{"id":255325,"date":"2025-04-06T20:46:23","date_gmt":"2025-04-06T18:46:23","guid":{"rendered":"https:\/\/r3i.org\/?page_id=255325"},"modified":"2025-04-14T18:49:07","modified_gmt":"2025-04-14T16:49:07","slug":"folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash","status":"publish","type":"page","link":"https:\/\/r3i.org\/es\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\/","title":{"rendered":"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)"},"content":{"rendered":"

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Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)<\/h3>\n

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Prof Michel P.Hermans, Prof. Jean-Charles Fruchart, y Dra. Jamila Fruchart-Najib<\/h6>\n

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La enfermedad de hi\u0301gado graso asociada a la disfuncio\u0301n metabo\u0301lica (MAFLD)<\/span>1<\/span>, antes conocida como enfermedad de hi\u0301gado graso no alcoho\u0301lico (NAFLD), es un te\u0301rmino gene\u0301rico que cubre el espectro de las enfermedades por hi\u0301gado graso, que va desde la esteatosis aislada hasta la forma ma\u0301s grave, la esteatohepatitis asociada a la disfuncio\u0301n metabo\u0301lica (MASH)<\/span>1<\/span>, antes conocida como esteatohepatitis no alcoho\u0301lica (NASH). Durante las u\u0301ltimas tres de\u0301cadas, la prevalencia de MAFLD ha aumentado en ma\u0301s del 50%, en paralelo con el aumento de las pandemias de obesidad, prediabetes y diabetes tipo 2, lo que afecta a ma\u0301s del 30% de la poblacio\u0301n general global<\/span>2<\/span>. El aumento de la prevalencia de MASH ha ocasionado que se convierta en la causa principal de trasplante de hi\u0301gado en Estados Unidos y Europa<\/span>3<\/span>. <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)Prof Michel P.Hermans, Prof. Jean-Charles Fruchart, y Dra. Jamila Fruchart-Najib La enfermedad de hi\u0301gado graso asociada a la disfuncio\u0301n metabo\u0301lica (MAFLD)1, antes conocida como enfermedad de hi\u0301gado graso no alcoho\u0301lico (NAFLD), es un te\u0301rmino gene\u0301rico que cubre el espectro de las enfermedades por hi\u0301gado graso, que va desde la […]<\/p>\n","protected":false},"author":258497324,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" admin_label=\"Header\" _builder_version=\"4.27.4\" _module_preset=\"8a9a809c-7a33-46fa-a9c3-6cbb2909b12a\" background_image=\"https:\/\/r3i.org\/wp-content\/uploads\/2024\/12\/Design-sans-titre.png\" parallax=\"on\" custom_padding=\"1vw||1vw||true|false\" collapsed=\"on\" global_colors_info=\"{%22gcid-primary-color%22:%91%22quote_text_color%22,%22background_color_gradient_stops%22%93}\"][et_pb_row column_structure=\"2_3,1_3\" _builder_version=\"4.27.0\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_column type=\"2_3\" _builder_version=\"4.27.0\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_heading title=\"Folletos\" _builder_version=\"4.27.3\" _module_preset=\"a97d2c6e-7b99-4859-b03c-bd1a8625b1d7\" title_font=\"Poppins||||||||\" title_text_align=\"left\" title_text_color=\"#FFFFFF\" title_font_size=\"65px\" custom_margin=\"||10px||false|false\" text_shadow_style=\"preset1\" global_colors_info=\"{}\"][\/et_pb_heading][\/et_pb_column][et_pb_column type=\"1_3\" _builder_version=\"4.27.0\" _module_preset=\"default\" global_colors_info=\"{}\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.27.4\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_row column_structure=\"1_2,1_2\" _builder_version=\"4.27.4\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_column type=\"1_2\" _builder_version=\"4.27.4\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_image src=\"https:\/\/r3i.org\/wp-content\/uploads\/2024\/12\/Screenshot-2024-12-17-at-22.45.55.png\" title_text=\"Captura de pantalla 2024-12-17 a las 22.45.55\" _builder_version=\"4.27.4\" _module_preset=\"default\" global_colors_info=\"{}\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.27.4\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" header_2_text_color=\"gcid-primary-color\" header_3_text_color=\"gcid-primary-color\" custom_margin=\"||3px|||\" global_colors_info=\"{%22gcid-primary-color%22:%91%22quote_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22%93}\"]

Diferenciar SPPARM\u03b1 y fibratos (agonistas PPAR\u03b1)<\/a><\/h3>[\/et_pb_text][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" header_6_text_color=\"#000000\" global_colors_info=\"{}\"]
Por el profesor Jean-Charles Fruchart <\/h6>[\/et_pb_text][et_pb_button button_url=\"https:\/\/r3i.org\/wp-content\/uploads\/2025\/02\/Differentiating-SPPARM-Booklet-spanish.pdf\" url_new_window=\"on\" button_text=\"Descargar folleto\" button_alignment=\"center\" _builder_version=\"4.27.4\" _module_preset=\"default\" hover_enabled=\"0\" global_colors_info=\"{}\" sticky_enabled=\"0\"][\/et_pb_button][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_font_size=\"14px\" global_colors_info=\"{}\"]

La enfermedad cardiovascular ateroscler\u00f3tica (ECVA) es un reto sanitario mundial cada vez mayor, exacerbado por un panorama cambiante de factores de riesgo asociados a enfermedades cr\u00f3nicas relacionadas con el estilo de vida, como la obesidad visceral, la diabetes mellitus tipo 2 (DMT2) y la enfermedad del h\u00edgado graso no alcoh\u00f3lico. La dislipidemia aterog\u00e9nica, triglic\u00e9ridos elevados con o sin niveles bajos de colesterol de lipoprote\u00ednas de alta densidad, es frecuente en individuos de alto riesgo, especialmente en los que padecen DMT2, y contribuye al riesgo cardiovascular residual a pesar de un control \u00f3ptimo del colesterol de lipoprote\u00ednas de baja densidad.<\/span><\/p>\n

Opciones actuales para tratar los problemas de dislipidemia aterog\u00e9nica, especialmente para la seguridad renal y hep\u00e1tica. Es evidente que se necesitan nuevos enfoques.<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]","_et_gb_content_width":"","_crdt_document":"","footnotes":""},"class_list":["post-255325","page","type-page","status-publish","hentry"],"yoast_head":"\nFolleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH) - R3I<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/r3i.org\/es\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH) - R3I\" \/>\n<meta property=\"og:description\" content=\"Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)Prof Michel P.Hermans, Prof. Jean-Charles Fruchart, y Dra. Jamila Fruchart-Najib La enfermedad de hi\u0301gado graso asociada a la disfuncio\u0301n metabo\u0301lica (MAFLD)1, antes conocida como enfermedad de hi\u0301gado graso no alcoho\u0301lico (NAFLD), es un te\u0301rmino gene\u0301rico que cubre el espectro de las enfermedades por hi\u0301gado graso, que va desde la […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/r3i.org\/es\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\/\" \/>\n<meta property=\"og:site_name\" content=\"R3I\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-14T16:49:07+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\\\/\",\"url\":\"https:\\\/\\\/r3i.org\\\/es\\\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\\\/\",\"name\":\"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH) - R3I\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#website\"},\"datePublished\":\"2025-04-06T18:46:23+00:00\",\"dateModified\":\"2025-04-14T16:49:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/r3i.org\\\/es\\\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/r3i.org\\\/es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#website\",\"url\":\"https:\\\/\\\/r3i.org\\\/es\\\/\",\"name\":\"R3I\",\"description\":\"Residual Risk Reduction Initiative\",\"publisher\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/r3i.org\\\/es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#organization\",\"name\":\"R3I\",\"url\":\"https:\\\/\\\/r3i.org\\\/es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/i0.wp.com\\\/r3i.org\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/r3i-logo-transp-1.png?fit=1601%2C834&ssl=1\",\"contentUrl\":\"https:\\\/\\\/i0.wp.com\\\/r3i.org\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/r3i-logo-transp-1.png?fit=1601%2C834&ssl=1\",\"width\":1601,\"height\":834,\"caption\":\"R3I\"},\"image\":{\"@id\":\"https:\\\/\\\/r3i.org\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH) - R3I","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/r3i.org\/es\/folleto-esteatohepatitis-asociada-con-la-disfuncion-metabolica-mash\/","og_locale":"es_ES","og_type":"article","og_title":"Folleto : Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH) - R3I","og_description":"Esteatohepatitis asociada con la disfunci\u00f3n metab\u00f3lica (MASH)Prof Michel P.Hermans, Prof. Jean-Charles Fruchart, y Dra. 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