u3068\u306e\u95a2\u9023\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3002<\/td>\n<\/tr>\n
\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a<\/strong><\/td>\nNHANES\uff081988-2014\u5e74\uff09\u30c7\u30fc\u30bf\u306e\u30b3\u30db\u30fc\u30c8\u89e3\u6790\u3002<\/td>\n<\/tr>\n
\u7814\u7a76\u5bfe\u8c61\u8005\uff1a<\/strong><\/td>\n27,067\u4eba\uff08\u7cd6\u5c3f\u75c5\u306a\u305722,909\u4eba\u3001\u7cd6\u5c3f\u75c5\u3042\u308a3673\u4eba\uff09\u3001\u5e73\u5747\u5e74\u9f6249\u6b73\u3001NHANES III\uff081988-1999\u5e74\uff09\u304a\u3088\u3073NHANES IV\uff081999-2014\u5e74\uff09\u306b\u542b\u307e\u308c\u308b\u7a7a\u8179\u6642TG\u30c7\u30fc\u30bf\u3002<\/td>\n<\/tr>\n
\u4e00\u6b21\u5909\u6570\uff1a<\/strong><\/td>\n\u7cd6\u5c3f\u75c5\u95a2\u9023\u6b7b\u4ea1\u3001\u3059\u306a\u308f\u3061\u7cd6\u5c3f\u75c5\u304c\u6b7b\u4ea1\u306e\u57fa\u790e\u539f\u56e0\u3068\u3057\u3066\u8a18\u8f09\u3055\u308c\u3066\u3044\u305f\u3002\u7cd6\u5c3f\u75c5\u306f\u3001\u7a7a\u8179\u6642\u8840\u7cd6\u5024126mg\/dL\u4ee5\u4e0a\u3001HbA1c 6.5\uff05\u4ee5\u4e0a\u3001\u8840\u7cd6\u964d\u4e0b\u85ac\u670d\u7528\u4e2d\u3001\u307e\u305f\u306f\u81ea\u5df1\u7533\u544a\u306b\u3088\u308b\u8a3a\u65ad\u3068\u5b9a\u7fa9\u3055\u308c\u305f\u3002 <\/td>\n<\/tr>\n
\u65b9\u6cd5\uff1a<\/strong><\/td>\nCox\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3001\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u306b\u5bfe\u3059\u308bTG\u306e\u30cf\u30b6\u30fc\u30c9\u6bd4\uff08HR\uff09\u306895\uff05\u4fe1\u983c\u533a\u9593\uff08CI\uff09\u3092\u7b97\u51fa\u3057\u305f\u3002\u30e2\u30c7\u30eb\u306f\u5e74\u9f62\u3001\u6027\u3001\u6c11\u65cf\u3001\u80a5\u6e80\u3001\u8ca7\u56f0\u6240\u5f97\u6bd4\u7387\u3001\u6559\u80b2\u3001\u8eab\u4f53\u6d3b\u52d5\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u3001\u55ab\u7159\u72b6\u6cc1\u3001\u8abf\u67fb\u671f\u9593\u3001\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u3001\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u7cd6\u5c3f\u75c5\u306e\u5bb6\u65cf\u6b74\u3067\u8abf\u6574\u3057\u305f\u3002 <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u7d50\u679c<\/strong><\/p>\n

319,758\u4eba\u5e74\uff08\u5e73\u5747\u8ffd\u8de1\u671f\u959312.0\u5e74\uff09\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u3001582\u4eba\u304c\u7cd6\u5c3f\u75c5\u306b\u3088\u308a\u6b7b\u4ea1\u3057\u305f\u3002TG\u304c1\u81ea\u7136\u5bfe\u6570\u5358\u4f4d\u5897\u52a0\u3059\u308b\u3068\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f40\uff05\u9ad8\u304f\u306a\u308a\u3001\u3053\u306e\u95a2\u9023\u306f\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306e\u7cd6\u5c3f\u75c5\u306e\u6709\u7121\u306b\u304b\u304b\u308f\u3089\u305a\u660e\u3089\u304b\u3067\u3042\u3063\u305f\uff08\u88681\uff09\u3002TG\u5024\u304c\u6700\u3082\u4f4e\u3044\u4e94\u5206\u4f4d\u7fa4\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6700\u3082\u9ad8\u3044\u4e94\u5206\u4f4d\u7fa4\u306e\u4eba\u306f\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c85\uff05\u9ad8\u304b\u3063\u305f\uff08HR, 1.85; 95\uff05CI,1.25-2.73;p=0.002\uff09\u3002 <\/p>\n

\u88681. TG\u3068\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u7387\u3068\u306e\u95a2\u9023<\/strong><\/p>\n\n\n\n\n\n\n
\n

 <\/p>\n<\/td>\n

\n

N<\/p>\n<\/td>\n

\n

HR\uff0895\uff05\u4fe1\u983c\u533a\u9593\uff09<\/p>\n<\/td>\n

\n

p\u5024<\/p>\n<\/td>\n<\/tr>\n

\n

\u5168\u54e1<\/p>\n<\/td>\n

\n

26,582<\/p>\n<\/td>\n

\n

1.40 (1.20-1.64)<\/p>\n<\/td>\n

\n

<0.001<\/p>\n<\/td>\n<\/tr>\n

\n

\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u88ab\u9a13\u8005<\/p>\n<\/td>\n

\n

22,909<\/p>\n<\/td>\n

\n

1.45 (1.09-1.92)<\/p>\n<\/td>\n

\n

0.011<\/p>\n<\/td>\n<\/tr>\n

\n

\u7cd6\u5c3f\u75c5\u60a3\u8005<\/p>\n<\/td>\n

\n

3,673<\/p>\n<\/td>\n

\n

1.32 (1.09-1.58)<\/p>\n<\/td>\n

\n

0.004<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n
\u8457\u8005\u306e\u7d50\u8ad6<\/strong><\/td>\n\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u7a7a\u8179\u6642TG\u304c\u9ad8\u3044\u307b\u3069\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u306e\u305f\u3081\u306b\u3001\u81e8\u5e8a\u306b\u304a\u3044\u3066TG\u3092\u30eb\u30fc\u30c1\u30f3\u306b\u30e2\u30cb\u30bf\u30fc\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002 <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n

\u30b3\u30e1\u30f3\u30c8<\/strong><\/p>\n

2019\u5e74\u3001\u7cd6\u5c3f\u75c5\u306f\u4e16\u754c\u7b2c9\u4f4d\u306e\u6b7b\u56e0\u3068\u306a\u3063\u305f(1)\u3002\u904e\u53bb20\u5e74\u9593\u3067\u3001\u7cd6\u5c3f\u75c5\u306b\u95a2\u9023\u3059\u308b\u6b7b\u4ea1\u7387\u306f70\uff05\u4ee5\u4e0a\u5897\u52a0\u3057\u3001\u7537\u6027\u3067\u306f\u3055\u3089\u306b\u5897\u52a0\u3057\u3066\u3044\u308b\uff082\uff09\u3002\u3053\u306e\u3088\u3046\u306a\u75be\u75c5\u306e\u8ca0\u62c5\u306f\u3001\u4f4e\u30fb\u4e2d\u6240\u5f97\u56fd\u306b\u304a\u3044\u3066\u307e\u3059\u307e\u3059\u5927\u304d\u304f\u306a\u3063\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u5730\u57df\u306b\u304a\u3051\u308b\u7cd6\u5c3f\u75c5\u6709\u75c5\u7387\u306e\u4e0a\u6607\u50be\u5411\u3068\u4e00\u81f4\u3057\u3066\u3044\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u7cd6\u5c3f\u75c5\u306e\u4e88\u5f8c\u306b\u95a2\u9023\u3059\u308b\u4fee\u6b63\u53ef\u80fd\u306a\u56e0\u5b50\u3092\u540c\u5b9a\u3059\u308b\u3053\u3068\u306f\u3001\u7cd6\u5c3f\u75c5\u6b7b\u4ea1\u7387\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u306b\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002 <\/p>\n

\u4eca\u56de\u306eNHANES\u306e\u5831\u544a\u3067\u306f\u3001\u91cd\u8981\u306a\u60c5\u5831\u304c\u8ffd\u52a0\u3055\u308c\u305f\u3002Elevated TG, which are prevalent in individuals with type 2 diabetes, typically in combination with low plasma concentration of high-density lipoprotein cholesterol (atherogenic dyslipidemia) (3), are associated with an increased risk of diabetes mortality.\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u3001\u30b3\u30db\u30fc\u30c8\u306e\u898f\u6a21\u3001\u524d\u5411\u304d\u7814\u7a76\u306e\u30c7\u30b6\u30a4\u30f3\u3001\u89e3\u6790\u306b\u304a\u3051\u308b\u4ea4\u7d61\u56e0\u5b50\u306e\u8abf\u6574\u306b\u3088\u3063\u3066\u5f37\u5316\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u8457\u8005\u3089\u306f\u3001\u672c\u7814\u7a76\u304c\u3053\u306e\u95a2\u9023\u6027\u306e\u57fa\u790e\u306b\u3042\u308b\u6a5f\u5e8f\u306b\u95a2\u3059\u308b\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u3092\u8a8d\u3081\u3066\u3044\u308b\u3002\u3053\u308c\u3089\u3092\u7dcf\u5408\u3059\u308b\u3068\u3001\u3053\u306e\u89e3\u6790\u7d50\u679c\u306f\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u65e5\u5e38\u7ba1\u7406\u306b\u304a\u3051\u308bTG\u4e0a\u6607\u306e\u6cbb\u7642\u6a19\u7684\u5316\u3092\u3055\u3089\u306b\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u3002
<\/strong><\/p>\n<\/div>\n\n\n\n\n
\u53c2\u8003\u6587\u732e<\/strong><\/td>\n1.\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\uff08WHO\uff09\u3002\u7cd6\u5c3f\u75c5.\u4e3b\u306a\u4e8b\u5b9f\u300210 November 2021. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/diabetes<\/a>
2.\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2.\u6b7b\u56e0\u30c8\u30c3\u30d710.9 December 2020. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/the-top-10-causes-of-death<\/a>
3.\u6b27\u5dde\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e00\u6b21\u4e88\u9632\u306b\u304a\u3051\u308b\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u8102\u8cea\u7570\u5e38\u75c7\u306e\u6709\u75c5\u7387\u3068\u6cbb\u7642\uff1aEURIKA\u3001\u6a2a\u65ad\u89b3\u5bdf\u7814\u7a76\u3002BMC Cardiovasc Disord 17, 160 (2017). <\/td>\n<\/tr>\n
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