{"id":254354,"date":"2025-01-21T23:25:49","date_gmt":"2025-01-21T22:25:49","guid":{"rendered":"https:\/\/r3i.org\/%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-pesa%e7%a0%94%e7%a9%b6%ef%bc%9a%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%ae%e4%b8%8a%e6%98%87%e3%81%af%e6%bd%9c%e5%9c%a8\/"},"modified":"2025-02-16T22:27:58","modified_gmt":"2025-02-16T21:27:58","slug":"%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-pesa%e7%a0%94%e7%a9%b6%ef%bc%9a%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%ae%e4%b8%8a%e6%98%87%e3%81%af%e6%bd%9c%e5%9c%a8","status":"publish","type":"page","link":"https:\/\/r3i.org\/ja\/%e3%83%95%e3%82%a9%e3%83%bc%e3%82%ab%e3%82%b9-pesa%e7%a0%94%e7%a9%b6%ef%bc%9a%e3%83%88%e3%83%aa%e3%82%b0%e3%83%aa%e3%82%bb%e3%83%aa%e3%83%89%e3%81%ae%e4%b8%8a%e6%98%87%e3%81%af%e6%bd%9c%e5%9c%a8\/","title":{"rendered":"\u30d5\u30a9\u30fc\u30ab\u30b9 &#8211; PESA\u7814\u7a76\uff1a\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306e\u4e0a\u6607\u306f\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3068\u95a2\u9023\u3059\u308b"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;1px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_2_text_color=&#8221;gcid-primary-color&#8221; header_5_text_color=&#8221;gcid-secondary-color&#8221; text_orientation=&#8221;center&#8221; width=&#8221;99%&#8221; custom_margin=&#8221;|-147px||||&#8221; custom_padding=&#8221;|0px||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22header_2_text_color%22%93,%22gcid-secondary-color%22:%91%22header_5_text_color%22%93}&#8221; sticky_enabled=&#8221;0&#8243;]<h2>\u30d5\u30a9\u30fc\u30ab\u30b9 &#8211;<span>PESA\u7814\u7a76\uff1a\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306e\u4e0a\u6607\u306f\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3068\u95a2\u9023\u3059\u308b<\/span><\/h2>\n<h5><span>2021\u5e749\u67087\u65e5<\/span><\/h5>\n<p><em>\u3053\u306ePESA\uff08Progression of Early Subclinical Atherosclerosis\uff09\u8a66\u9a13\u306e\u5831\u544a\u3067\u306f\u3001\u305f\u3068\u3048\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u5024\u304c\u6b63\u5e38\u3067\u3042\u3063\u3066\u3082\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08TG\uff09\u5024150mg\/dL\uff081.7mmol\/L\uff09\u4ee5\u4e0a\u304c\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002<\/em><\/p>\n<p><em>\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3068\u6b8b\u5b58\u52d5\u8108\u786c\u5316\u30ea\u30b9\u30af\u3002J Am Coll Cardiol 2021;22: 3031 &#8211; 41.  <\/em><\/p>\n<p><b>\u7814\u7a76\u6982\u8981<\/b><\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\" width=\"17%\"><strong>\u76ee\u7684<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\" width=\"83%\">\u5065\u5e38\u4eba\u306b\u304a\u3051\u308b\u8840\u6e05TG\u5024\u3068\u65e9\u671f\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u304a\u3088\u3073\u8840\u7ba1\u708e\u75c7\u3068\u306e\u95a2\u9023\u3092\u8abf\u3079\u308b\u3053\u3068\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u8a08\u753b<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">PESA\u306f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u304a\u3088\u3073\u305d\u306e\u9032\u884c\u306e\u6c7a\u5b9a\u56e0\u5b50\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e\u89b3\u5bdf\u7684\u3001\u7e26\u65ad\u7684\u3001\u524d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u3042\u308b\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td valign=\"top\" bgcolor=\"#E9E9E9\"><strong>\u7814\u7a76\u5bfe\u8c61\u8005\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u3053\u306e\u89e3\u6790\u306f\u30012010\u5e746\u6708\u304b\u30892014\u5e742\u6708\u307e\u3067\u306b\u52df\u96c6\u3055\u308c\u305f\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u4f4e\uff0885\uff05\uff09\u301c\u4e2d\u7b49\u5ea6\u306e\u4e2d\u5e74\u80053,754\u4eba\uff08\u5e73\u5747\u5e74\u9f6245.5\u6b73\u3001\u7537\u602761\uff05\uff09\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3002\u5e73\u5747LDL-C\u5024\u306f133mg\/dL\uff1a27.8\uff05\u306e\u4eba\u304c\u3001\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u5b9a\u7fa9\u3055\u308c\u305f\u4e2d\u7b49\u5ea6\u304a\u3088\u3073\u4f4e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u6b63\u5e38\u7bc4\u56f2\uff08\u305d\u308c\u305e\u308c&lt;100\u304a\u3088\u3073&lt;116mg\/dL\uff09\u5185\u3067\u3042\u3063\u305f\u3002\u5e73\u5747\u8840\u6e05TG\u306f92.2mg\/dL\u3067\u300110.5\uff05\u304cTG\u2267150mg\/dL\u3067\u3042\u3063\u305f\u3002  <\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u4e3b\u306a\u7814\u7a76\u5909\u6570\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">&#8211; \u8840\u6e05TG\u3001150mg\/dL\u4ee5\u4e0a\u3068&lt;150mg\/dL\uff08&lt;100mg\/dL\u307e\u305f\u306f100\uff5e149mg\/dL\u306e\u3044\u305a\u308c\u304b\uff09\u306b\u5c64\u5225\u5316\u3002<br>&#8211; \u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u30d7\u30e9\u30fc\u30af\u306e\u5b58\u5728\u30012\u6b21\u5143\u8840\u7ba1\u8d85\u97f3\u6ce2\uff082D\uff09\u306b\u3088\u308a\u8a55\u4fa1<br>&#8211; \u51a0\u52d5\u8108\u30ab\u30eb\u30b7\u30a6\u30e0\u30b9\u30b3\u30a2\uff08CACS\uff09\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u65ad\u5c64\u64ae\u5f71\uff08CT\uff09\u306b\u3088\u308a\u6c7a\u5b9a<br>&#8211; \u8840\u7ba1\u708e\u75c7\u3001\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u578b\u30d5\u30c3\u7d20-18\u30d5\u30eb\u30aa\u30ed\u30c7\u30aa\u30ad\u30b7\u30b0\u30eb\u30b3\u30fc\u30b9\uff0818F-FDG\uff09\u967d\u96fb\u5b50\u653e\u5c04\u65ad\u5c64\u64ae\u5f71\uff08PET\uff09\u306b\u3088\u308a\u8a55\u4fa1\u3002<\/td>\n<\/tr>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u65b9\u6cd5\uff1a<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u8abf\u6574\u56de\u5e30\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3001TG\u3068\u51a0\u52d5\u8108\u4ee5\u5916\u306e\u52d5\u8108\u786c\u5316\u9818\u57df\u6570\u3068\u306e\u95a2\u4fc2\u3092\u8a55\u4fa1\u3057\u305f\u3002TG\u3068\u8840\u7ba1\u708e\u75c7\u3068\u306e\u95a2\u9023\u306f\u30ed\u30b8\u30b9\u30c6\u30a3\u30c3\u30af\u56de\u5e30\u3067\u8a55\u4fa1\u3057\u305f\u3002 <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: center;\"><strong>\u7d50\u679c<\/strong><\/p>\n<p>\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u30d7\u30e9\u30fc\u30af\u306e\u6709\u75c5\u7387\u306f\u3001TG\u30ab\u30c6\u30b4\u30ea\u30fc\u304c\u5897\u52a0\u3059\u308b\u306b\u3064\u308c\u3066\u6bb5\u968e\u7684\u306b\u5897\u52a0\u3057\u305f\uff08\u8868\uff09\u3002<\/p>\n<p><strong>\u8868.TG\u30ab\u30c6\u30b4\u30ea\u30fc\u5225\u306e\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u306e\u6709\u75c5\u7387\uff08\uff05\uff09\u3002 <\/strong><\/p>\n<table class=\"study-table\">\n<tbody>\n<tr>\n<td width=\"121\">\n<p><strong>&lt;100 mg\/dL<\/strong><\/p>\n<p><strong>(N=2580)<\/strong><\/p>\n<\/td>\n<td width=\"143\">\n<p><strong>100-149mg\/dL<\/strong><\/p>\n<p><strong>(N=781)<\/strong><\/p>\n<\/td>\n<td width=\"143\">\n<p><strong>\u2265150mg\/dl\u4ee5\u4e0a<\/strong><\/p>\n<p><strong>(N=393)<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"131\">\n<p>\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7(%)<\/p>\n<\/td>\n<td width=\"121\">\n<p>52.5<\/p>\n<\/td>\n<td width=\"143\">\n<p>68.8<\/p>\n<\/td>\n<td width=\"143\">\n<p>73.0<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"131\">\n<p> 1\u30c6\u30ea\u30c8\u30ea\u30fc<\/p>\n<p> 2\u3064\u306e\u9818\u571f<\/p>\n<p> \u22653\u3064\u306e\u9818\u571f<\/p>\n<\/td>\n<td width=\"121\">\n<p>47.5<\/p>\n<p>22.9<\/p>\n<p>29.6<\/p>\n<\/td>\n<td width=\"143\">\n<p>31.2<\/p>\n<p>23.8<\/p>\n<p>45.0<\/p>\n<\/td>\n<td width=\"143\">\n<p>27.0<\/p>\n<p>19.8<\/p>\n<p>53.2<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"131\">\n<p>\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7<\/p>\n<p>\u30aa\u30c3\u30ba\u6bd4\uff0895\uff05CI\uff09<\/p>\n<\/td>\n<td width=\"121\">\n<p>\u53c2\u8003<\/p>\n<\/td>\n<td width=\"143\">\n<p>1.16 (0.98-1.36)<\/p>\n<p>p=0.074<\/p>\n<\/td>\n<td width=\"143\">\n<p>1.35 (1.08-1.68)<\/p>\n<p>p=0.003<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>CI \u4fe1\u983c\u533a\u9593<\/p>\n<p>TG&lt;100mg\/dL\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u3001TG\u2267150mg\/dL\u306e\u4eba\u306f\u975e\u51a0\u52d5\u8108\u786c\u5316\u306e\u6709\u75c5\u7387\u304c\u9ad8\u304b\u3063\u305f\uff08\u30aa\u30c3\u30ba\u6bd41.35\u300195\uff05CI\uff1a1.08\uff5e1.68\u3001p= 0.008\uff09\u3002\u3053\u306e\u95a2\u9023\u306fLDL-C\u306e\u6fc3\u5ea6\u306b\u95a2\u4fc2\u306a\u304f\u660e\u3089\u304b\u3067\u3042\u3063\u305f\uff1aLDL-C\u304c\u9ad8\u3044\u4eba\u3067\u306f\u30aa\u30c3\u30ba\u6bd41.42\u300195\uff05CI\uff1a1.11\uff5e1.80\u3001LDL-C\u304c\u6b63\u5e38\u307e\u305f\u306f\u4f4e\u3044\u4eba\u3067\u306f\u30aa\u30c3\u30ba\u6bd41.85\u300195\uff05CI\uff1a1.08\uff5e3.18\u3002 <\/p>\n<p>TG150mg\/dl\u4ee5\u4e0a\u306e\u4eba\u306f\u52d5\u8108\u786c\u5316\u306e\u30ea\u30b9\u30af\u30822\u500d\u9ad8\u304b\u3063\u305f\u3002<span> <\/span><sup>18F-FDG\u306e<\/sup>\u53d6\u308a\u8fbc\u307f\uff08\u8abf\u6574\u30aa\u30c3\u30ba\u6bd42.09\u300195\uff05CI 1.29\u301c3.40\u3001p = 0.003\uff09\u306f\u3001TG&lt;100mg\/dL\u306e\u4eba\u3068\u6bd4\u8f03\u3057\u305f\u3002TG\u3068CACS\u306e\u9593\u306b\u306f\u95a2\u9023\u306f\u306a\u304b\u3063\u305f\u3002 <\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr valign=\"middle\">\n<td bgcolor=\"#E9E9E9\"><strong>\u8457\u8005\u306e\u7d50\u8ad6<\/strong><\/td>\n<td align=\"left\" bgcolor=\"#FFFFFF\">\u4f4e\uff5e\u4e2d\u7b49\u5ea6\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u6709\u3059\u308b\u60a3\u8005\u3067\u306f\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306f\u3001LDL-C\u5024\u304c\u6b63\u5e38\u3067\u3042\u3063\u3066\u3082\u3001\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u304a\u3088\u3073\u8840\u7ba1\u708e\u75c7\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div>\n<p><strong>\u30b3\u30e1\u30f3\u30c8<\/strong><\/p>\n<p>\u52d5\u8108\u786c\u5316\u306e\u539f\u56e0\u7d4c\u8def\u306b\u304a\u3051\u308bTG\u4e0a\u6607\uff08TG\u30ea\u30c3\u30c1\u30ea\u30dd\u86cb\u767d\u3068\u305d\u306e\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8ca0\u8377\u91cf\u306e\u4ee3\u7528\uff09\u306e\u5f79\u5272\u3092\u652f\u6301\u3059\u308b\u8a3c\u62e0\u304c\u84c4\u7a4d\u3055\u308c\u3064\u3064\u3042\u308b(1,2)\u3002\u3057\u304b\u3057\u3001TG\u306e\u4e0a\u6607\u304c\u81e8\u5e8a\u7684\u306b\u554f\u984c\u3068\u306a\u308b\u30ec\u30d9\u30eb\u306b\u3064\u3044\u3066\u306f\u3001\u4f9d\u7136\u3068\u3057\u3066\u4e0d\u660e\u78ba\u306a\u70b9\u304c\u591a\u3044\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u4f4e\u30ea\u30b9\u30af\u306e\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u65e9\u671f\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u306eTG\u3068\u6f5c\u5728\u6027\u52d5\u8108\u786c\u5316\u75c7\u304a\u3088\u3073\u8840\u7ba1\u708e\u75c7\u3068\u306e\u95a2\u9023\u3092\u8abf\u3079\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u3053\u306e\u7591\u554f\u306b\u5bfe\u3059\u308b\u6d1e\u5bdf\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002\u3053\u306e\u5831\u544a\u3067\u7528\u3044\u305fPESA\u30b3\u30db\u30fc\u30c8\u306f\u3001\u5927\u591a\u6570\uff0885\uff05\uff09\u304c\u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u4f4e\u3044\u4eba\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u9069\u5207\u306a\u3082\u306e\u3067\u3042\u3063\u305f\u3002   <\/p>\n<p>\u672c\u7814\u7a76\u306e\u7d50\u679c\u306f\u3001TG 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  <\/p>\n<\/div>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"3\" bgcolor=\"#CCCCCC\">\n<tbody>\n<tr>\n<td valign=\"top\" bgcolor=\"#E9E9E9\" width=\"13%\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/td>\n<td valign=\"top\" bgcolor=\"#FFFFFF\" width=\"87%\">1.Nordestgaard BG\u3002Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology.Circ Res 2016;118:547-63.<br>2.Sandesara PB, Virani SS, Fazio S, Shapiro MD.\u5fd8\u308c\u3089\u308c\u305f\u8102\u8cea\uff1a\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3001\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u3002Endocr Rev 2019;40:537-57.<br>3.Mach F, Baigent C, Catapano AL, et al. 2019 ESC\/EAS Guidelines for the Management of dyslipidaemias: lipid modification to reduce cardiovascular risk.Eur Heart J 2020;41:111-88.<br>4.Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study\u306e\u6839\u62e0\u3068\u30c7\u30b6\u30a4\u30f3\u3002Am Heart J 2018;206:80-93.       <\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" bgcolor=\"#E9E9E9\"><strong>\u30ad\u30fc\u30ef\u30fc\u30c9<\/strong><\/td>\n<td valign=\"top\" bgcolor=\"#FFFFFF\">\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1b\u76f4\u63a5\u6e2c\u5b9a\uff1b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\uff1bPROMINENT<\/td>\n<\/tr>\n<\/tbody>\n<\/table>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>\u30d5\u30a9\u30fc\u30ab\u30b9 -PESA\u7814\u7a76\uff1a\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u306e\u4e0a\u6607\u306f\u6f5c\u5728\u6027\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u3068\u95a2\u9023\u3059\u308b 2021\u5e749\u67087\u65e5  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