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R3i\u30e9\u30f3\u30c9\u30de\u30fc\u30af<\/h2>\n

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\u6700\u65b0\u306e\u30e9\u30f3\u30c9\u30de\u30fc\u30af<\/h2>\n

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REDUCE-IT\u304b\u3089\u306e\u65b0\u77e5\u898b\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u6cbb\u7642\u304c\u7dcf\u75be\u75c5\u8ca0\u8377\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059<\/h5>\n
2026\u5e742\u6708<\/h6>\n

\u3053\u306e\u89e3\u6790\u7d50\u679c\u306f\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u9178\u30a8\u30c1\u30eb\u306b\u3088\u308b\u6cbb\u7642\u306f\u3001\u9ad8\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u6709\u3059\u308b\u500b\u4eba\u306b\u304a\u3051\u308b\u5165\u9662\u304a\u3088\u3073\u5165\u9662\u671f\u9593\u3092\u77ed\u7e2e\u3055\u305b\u3001\u81e8\u5e8a\u7684\u304a\u3088\u3073\u60a3\u8005\u4e2d\u5fc3\u7684\u5229\u76ca\u306e\u4e21\u65b9\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3002
Szarek M, Bhatt DL, Miller M, et al. Effects of icosapent ethyl on risk and duration of hospitalizations and death in REDUCE-IT. Eur J Prev Cardiol 2026: doi: 10.1093\/eurjpc\/zwag040. <\/em><\/p>\n

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\u305d\u306e\u4ed6\u306e\u30e9\u30f3\u30c9\u30de\u30fc\u30af<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2025 <\/span><\/h2>\n

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FOURIER\u304b\u3089\u306e\u6d1e\u5bdf\uff1a\u80a5\u6e80\u306b\u95a2\u9023\u3059\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af<\/h5>\n
2025\u5e7412\u6708<\/h6>\n

Evolocumab\u6cbb\u7642\u306f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u6709\u3059\u308b\u80a5\u6e80\u60a3\u8005\u306b\u304a\u3044\u3066\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3057\u305f\u3002
\u51fa\u5178\uff1a Kang YM, Giugliano RP, Keech AC, et al. Obesity-associated cardiovascular risk and benefit from PCSK9 inhibition. A prespecified analysis from FOURIER. J Am Coll Cardiol 2025; doi.org\/10.1016\/j.jacc.2025.10.036. <\/p>\n

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VESALIUS-CV\uff1a\u6a19\u6e96\u7684\u306a\u8102\u8cea\u4f4e\u4e0b\u7642\u6cd5\u306b\u30a8\u30dc\u30ed\u30af\u30de\u30d6\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u6700\u521d\u306e\u91cd\u5927\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u4e88\u9632\u3055\u308c\u308b<\/h5>\n
November 2025<\/h6>\n

PCKS9\u963b\u5bb3\u85ac\u30a8\u30dc\u30ed\u30af\u30de\u30d6\u3068\u6a19\u6e96\u7684\u306a\u8102\u8cea\u4f4e\u4e0b\u7642\u6cd5\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u6210\u4eba\uff08\u52d5\u8108\u786c\u5316\u304c\u8a8d\u3081\u3089\u308c\u308b\u304b\u3001\u9ad8\u30ea\u30b9\u30af\u306e\u7cd6\u5c3f\u75c5\u3092\u6709\u3059\u308b\uff09\u3067\u3001\u5fc3\u7b4b\u6897\u585e\u3084\u8133\u5352\u4e2d\u306e\u65e2\u5f80\u304c\u306a\u3044\u5834\u5408\u3001\u6700\u521d\u306e\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c25\uff05\u6e1b\u5c11\u3057\u305f\u3002 <\/em><\/p>\n

Bohula EA, Marston NA, Bhatia AK, et al. Evolocumab in patients without a previous myocardial Infarction or stroke. N Engl J Med 2025; DOI: 10.1056\/NEJMoa2514428. <\/em><\/p>\n

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\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u60a3\u8005\u306b\u304a\u3051\u308b\u30ea\u30dd\u86cb\u767d(a)\u4e0a\u6607\u306e\u6a19\u7684<\/h5>\n
2025\u5e7410\u6708<\/h6>\n

\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u3068\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u9ad8\u5024\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a2\u30ea\u30ed\u30af\u30de\u30d6\u6295\u4e0e\u306b\u3088\u308a\u3001\u4e3b\u8981\u306a\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3068\u56db\u80a2\u306e\u6709\u5bb3\u30a4\u30d9\u30f3\u30c8\u306e\u4e21\u65b9\u306e\u30ea\u30b9\u30af\u304c\u3088\u308a\u65e9\u671f\u306b\u3001\u3088\u308a\u5927\u304d\u304f\u6e1b\u5c11\u3057\u305f\uff1aODYSSEY OUTCOMES\u304b\u3089\u306e\u77e5\u898b\u3002
Ray KK, Szarek M, Bhatt DL, et al. Lipoprotein(a) identifies patients with acute coronary syndromes who derive cardiovascular benefit from alirocumab, particularly for limb events. J Am Coll Cardiol 2025; https:\/\/doi.org\/10.1016\/j.jacc.2025.08.043<\/a> <\/p>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1NjEzNiIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”-21px|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”||20px||false|false” custom_padding=”||6px|||” border_radii=”off|13px|13px|13px|13px” border_color_all=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” border_width_all_tablet=”4px” border_width_all_phone=”0px” border_width_all_last_edited=”on|phone” border_color_all_tablet=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” border_color_all_phone=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” border_color_all_last_edited=”on|phone” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22border_color_all%22,%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”14px” header_5_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_5_font_size=”21px” header_6_text_color=”gcid-secondary-color” custom_padding=”|||14px||” header_5_font_size_tablet=”35px” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_5_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

STRENGTH\u8a66\u9a13\u306f\u30a2\u30b8\u30a2\u4eba\u60a3\u8005\u306b\u304a\u3051\u308b\u6709\u76ca\u6027\u3092\u793a\u5506<\/h5>\n
2025\u5e749\u6708<\/h6>\n

\u4e2d\u7acb\u7684\u306aSTRENGTH\u8a66\u9a13\u306e\u63a2\u7d22\u7684\u89e3\u6790\u306b\u3088\u308b\u3068\u3001\u30aa\u30e1\u30ac-3\uff08\u03c9-3\uff09\u30ab\u30eb\u30dc\u30f3\u9178\u88fd\u5264\u306b\u3088\u308b\u6cbb\u7642\u306f\u3001\u30a2\u30b8\u30a2\u4eba\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u306a\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u6709\u610f\u306a\u6e1b\u5c11\u306b\u95a2\u9023\u3057\u305f\u304c\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u975e\u30a2\u30b8\u30a2\u4eba\u60a3\u8005\u3067\u306f\u95a2\u9023\u3057\u306a\u304b\u3063\u305f\u3002<\/em><\/p>\n

Wang TKM, Nicholls SJ, St John J, et al. Differential cardiovascular impact of \u03c9-3 fatty acid in patients at high cardiovascular risk in Asians versus non-Asians: Sub-analysis of the STRENGTH randomized clinical trial. Atherosclerosis 2025; <\/em> <\/span>https:\/\/doi.org\/10.1016\/j.atherosclerosis.2025.120228<\/a>.<\/em><\/p>\n

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REDUCE-IT\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306f\u4f4eLDL-C\u3067\u3082\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b<\/h5>\n
2025\u5e748\u6708<\/h6>\n

\u3053\u306eREDUCE-IT\u306e\u89e3\u6790\u3067\u306f\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u9ad8\u7528\u91cf\u6295\u4e0e\u306b\u3088\u308a\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304c\u9ad8\u5024\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u305f\u3068\u3048\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u304c\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u63a8\u5968\u76ee\u6a19\u5024\u4ee5\u4e0b\u3067\u3042\u3063\u3066\u3082\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c34\uff05\u6e1b\u5c11\u3057\u305f\u3002<\/p>\n

Aggarwal R, Bhatt DL, Steg PG, et al. Cardiovascular outcomes with icosapent ethyl by baseline low-density lipoprotein cholesterol: a secondary analysis of the REDUCE-IT randomized trial. J Am Heart Assoc. 2025;14(5):e038656. <\/em><\/p>\n

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LoDoCo2\uff08\u4f4e\u7528\u91cf\u30b3\u30eb\u30d2\u30c1\u30f32\uff09\u8a66\u9a13\u304b\u3089\u306e\u8003\u5bdf<\/h5>\n
2025\u5e747\u6708<\/h6>\n

\u3053\u306e\u6700\u65b0\u306e\u89e3\u6790\u306f<\/span><\/i> \u6162\u6027\u51a0\u75c7\u5019\u7fa4\u60a3\u8005\u306b\u304a\u3051\u308b\u30b3\u30eb\u30d2\u30c1\u30f3\u306e\u4f7f\u7528\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ea\u30b9\u30af\u306e\u7bc4\u56f2\u306b\u308f\u305f\u3063\u3066\u652f\u6301\u3055\u308c\u308b\u3002 <\/span><\/i> <\/p>\n

Mohammadnia N, Wesselink BE, Bax WA, et al. Cardiovascular benefit of colchicine in relation to baseline risk: a secondary analysis of the LoDoCo2 Trial. J Am Heart Assoc 2025;14:e038687. DOI: 10.1161\/JAHA.124.038687. <\/span><\/i><\/p>\n

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\u5b50\u4f9b\u3068\u9752\u5c11\u5e74\u306e\u4e16\u754c\u7684\u306a\u80a5\u6e80\u306b\u53d6\u308a\u7d44\u3080\u305f\u3081\u306b\u65e9\u6025\u306a\u5bfe\u7b56\u304c\u5fc5\u8981<\/h5>\n
2025\u5e744\u6708<\/h6>\n

Global Burden of Disease Study 2021\u306e\u6700\u65b0\u30c7\u30fc\u30bf\u306f\u3001\u5b50\u4f9b\u3068\u9752\u5c11\u5e74\u306b\u304a\u3051\u308b\u80a5\u6e80\u306e\u4e16\u754c\u7684\u6d41\u884c\u3092\u6d6e\u304d\u5f6b\u308a\u306b\u3057\u3066\u3044\u308b\u3002\u4e88\u6e2c\u30c7\u30fc\u30bf\u306b\u3088\u308b\u3068\u3001\u4eca\u3059\u3050\u306b\u7dca\u6025\u306e\u5bfe\u7b56\u3092\u8b1b\u3058\u306a\u3044\u9650\u308a\u30012050\u5e74\u307e\u3067\u306b\u5b50\u4f9b\u3068\u9752\u5c11\u5e74\u306e\u7d043\u5206\u306e1\u304c\u592a\u308a\u3059\u304e\u304b\u80a5\u6e80\u306b\u306a\u308b\u3068\u3044\u3046\u3002 <\/span><\/i><\/p>\n

GBD 2021 Adolescent BMI Collaborators. Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990\u20132021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021. Lancet 2025; 405: 785\u2013812 <\/span><\/i><\/p>\n

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2024 <\/span><\/h2>\n

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PROMINENT\u304b\u3089\u306e\u6d1e\u5bdf\uff1a\u30da\u30de\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\u304c2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u6f70\u760d\u307e\u305f\u306f\u58ca\u75bd\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u5c11\u3055\u305b\u308b<\/h3>\n

2024\u5e748\u6708<\/span><\/h6>\n
\n

PROMINENT\u8a66\u9a13\u3067\u5f97\u3089\u308c\u305f\u3053\u308c\u3089\u306e\u6240\u898b\u304b\u3089\u3001\u30da\u30de\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\u306f2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u4e0b\u80a2\u865a\u8840\u6027\u6f70\u760d\u304a\u3088\u3073\u58ca\u75bd\u3092\u6e1b\u5c11\u3055\u305b\u308b\u6cbb\u7642\u7684\u53ef\u80fd\u6027\uff08
\uff09\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u308b\u3002<\/p>\n

Marinho LL, Everett BM, Aday AW, et al. Effect of pemafibrate on diabetic foot ulceration and
gangrene. An exploratory analysis from PROMINENT. J Am Coll Cardiol 2024;84:408-410. <\/p>\n<\/div>\n

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REDUCE-IT\uff1a\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u306b\u304a\u3051\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb<\/h3>\n

2024\u5e747\u6708<\/span><\/h6>\n
REDUCE-IT\uff08Reduction of Cardiovascular Events with
Icosapent Ethyl-Intervention Trial\uff09\u306epost hoc\u89e3\u6790\u306b\u3088\u308b\u3068\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u6295\u4e0e\u306f\u3001\u6700\u8fd1\uff0812\u30f5\u6708\u672a\u6e80\uff09\u6025\u6027\u51a0\u75c7\u5019\u7fa4\uff08ACS\uff09\u3092\u767a\u75c7\u3057\u305f\u9ad8\u30ea\u30b9\u30af\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u51fa\u8840\u3092\u4f34\u3046\u3053\u3068\u306a\u304f\u865a\u8840\u6027\u30a4\u30d9\u30f3\u30c8\uff08
\uff09\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u5c11\u3055\u305b\u305f\u3002
\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u5f8c\u306e\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\uff1aREDUCE-IT\u8a66\u9a13 <\/em>
\u8a66\u9a13\u3067\u3042\u308b\u3002Eur Heart J 2024; 45: 1173-76. <\/em><\/div>\n

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REDUCE-IT\u3088\u308a\uff1a\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u306f\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u30ea\u30b9\u30af\u8efd\u6e1b\u3092\u4fee\u98fe\u3059\u308b\u304b\uff1f<\/span><\/h3>\n
2024\u5e746\u670827\u65e5<\/span><\/h6>\n
REDUCE-IT\uff08Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial\uff09\u306e\u4e8b\u5f8c\u89e3\u6790\u306b\u304a\u3044\u3066\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306f\u3001\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306aLp(a)\u5024\u4e0a\u6607\u60a3\u8005\u3092\u542b\u3081\u3001\u30ea\u30dd\u86cb\u767d(a)\uff3bLp(a)\uff3d\u5024\u306e\u7bc4\u56f2\u306b\u308f\u305f\u3063\u3066\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u306e\u30ea\u30b9\u30af\u3092\u4e00\u8cab\u3057\u3066\u6e1b\u5c11\u3055\u305b\u305f\u3002<\/div>\n
\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u8840\u4e2d\u6fc3\u5ea6\u3068\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u3002J Am Coll Cardiol 2024; 83:1529-39. <\/em><\/div>\n

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REDUCE-IT\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u6700\u5927\u306e\u30ea\u30b9\u30af\u6700\u5927\u306e\u5229\u76ca<\/h3>\n

2024\u5e745\u6708<\/span><\/h6>\n
REDUCE-IT\uff08Reduction of Cardiovascular Events with Icosapent
Ethyl-Intervention Trial\uff09\u306e\u6700\u65b0\u89e3\u6790\u306b\u304a\u3044\u3066\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u306e\u7bc4\u56f2\u306b\u308f\u305f\u3063\u3066\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u60a3\uff08ASCVD\uff09\u304a\u3088\u3073
\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4e0a\u6607\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u4e3b\u8981\u6709\u5bb3\u4e8b\u8c61\uff08MACE\uff09\u306e\u30ea\u30b9\u30af\u3092\u4e00\u8cab\u3057\u3066\u6e1b\u5c11\u3055\u305b\u305f\u3002\u3057\u304b\u3057\u3001\u6cbb\u7642\u52b9\u679c\u306e\u7d76\u5bfe\u5024
\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3067\u5927\u304d\u304b\u3063\u305f\u3002
Burger PM, Bhatt DL, Dorresteijn JAN, et al. Effects of icosapent ethyl according to baseline residual <\/em>
\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30ea\u30b9\u30af\uff1aREDUCE-IT\u306e\u7d50\u679c\u3002Eur Heart J <\/em>
Cardiovasc Pharmacother 2024; doi: 10.1093\/ehjcvp\/pvae030.<\/em><\/div>\n

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\u975eHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u9ad8\u6b8b\u7559\u30ea\u30b9\u30af\u306e\u8eab\u8fd1\u306a\u30de\u30fc\u30ab\u30fc<\/span><\/h3>\n
2024\u5e745\u670820\u65e5<\/span><\/h6>\n
\n
\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3092\u6709\u3057\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u5024\u304c\u826f\u597d\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u308b\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u800523,000\u4eba\u4ee5\u4e0a\u3092\u542b\u3080\u3053\u306e\u7814\u7a76\u306f\u3001\u975e\u9ad8\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08non-HDL-C\uff09\u304c\u3001\u6b8b\u5b58\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u3092\u540c\u5b9a\u3059\u308b\u305f\u3081\u306e\u7c21\u4fbf\u3067\u9811\u5065\u306a\u6307\u6a19\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u305f\u3002<\/div>\n
\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3067LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u826f\u597d\u306a\u60a3\u8005\u306b\u304a\u3051\u308b\u975eHDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u6b8b\u5b58\u30ea\u30b9\u30af\uff1a\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3002Lancet Regional Health – Europe 2024;36: 100774. <\/em><\/div>\n<\/div>\n

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\u30ea\u30dd\u86cb\u767d(a)\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u65b0\u898fsiRNA\u306e\u521d\u306e\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13<\/span><\/h3>\n
2024\u5e743\u670812\u65e5<\/span><\/h6>\n
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\u65b0\u898f\u306e\u77ed\u9396\u5e72\u6e09\u6027RNA\uff08siRNA\uff09\u3067\u3042\u308b\u30ec\u30dd\u30b8\u30b7\u30e9\u30f3\u306f\u3001\u6700\u9ad8\u5358\u56de\u6295\u4e0e\u3067\u30ea\u30dd\u86cb\u767d\uff08a\uff09\uff3bLp\uff08a\uff09\uff3d\u6fc3\u5ea6\u309297\uff05\u4f4e\u4e0b\u3055\u305b\u3001\u305d\u306e\u52b9\u679c\u306f\u9577\u671f\u306b\u308f\u305f\u3063\u3066\u6301\u7d9a\u3057\u305f\u3002<\/div>\n
Nissen SE, Linnebjerg H, Shen X, et al. Lepodisiran, an extended-duration short interfering RNA targeting lipoprotein(a): a randomized dose-ascending clinical trial.JAMA 2023;330:2075-83. <\/em><\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MDQ3MSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u7d4c\u53e3\u4f4e\u5206\u5b50\u30ea\u30dd\u86cb\u767d(a)\u5f62\u6210\u963b\u5bb3\u85acmuvalaplin\u306e\u6700\u521d\u306e\u30c7\u30fc\u30bf<\/span><\/h3>\n
2024\u5e741\u67088\u65e5<\/span><\/h6>\n
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\u3053\u306e\u7b2cI\u76f8\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u30e0\u30d0\u30e9\u30d7\u30ea\u30f3\u306f\u5b89\u5168\u6027\u306e\u61f8\u5ff5\u306a\u3057\u306b\u30ea\u30dd\u86cb\u767d(a)\uff3bLp(a)\uff3d\u5024\u3092\u6700\u592765\uff05\u4f4e\u4e0b\u3055\u305b\u3001\u3055\u3089\u306a\u308b\u81e8\u5e8a\u958b\u767a\u306e\u57fa\u76e4\u3092\u63d0\u4f9b\u3057\u305f\u3002<\/div>\n
Nicholls SJ\u3001Nissen SE\u3001Fleming C\u3001\u4ed6\u3002\u7d4c\u53e3\u4f4e\u5206\u5b50\u30ea\u30dd\u86cb\u767d\uff08a\uff09\u5f62\u6210\u963b\u5bb3\u85acMuvalaplin\uff1a\u7121\u4f5c\u70ba\u5316\u81e8\u5e8a\u8a66\u9a13\u3002doi: 10.1001\/jama.2023.16503. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MDQ3OCIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2023 <\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5fc3\u8840\u7ba1\u8ee2\u5e30\u3092\u95a2\u9023\u4ed8\u3051\u308b\u3088\u308a\u591a\u304f\u306e\u8a3c\u62e0<\/span><\/h3>\n
2023\u5e749\u670826\u65e5<\/span><\/h6>\n
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90\u4e07\u4eba\u4ee5\u4e0a\u306e\u88ab\u9a13\u8005\u3092\u542b\u3080\u3053\u306e\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u7814\u7a76\u3067\u306f\u3001\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3068\u5fc3\u8840\u7ba1\u7cfb\u306e\u8ee2\u5e30\u3068\u306e\u9593\u306b\u907a\u4f1d\u7684\u56e0\u679c\u95a2\u4fc2\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/div>\n
\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u7cfb\u306e\u8ee2\u5e30\u306b\u5bfe\u3059\u308b\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u72ec\u7acb\u56e0\u679c\u95a2\u4fc2\uff1a\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u7814\u7a76\u3002Arterioscler Thromb Vasc Biol 2023; doi: 10.1161\/ATVBAHA.123.319297. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MDQ4NyIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

CLEAR\uff08ACL\u963b\u5bb3\u30ec\u30b8\u30e1\u30f3\u3067\u3042\u308b\u30d9\u30f3\u30da\u30c9\u9178[ECT1002]\u306b\u3088\u308b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\uff09\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u30b9\u30bf\u30c1\u30f3\u4e0d\u8010\u6027\u306e\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u30d9\u30f3\u30da\u30c9\u9178\u306e\u5f79\u5272<\/span><\/h3>\n
6 2023\u5e747\u6708<\/h6>\n
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\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u306b\u8010\u3048\u3089\u308c\u306a\u3044\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30d9\u30e0\u30da\u30c9\u9178\u306b\u3088\u308b\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u306e\u4f4e\u4e0b\u304c\u3001\u4e3b\u8981\u306a\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u305f\u3002<\/div>\n
Nissen SE\u3001Lincoff AM\u3001Brennan D\u3089\uff1a\u30b9\u30bf\u30c1\u30f3\u4e0d\u8010\u6027\u60a3\u8005\u306b\u304a\u3051\u308b\u30d9\u30f3\u30da\u30c9\u9178\u3068\u5fc3\u8840\u7ba1\u8ee2\u5e30\u3002N Engl J Med 2023; DOI: 10.1056\/NEJMoa2215024 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MzM2MyIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

EMPA-KIDNEY\u8a66\u9a13\uff08\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306b\u3088\u308b\u5fc3\u81d3\u30fb\u814e\u81d3\u4fdd\u8b77\u8a66\u9a13\uff09\uff1a\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u304c\u6162\u6027\u814e\u81d3\u75c5\u60a3\u8005\u306b\u304a\u3044\u3066\u814e\u81d3\u304a\u3088\u3073\u5fc3\u8840\u7ba1\u306b\u6709\u7528\u6027\u3092\u793a\u3059<\/span><\/h3>\n
13 2023\u5e744\u6708<\/span><\/h6>\n
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\u75be\u60a3\u9032\u884c\u30ea\u30b9\u30af\u306e\u3042\u308b\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306e\u6295\u4e0e\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u3001\u814e\u81d3\u75c5\u306e\u9032\u884c\u307e\u305f\u306f\u5fc3\u8840\u7ba1\u7cfb\u306e\u539f\u56e0\u306b\u3088\u308b\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002<\/div>\n
EMPA-KIDNEY Collaborative Group; Herrington WG, Staplin N, Wanner C, et al. \u6162\u6027\u814e\u81d3\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u3002N Engl J Med 2022; doi: 10.1056\/NEJMoa2204233. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MDUwOCIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2022 <\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u30d7\u30ed\u30df\u30cd\u30f3\u30c8\u306e\u7d50\u679c\u304c\u51fa\u305f<\/span><\/h3>\n
6 2022\u5e7412\u6708<\/span><\/h6>\n
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PROMINENT\uff08Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabetes\uff1a\u30da\u30de\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\u306b\u3088\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4f4e\u4e0b\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u6291\u5236\uff09\u3067\u306f\u30012\u578b\u7cd6\u5c3f\u75c5\u3068\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30b9\u30bf\u30c1\u30f3\u306b\u3088\u308b\u5f37\u529b\u306a\u6cbb\u7642\u306b\u52a0\u3048\u3066\u30da\u30de\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\u3067\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u5024\u309226\uff05\u4f4e\u4e0b\u3055\u305b\u3066\u3082\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306f\u6709\u610f\u306b\u6e1b\u5c11\u3057\u306a\u304b\u3063\u305f\u3002\u3057\u304b\u3057\u3001\u63a2\u7d22\u7684\u30c7\u30fc\u30bf\u304b\u3089\u3001\u3053\u306e\u6cbb\u7642\u6cd5\u306f\u975e\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u8102\u80aa\u6027\u809d\u75be\u60a3\uff08NAFLD\uff09\u306b\u304a\u3044\u3066\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\u3002 <\/div>\n
\u30d7\u30e9\u30c0\u30f3AD\u3001\u30b0\u30ea\u30f3RJ\u3001\u30d5\u30eb\u30c1\u30e3\u30fc\u30c8JC\u3001\u4ed6\uff1a\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u8efd\u6e1b\u306e\u305f\u3081\u306e\u30da\u30de\u30d5\u30a3\u30d6\u30e9\u30fc\u30c8\u306b\u3088\u308b\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4f4e\u4e0b\u3002New Engl J Med 2022; DOI: 10.1056\/NEJMoa2210645 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MDUxNiIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u30aa\u30c7\u30c3\u30bb\u30a4\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u30a2\u30dd\u30ea\u30dd\u86cb\u767dB\u306f\u6b8b\u5b58\u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u5897\u5206\u60c5\u5831\u3092\u63d0\u4f9b\u3059\u308b<\/span><\/h3>\n
21 2022\u5e749\u6708<\/span><\/h6>\n
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ODYSSEY OUTCOMES\u8a66\u9a13\uff08Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab\uff09\u306e\u65b0\u305f\u306a\u89e3\u6790\u7d50\u679c\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u4e2d\u306e\u6025\u6027\u51a0\u75c7\u5019\u7fa4\uff08ACS\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u30ea\u30dd\u86cb\u767d\u306e\u6f38\u5897\u7684\u96c6\u4e2d\u7684\u4f4e\u4e0b\u3092\u884c\u3046\u969b\u306e\u76ee\u5b89\u3068\u3057\u3066\u30a2\u30dd\u30ea\u30dd\u86cb\u767dB\uff08apoB\uff09\u3092\u7528\u3044\u308b\u3053\u3068\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u3002<\/span><\/div>\n
Hagstr\u00f6m E, Steg PG, Szarek M, et al. \u30a2\u30dd\u30ea\u30dd\u86cb\u767dB\u3001\u6025\u6027\u51a0\u75c7\u5019\u7fa4\u5f8c\u306e\u5fc3\u8840\u7ba1\u6b8b\u5b58\u30ea\u30b9\u30af\u3001\u30a2\u30ea\u30ed\u30af\u30de\u30d6\u306e\u52b9\u679c\u3002\u30b5\u30fc\u30ad\u30e5\u30ec\u30fc\u30b7\u30e7\u30f32022\u5e746\u670830\u65e5\uff1a101161CIRCULATIONAHA121057807\u3002 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTc2MyIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

EMPA-KIDNEY\u8a66\u9a13\u306f\u6709\u52b9\u6027\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u305f\u3081\u65e9\u671f\u306b\u4e2d\u6b62\u3055\u308c\u305f<\/span><\/h3>\n
19 2022\u5e747\u6708<\/span><\/h6>\n
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EMPA-KIDNEY\uff08ClinicalTrials.gov\u8b58\u5225\u5b50\uff1aNCT03594110\uff09\u306f\u3001\u30ca\u30c8\u30ea\u30a6\u30e0-\u30b0\u30eb\u30b3\u30fc\u30b9\u5171\u8f38\u9001\u4f53-2\uff08SGLT-2\uff09\u963b\u5bb3\u85ac\u3067\u3042\u308b\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u304c\u3001\u6162\u6027\u814e\u81d3\u75c5\uff08CKD\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u814e\u81d3\u75c5\u306e\u9032\u884c\u307e\u305f\u306f\u5fc3\u8840\u7ba1\u6b7b\u3092\u4e88\u9632\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a3c\u3057\u3066\u3044\u305f\u3002\u672c\u8a66\u9a13\u306f\u3001\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u304c\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u3082\u6709\u52b9\u3067\u3042\u308b\u3068\u3044\u3046\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5f97\u3089\u308c\u305f\u305f\u3081\u3001\u72ec\u7acb\u30c7\u30fc\u30bf\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u59d4\u54e1\u4f1a\u306e\u52e7\u544a\u306b\u3088\u308a3\u670816\u65e5\u306b\u4e2d\u6b62\u3055\u308c\u305f\u3002 <\/span><\/div>\n
\u30a8\u30f3\u30d1-\u30ad\u30c9\u30cb\u30fc https:\/\/www.empakidney.org\/news\/empa-kidney-trial-stops-early-due-to-evidence-of-efficacy<\/a>.<\/em><\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTc3MCIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2021 <\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u65b0\u305f\u306a\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308a\u30012\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u30ea\u30b9\u30af\u306b\u5bfe\u3059\u308b\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u304c\u518d\u78ba\u8a8d\u3055\u308c\u308b<\/span><\/h3>\n
2 2021\u5e7411\u6708<\/span><\/h6>\n
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6\u4e07\u4eba\u4ee5\u4e0a\u306e2\u578b\u7cd6\u5c3f\u75c5\uff08T2DM\uff09\u60a3\u8005\u306e\u30c7\u30fc\u30bf\u3092\u542b\u3080\u3053\u306e\u6700\u65b0\u306e\u5831\u544a\u3067\u306f\u3001\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff08GLP-1\uff09\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3001\u5168\u6b7b\u4ea1\u3001\u5fc3\u4e0d\u5168\u306b\u3088\u308b\u5165\u9662\u3001\u814e\u6a5f\u80fd\u60aa\u5316\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/span><\/div>\n
Sattar N, Lee MMY, Kristensen SL, et al. 2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u3001\u6b7b\u4ea1\u7387\u3001\u814e\u81d3\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\uff1a\u7121\u4f5c\u70ba\u5316\u8a66\u9a13\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3068\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3002Lancet Diabetes Endocrinol 2021; doi: 10.1016\/S2213-8587(21)00203-5.Online ahead of print. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTc3NiIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u30b9\u30c8\u30ec\u30f3\u30b0\u30b9\u3067\u5fc3\u8840\u7ba1\u7cfb\u306b\u52b9\u679c\u304c\u306a\u3044\u7406\u7531\u3092\u63a2\u308b<\/span><\/h3>\n
2021\u5e749\u67087\u65e5<\/span><\/h6>\n
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STRENGTH\u306e\u65b0\u3057\u3044\u89e3\u6790\u3067\u306f\u3001\u30a8\u30a4\u30b3\u30b5\u30da\u30f3\u30bf\u30a8\u30f3\u9178\uff08EPA\uff09\u304a\u3088\u3073\u30c9\u30b3\u30b5\u30d8\u30ad\u30b5\u30a8\u30f3\u9178\uff08DHA\uff09\u306e\u9054\u6210\u30ec\u30d9\u30eb\u3068\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u7cfb\u306e\u8ee2\u5e30\u3068\u306e\u9593\u306b\u95a2\u9023\u306f\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/span><\/div>\n
Nissen SE, Lincoff AM, Wolski K, et al. \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u304a\u3051\u308b\u9054\u6210\u03c9-3\u8102\u80aa\u9178\u30ec\u30d9\u30eb\u3068\u4e3b\u8981\u306a\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u306e\u95a2\u9023\u3002STRENGTH Trial\u306e\u4e8c\u6b21\u89e3\u6790\u3002JAMA Cardiol 2021; doi:10.1001\/jamacardio.2021.1157 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTc4NSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

REDUCE-IT\u304b\u3089\u306e\u30cb\u30e5\u30fc\u30b9\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u304c\u865a\u8840\u6027\u8133\u6897\u585e\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u5c11\u3055\u305b\u308b<\/span><\/h3>\n
9 2021\u5e748\u6708<\/span><\/h6>\n
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REDUCE-IT\u306e\u65b0\u3057\u3044\u89e3\u6790\u306b\u3088\u308b\u3068\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u6cbb\u7642\u306f\u3001\u6700\u521d\u306e\u865a\u8840\u6027\u8133\u5352\u4e2d\u306e\u30ea\u30b9\u30af\u309236\uff05\u6e1b\u5c11\u3055\u305b\u308b\u3002<\/span><\/div>\n
Bhatt DL, Steg PG, Miller M, et al. Icosapent Ethyl\u306b\u3088\u308b\u865a\u8840\u6027\u8133\u5352\u4e2d\u306e\u6e1b\u5c11-REDUCE-IT\u304b\u3089\u306e\u77e5\u898b\u3002Stroke 2021; 52 (Suppl_1).\u56fd\u969b\u8133\u5352\u4e2d\u5b66\u4f1a2021\u53e3\u982d\u767a\u8868\u8981\u65e8 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\u30aa\u30c7\u30c3\u30bb\u30a4\u306e\u6210\u679cPCSK9\u963b\u5bb3\u306f\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u304b\uff1f<\/span><\/h3>\n
21 2021\u5e745\u6708<\/span><\/h6>\n
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\u30ea\u30dd\u86cb\u767d(a) [Lp(a)]\u306e\u4e0a\u6607\u306f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u3001\u708e\u75c7\u6027\u3001\u8840\u6813\u6027\u306a\u3069\u306e\u7279\u6027\u3092\u6709\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u5fc3\u8840\u7ba1\u7cfb\u306e\u5371\u967a\u56e0\u5b50\u3068\u307f\u306a\u3055\u308c\u3066\u3044\u308b\u3002\u89b3\u5bdf\u7814\u7a76\u3067\u306f\uff0cLp(a)\u306e\u4f4e\u5024\u306f\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\uff08\u65b0\u898f\u767a\u75c7\uff09\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u3002Lp(a)\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u85ac\u7406\u5b66\u7684\u85ac\u5264\u304c\u7cd6\u5c3f\u75c5\u767a\u75c7\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u306f\u307e\u3060\u8b70\u8ad6\u306e\u4f59\u5730\u304c\u3042\u308b\u3002\u3053\u306e\u7591\u554f\u306b\u5bfe\u3057\u3066\uff0cODYSSEY OUTCOMES\u306e\u89e3\u6790\u3067\u306f\uff0cLp(a)\u5024\u304c\u6700\u3082\u4f4e\u4e0b\u3057\u305f\u60a3\u8005\u3067\u306f2\u578b\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u308f\u305a\u304b\u306b\u4e0a\u6607\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\uff0c\u3053\u306e\u30ea\u30b9\u30af\u306f\u3053\u306e\u8a66\u9a13\u3067\u89b3\u5bdf\u3055\u308c\u305f\u6b8b\u5b58\u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u6e1b\u5c11\u306b\u3088\u3063\u3066\u306f\u308b\u304b\u306b\u51cc\u99d5\u3055\u308c\u308b\u3068\u601d\u308f\u308c\u308b\u3002 <\/span><\/div>\n
Schwartz GG, Szarek M, Bittner VA et al. \u30ea\u30dd\u86cb\u767d(a)\u30ec\u30d9\u30eb\u30682\u578b\u7cd6\u5c3f\u75c5\u767a\u75c7\u3068\u306e\u95a2\u4fc2\u304a\u3088\u3073\u30a2\u30ea\u30ed\u30af\u30de\u30d6\u6cbb\u7642\u306b\u3088\u308b\u4fee\u98fe\u3002Diabetes Care 2021; https:\/\/care.diabetesjournals.org\/content\/early\/2021\/03\/10\/dc20-2842<\/a> <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTgwMSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

CLEAR OutcomesBempedoic\u9178\uff08ETC-1002\uff09\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u3092\u6295\u4e0e\u3055\u308c\u305f\u30b9\u30bf\u30c1\u30f3\u4e0d\u8010\u6027\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u60a3\u8005\u307e\u305f\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30cf\u30a4\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u8a55\u4fa1<\/span><\/h3>\n
2021\u5e744\u670826\u65e5<\/span><\/h6>\n
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CLEAR Outcomes\u3067\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u4e0d\u8010\u5bb9\u304c\u8a3c\u660e\u3055\u308c\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u5024\u304c\u4e0a\u6607\u3057\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u6b8b\u5b58\u3057\u3066\u3044\u308b\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u304c\u7279\u306b\u767b\u9332\u3055\u308c\u305f\u3002<\/span><\/div>\n
Nicholls SJ\uff0cLincoff AM\uff0cBays HE\u3089\uff1aCLEAR-outcomes\u8a66\u9a13\u306e\u6839\u62e0\u3068\u30c7\u30b6\u30a4\u30f3\uff1a\u30b9\u30bf\u30c1\u30f3\u4e0d\u8010\u5bb9\u60a3\u8005\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u30d9\u30e0\u30da\u30c9\u9178\u306e\u52b9\u679c\u3092\u8a55\u4fa1\u3059\u308b\u3002Am Heart J 2020;235:104-112. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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International Polycap Study-3\uff08TIPS-3\uff09\u3067\u306f\u3001\u4e00\u6b21\u4e88\u9632\u60a3\u8005\u306b\u304a\u3044\u3066\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u4f75\u7528\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<\/span><\/h3>\n
2021\u5e743\u670822\u65e5<\/span><\/h6>\n
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\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607\u3068\u9ad8\u8840\u5727\u3092\u6a19\u7684\u3068\u3057\u305f\u30dd\u30ea\u30d4\u30eb\u3068\u30a2\u30b9\u30d4\u30ea\u30f3\u306e\u4f75\u7528\u7642\u6cd5\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u65e2\u5f80\u306e\u306a\u3044\u4e2d\u7b49\u5ea6\u30ea\u30b9\u30af\u306e\u4eba\u306b\u304a\u3044\u3066\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u309231\uff05\u6e1b\u5c11\u3055\u305b\u305f\u3002<\/span><\/div>\n
Yusuf S, Joseph P, Dans A, et al. \u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u306e\u306a\u3044\u4eba\u306b\u304a\u3051\u308b\u30a2\u30b9\u30d4\u30ea\u30f3\u4f75\u7528\u307e\u305f\u306f\u975e\u4f75\u7528\u306e\u30dd\u30ea\u30d4\u30eb\u3002N Engl J Med 2021; 384:216-228. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTgxMyIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u6291\u5236\u8a66\u9a13\uff08REDUCE-IT\uff09 REVASC<\/span><\/h3>\n
2021\u5e742\u670816\u65e5<\/span><\/h6>\n
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REDUCE-IT\u306e\u6700\u65b0\u30c7\u30fc\u30bf\u306f\u3001\u9ad8\u7528\u91cf\u306e\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u6295\u4e0e\u304c\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08TG\uff09\u5024\u304c\u9ad8\u3044\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306e\u51a0\u52d5\u8108\u8840\u884c\u518d\u5efa\u8853\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/span><\/div>\n
\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u8840\u884c\u518d\u5efa\u8853\u306e\u6e1b\u5c11\uff1aREDUCE-IT REVASC\u304b\u3089\u306e\u77e5\u898b\u3002Circulation 2020; doi 10.1161\/CIRCULATIONAHA.120.050276. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTgxOSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

STRENGTH\uff1a\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u4e2d\u7acb\u7684\u30a2\u30a6\u30c8\u30ab\u30e0\u8a66\u9a13<\/span><\/h3>\n
4 2021\u5e741\u6708<\/span><\/h6>\n
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\u9ad8\u7528\u91cf\u306e\u30aa\u30e1\u30ac-3\u8102\u80aa\u9178\uff08\u30a8\u30a4\u30b3\u30b5\u30da\u30f3\u30bf\u30a8\u30f3\u9178\uff08EPA\uff09\u3068\u30c9\u30b3\u30b5\u30d8\u30ad\u30b5\u30a8\u30f3\u9178\uff08DHA\uff09\u306e\u30ab\u30eb\u30dc\u30f3\u9178\u88fd\u5264\uff09\u306e\u6295\u4e0e\u306f\u3001\u52d5\u8108\u786c\u5316\u6027\u8102\u8cea\u7570\u5e38\u75c7\u3067\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u3092\u6e1b\u5c11\u3055\u305b\u306a\u304b\u3063\u305f\u3002<\/span><\/div>\n
Nicholls SJ, Lincoff AM, Garcia M, et al. \u5fc3\u8840\u7ba1\u7cfb\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u304a\u3051\u308b\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u9ad8\u7528\u91cf\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3068\u30b3\u30fc\u30f3\u6cb9\u306e\u6bd4\u8f03\u52b9\u679c\uff1aSTRENGTH Randomized Clinical Trial\u3002JAMA 2020; doi: 10.1001\/jama.2020.22258. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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2020 <\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u30a8\u30d0\u30dd\u30ec\u30fc\u30c8\uff1a\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb4g\/\u65e5\u3001\u52d5\u8108\u786c\u5316\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b<\/span><\/h3>\n
2020\u5e7410\u67085\u65e5<\/span><\/h6>\n
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EVAPORATE\u8a66\u9a13\uff08Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy\uff09\u306e\u7d50\u679c\u306f\u3001\u753b\u671f\u7684\u306aREDUCE-IT\u8a66\u9a13\u3067\u793a\u3055\u308c\u305f\u9ad8\u7528\u91cf\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u6709\u76ca\u6027\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u6d1e\u5bdf\u3092\u4e0e\u3048\u308b\u3082\u306e\u3067\u3042\u308b\u3002<\/span><\/div>\n
Budoff MJ, Bhatt DL, Kinninger A et al. \u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u4e2d\u306e\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4e0a\u6607\u60a3\u8005\u306b\u304a\u3051\u308b\u51a0\u52d5\u8108\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u306e\u9032\u884c\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u52b9\u679c\uff1aEVAPORATE\u8a66\u9a13\u306e\u6700\u7d42\u7d50\u679c\u3002Eur Heart J 2020; doi:10.1093\/eurheartj\/ehaa652 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTg1NSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u9ad8\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\uff1a\u4e8c\u6b21\u4e88\u9632\u306b\u304a\u3051\u308b\u6e80\u305f\u3055\u308c\u3066\u3044\u306a\u3044\u81e8\u5e8a\u30cb\u30fc\u30ba<\/span><\/h3>\n
2020\u5e747\u670820\u65e5<\/span><\/h6>\n
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Copenhagen General Population Study\u304b\u3089\u5f97\u3089\u308c\u305f\u65b0\u305f\u306a\u77e5\u898b\u306f\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u9ad8\u3044\u975e\u671d\u98df\u6642\u6b8b\u5b58\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u3092\u6a19\u7684\u3068\u3059\u308b\u3053\u3068\u306e\u91cd\u8981\u6027\u3092\u6d6e\u304d\u5f6b\u308a\u306b\u3057\u305f\u3002<\/span><\/div>\n
Langsted A, Madsen CM, Nordestgaard BG.\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u5bfe\u3059\u308b\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5bc4\u4e0e\u3002J Intern Med 2020; doi: 10.1111\/joim.13059.Online ahead of print. <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTg2NiIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u6b8b\u5b58\u30ea\u30dd\u86cb\u767d\u306f\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b<\/span><\/h3>\n
2 2020\u5e746\u6708<\/span><\/h6>\n
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Copenhagen General Population Study\u306e\u30c7\u30fc\u30bf\u306b\u3088\u308b\u3068\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff08TG\uff09\u3068\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u5024\u304c\u9ad8\u304f\u306a\u308b\u3068\u3001\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u3002<\/span><\/div>\n
Kaltoft M, Langsted A, Nordestgaard BG.\u5927\u52d5\u8108\u5f01\u72ed\u7a84\u75c7\u306e\u30ea\u30b9\u30af\u3068\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304a\u3088\u3073\u6b8b\u7559\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff1a\u30b3\u30da\u30f3\u30cf\u30fc\u30b2\u30f3\u4e00\u822c\u4eba\u53e3\u7814\u7a76\u306b\u304a\u3051\u308b\u30e1\u30f3\u30c7\u30eb\u30e9\u30f3\u30c0\u30e0\u5316\u3002Eur Heart J 2020. doi: 10.1093\/eurheartj\/ehaa172 <\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTg3OSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

REDUCE-IT\u306b\u3088\u308b\u3055\u3089\u306a\u308b\u6d1e\u5bdf\uff1a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u7dcf\u6570\u3078\u306e\u5f71\u97ff<\/span><\/h3>\n
2020\u5e743\u670819\u65e5<\/span><\/h6>\n
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\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306f\u3001\u30d0\u30c3\u30af\u30b0\u30e9\u30a6\u30f3\u30c9\u3067\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b2\u578b\u7cd6\u5c3f\u75c5\u304a\u3088\u3073\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u4e0a\u6607\u306e\u3042\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u4e00\u6b21\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u30a4\u30d9\u30f3\u30c8\u304a\u3088\u3073\u5168\u4e00\u6b21\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u30a4\u30d9\u30f3\u30c8\u306e\u8ca0\u62c5\u3092\u8efd\u6e1b\u3057\u305f\u3002<\/span><\/div>\n
Bhatt DL\u3001Steg PG\u3001Miller M\u3089\u3001\u7dcf\u865a\u8840\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u52b9\u679c\u3002REDUCE-IT\u3088\u308a\u3002J Am Coll Cardiol 2019;73:2791’\u00c4\u00ec802. <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTg5MSIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u809dAPOC3\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u7642\u6cd5\u304c\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u60a3\u8005\u306e\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6539\u5584\u3059\u308b<\/span><\/h3>\n
17 2020\u5e742\u6708<\/span><\/h6>\n
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APOC3 mRNA\u306b\u5bfe\u3059\u308b\u3053\u306eN-\u30a2\u30bb\u30c1\u30eb\u30ac\u30e9\u30af\u30c8\u30b5\u30df\u30f3\u7d50\u5408\uff08GalNAc3\uff09\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u30aa\u30ea\u30b4\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306e\u8907\u6570\u56de\u6295\u4e0e\u306f\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306e\u88ab\u9a13\u8005\u306b\u304a\u3044\u3066\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u5024\u3092\u7d0470\uff05\u6e1b\u5c11\u3055\u305b\u305f\u3002<\/span><\/div>\n
Alexander VJ\u3001Xia S\u3001Hurh E\u3089\u3001APOC3mRNA\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u304a\u3088\u3073\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u30ec\u30d9\u30eb\u306b\u5bfe\u3059\u308bN-\u30a2\u30bb\u30c1\u30eb\u30ac\u30e9\u30af\u30c8\u30b5\u30df\u30f3\u7d50\u5408\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u85ac\u3002Eur Heart Journal 2019;40, 2785’\u00c4\u00ec96. <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTg5OCIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2019 <\/span><\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

\u8133\u5352\u4e2d\u3092\u76ee\u6a19\u306b\u6cbb\u7642\u3059\u308b\u7814\u7a76\uff1a\u8133\u5352\u4e2d\u5f8c\u306e\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u76ee\u6a19\u5024\u3092\u4e0b\u3052\u308b\u3068\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u6e1b\u5c11\u3059\u308b<\/span><\/h3>\n
2019 \u5e74 12 \u6708 19 \u65e5<\/span><\/h6>\n
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\u865a\u8840\u6027\u8133\u5352\u4e2d\u307e\u305f\u306f\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\uff08TIA\uff09\u3092\u767a\u75c7\u3057\u3001\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u75c7\u304c\u8a8d\u3081\u3089\u308c\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u4f4e\u6bd4\u91cd\u30ea\u30dd\u86cb\u767d\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\uff08LDL-C\uff09\u5024\u3092< 70 mg\/dL\uff08<1.8mmol\/L\uff09\u307e\u3067\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3001\u3088\u308a\u9ad8\u3044\u76ee\u6a19\u5024\uff0890\uff5e110 mg\/dL [2.3\uff5e2.8mmol\/L]\uff09\u306b\u6bd4\u3079\u3066\u3001\u305d\u306e\u5f8c\u306e\u5fc3\u8840\u7ba1\uff08CV\uff09\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3059\u308b\u3002<\/span><\/div>\n
Amarenco P, Kim JS, Labreuche J et al. \u865a\u8840\u6027\u8133\u5352\u4e2d\u5f8c\u306e2\u3064\u306eLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u76ee\u6a19\u306e\u6bd4\u8f03\u3002N Engl J Med 2019; DOI: 10.1056\/NEJMoa1910355 <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTkxNyIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” background_color=”gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd” custom_margin=”25px||||false|false” custom_padding=”||0px|||” border_radii=”on|20px|20px|20px|20px” global_colors_info=”{%22gcid-b673dc17-1b2a-464e-affa-1bf1ab41c0fd%22:%91%22background_color%22%93}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” header_3_text_color=”gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf” header_6_text_color=”gcid-secondary-color” custom_margin=”||-12px|||” custom_padding=”|28px||28px|false|false” link_option_url_new_window=”on” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22,%22quote_text_color%22%93,%22gcid-4907c8d4-9eff-49de-91ce-43a2d3a729cf%22:%91%22header_3_text_color%22%93,%22gcid-secondary-color%22:%91%22header_6_text_color%22%93}”]<\/p>\n

REDUCE-IT\uff1a\u4e0a\u6607\u3057\u305f\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3092\u6a19\u7684\u3068\u3059\u308b\u3053\u3068\u3067\u3001\u6b8b\u5b58\u3059\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b<\/span><\/h3>\n
2019\u5e747\u670819\u65e5<\/span><\/h6>\n
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REDUCE-IT\uff08Reduction of Cardiovascular Events with EPA-Intervention Trial\uff09\u8a66\u9a13\u3067\u306f\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u304c\u6b8b\u5b58\u3057\u3066\u3044\u308b\u9ad8\u30ea\u30b9\u30af\u306e\u30b9\u30bf\u30c1\u30f3\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a8\u30a4\u30b3\u30b5\u30da\u30f3\u30bf\u30a8\u30f3\u9178\uff08EPA\uff09\u306e\u7cbe\u88fd\u30a8\u30c1\u30eb\u30a8\u30b9\u30c6\u30eb\u3067\u3042\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u3092\u6295\u4e0e\u3059\u308b\u3068\u3001\u4e3b\u8981\u306a\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c25\uff05\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u307e\u305f\u3001\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u6cbb\u7642\u306f\u865a\u8840\u6027\u30a4\u30d9\u30f3\u30c8\u306e\u7dcf\u8ca0\u62c5\u3092\u5927\u5e45\u306b\u6e1b\u5c11\u3055\u305b\u305f\u3002 <\/span><\/div>\n
Bhatt DL\u3001Steg PG\u3001Miller M\u3089\u3001\u9ad8\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u8840\u75c7\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u3002N Engl J Med 2019;380:11-22.Bhatt DL\u3001Steg PG\u3001Miller M\u3089\u3001\u7dcf\u865a\u8840\u30a4\u30d9\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u30a4\u30b3\u30b5\u30da\u30f3\u30c8\u30a8\u30c1\u30eb\u306e\u52b9\u679c\uff1aREDUCE-IT\u3088\u308a\u3002J Am Coll Cardiol 2019;73:2791-802. <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_button button_url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTkzMiIsImVuYWJsZV9odG1sIjoib2ZmIn19@” url_new_window=”on” button_text=”\u7d9a\u304d\u3092\u8aad\u3080” button_alignment=”right” _builder_version=”4.27.4″ _dynamic_attributes=”button_url” _module_preset=”9bc3f405-43a0-4056-a483-11952257355c” button_bg_color=”RGBA(255,255,255,0)” button_icon=”$||divi||400″ button_icon_color=”gcid-primary-color” button_on_hover=”off” custom_margin=”|44px|||false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22button_text_color%22,%22button_icon_color%22%93}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”15px” header_2_text_color=”gcid-primary-color” header_2_font_size=”32px” custom_margin=”||-13px|||” custom_padding=”9px|||27px|false|false” global_colors_info=”{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22%93}”]<\/p>\n

2018 <\/span><\/h2>\n

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CANTOS\u304b\u3089\u306e\u30cb\u30e5\u30fc\u30b9\uff1a\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u306e\u8abf\u7bc0\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b<\/span><\/h3>\n
2018 \u5e74 11 \u6708 6 \u65e5<\/span><\/h6>\n
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Canakinumab Anti-Inflammatory Thrombosis Outcomes Study\uff08CANTOS\uff09\u304b\u3089\u5f97\u3089\u308c\u305f\u65b0\u305f\u306a\u77e5\u898b\u306b\u3088\u308a\u3001\u30ab\u30ca\u30ad\u30cc\u30de\u30d6\u306b\u3088\u308b\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-6\uff08IL-6\uff09\u7d4c\u8def\u306e\u6a19\u7684\u5316\u304c\u3001\u8102\u8cea\u4f4e\u4e0b\u3068\u306f\u7121\u95a2\u4fc2\u306b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3068\u3044\u3046\u6982\u5ff5\u5b9f\u8a3c\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u5f97\u3089\u308c\u305f\u3002<\/span><\/div>\n
Ridker PM\u3001Libby P\u3001MacFadyen JG\u3089\uff1a\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-6\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u306e\u8abf\u7bc0\u3068\u30a2\u30c6\u30ed\u30fc\u30e0\u6027\u52d5\u8108\u786c\u5316\u6027\u30a4\u30d9\u30f3\u30c8\u304a\u3088\u3073\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306e\u767a\u751f\u7387\uff1a\u30ab\u30ca\u30ad\u30cc\u30de\u30d6\u6297\u708e\u75c7\u6027\u8840\u6813\u75c7\u30a2\u30a6\u30c8\u30ab\u30e0\u7814\u7a76\uff08CANTOS\uff09\u306e\u89e3\u6790\u3002Eur Heart J 2018; doi:10.1093\/eurheartj\/ehy310 <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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